38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
AJAS · 2020
Biomedical and Health Sciences (inferred)
Retinopathy of Prematurity (ROP), observed in premature infants with low birth weight, is a leading cause of blindness worldwide. ROP shows no external signs or symptoms. Normal blood vessel…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Grade IV glioblastoma is the most lethal and aggressive brain tumor in adults. Despite treatment advances combining maximal surgical resection with radiotherapy and concurrent adjuvant chemo…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Diabetes is a disease that can require the hormone insulin to be prescribed as a treatment, resulting in inconvenience and possible deleterious conditions for patients due to the drug’s inje…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Lifelong ingestion of glucose has been proven to significantly shorten lifespan in C. elegans, a worm with an evolutionarily conserved insulin signaling pathway, similar to that of humans. T…
AJAS · 2020
Biomedical and Health Sciences (inferred)
The use of antidepressants during pregnancy is estimated at 15% of the pregnant population in the United States. The most widely-prescribed antidepressants for pregnant women are called sele…
AJAS · 2020
Biomedical and Health Sciences (inferred)
E-cigarettes/vapes have become popular in the past decade due partly to marketing as alternatives to traditional cigarettes. Flavor varieties and availability have made them popular and they…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Serotonin is a neurotransmitter that is thought to affect mood in humans. A common class of prescription drugs used to treat symptoms of depression are selective serotonin reuptake inhibitor…
AJAS · 2020
Biomedical and Health Sciences (inferred)
It is evident that Cancer-Associated Fibroblasts (CAFs) are key regulators of the immune system to assist the tumor in immune evasion, however, little research has been conducted on the mech…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Currently, over 415 million people worldwide have diabetes and within that population, 90% - 95% have type 2 diabetes; increasingly more children and young adults are also developing it. The…
AJAS · 2019
Biomedical and Health Sciences (inferred)
Neurodegenerative disorders affect millions of people across the globe, with approximately 50 million people worldwide diagnosed with Alzheimer’s disease (AD). However, this figure is likely…
AJAS · 2019
Biomedical and Health Sciences (inferred)
Abstract Multiple sclerosis (MS) is a chronic, demyelinating autoimmune disease of the central nervous system (CNS) initiated and perpetuated by T cells responding to a number of myelin anti…
AJAS · 2019
Biomedical and Health Sciences (inferred)
Fetal Alcohol Syndrome (FAS) can occur when a pregnant woman consumes alcohol. Prenatal alcohol consumption may cause abnormalities in the fetus including craniofacial, neurobehavioral and c…
AJAS · 2019
Biomedical and Health Sciences (inferred)
Glucose has been shown to shorten the lifespan of the nematode C. elegans that has an evolutionarily conserved insulin signaling pathway similar to that of humans. This study examined the ef…
AJAS · 2019
Biomedical and Health Sciences (inferred)
Type 2 diabetes affects over 300 million people worldwide. Initially, insulin resistance leads to decreased glucose uptake by peripheral metabolic organs. This decrease in uptake of glucose…
AJAS · 2019
Biomedical and Health Sciences (inferred)
Cytomegalovirus (CMV) is the leading non-genetic cause of sensorineural hearing loss (SNHL) in children in the United States. Current antiviral treatments exist, however with only modest sho…
AJAS · 2019
Biomedical and Health Sciences (inferred)
One in eleven people will have a form of diabetes during their lifetime (WHO, 2014). In 2012, diabetes and its life-threatening side effects costed 245 billion dollars in the United States (…
AJAS · 2019
Biomedical and Health Sciences (inferred)
Ovarian cancer is the fifth leading cause of cancer death among American women, in large part due to failure to diagnose the disease before it has spread to other organs. Recently, a change…
AJAS · 2019
Biomedical and Health Sciences (inferred)
atRAL, a cytotoxic byproduct of the visual cycle, is removed from the eyes’ photoreceptors by ATP-binding cassette transporter (ABCA4), which transports atRAL from the disc lumen to the cyto…
AJAS · 2019
Biomedical and Health Sciences (inferred)
Macrophages infiltrate the dorsal root ganglia (DRG) and the sciatic nerve (SN) distal to the site of injury after peripheral nerve axotomy. Injury induced expression of the chemokine CCL2 i…
AJAS · 2019
Biomedical and Health Sciences (inferred)
The objective of this study was to understand the effects of acetaminophen on Caenorhabditis elegans lifespan and fertility. The experiment was based off a study that assessed the effect of…
AJAS · 2019
Biomedical and Health Sciences (inferred)
Serotonin is a neurotransmitter that is thought to be responsible for mood in humans and other multicellular organisms. Many people take prescription drugs that are thought to increase level…
AJAS · 2018
Biomedical and Health Sciences (inferred)
On average, 15,780 cases of pediatric cancer are diagnosed within the United States annually. Furthermore, pediatric solid tumors account for about 30 percent of all cases of pediatric cance…
AJAS · 2018
Biomedical and Health Sciences (inferred)
The prevalence of obesity has led to increased incidence of diseases including heart disease, high blood pressure and diabetes. Biologically, lipids from obesity-inducing foods are stored in…
AJAS · 2018
Biomedical and Health Sciences (inferred)
Background: Duchenne muscular dystrophy (DMD) is an X-linked recessive neuromuscular disease resulting from mutations in the dystrophin gene and it affects 1 in 5,000 males. In 2017, DMD-ass…
AJAS · 2018
Biomedical and Health Sciences (inferred)
Antigenic similarity between tumor cells and embryonic stem cells has been recognized for many years. However, treatments harnessing this similarity have achieved little success, largely due…
AJAS · 2018
Biomedical and Health Sciences (inferred)
Rheumatoid Arthritis (RA), the most common form of autoimmune arthritis, is a progressive inflammatory autoimmune disease with unclear causes. The objective of this project was to assess how…
AJAS · 2018
Biomedical and Health Sciences (inferred)
Introduction: Inflammation and infection are important in the etiopathogenesis of pulmonary diseases. Umbilical cords are usually discarded postdelivery. Mesenchymal stem cells (hMSCs) deriv…
AJAS · 2018
Biomedical and Health Sciences (inferred)
The ability of microRNAs to regulate oncogenes through RNA interference makes them a promising target in cancer therapy. Specifically, miR-200c has gained attention in triple negative breast…
AJAS · 2018
Biomedical and Health Sciences (inferred)
Hyperthyroidism, a dangerous disease caused by the over activity of the Thyroid gland, severely weakens the body’s metabolism and leads to stroke, heart failure, and other life-threatening d…
AJAS · 2018
Biomedical and Health Sciences (inferred)
Many smokers believe the concept that e-cigarettes are a healthy alternative for the otherwise prejudicial cigarettes. Although they are not as harsh as traditional cigarettes, these perilou…