Browse real student projects, abstracts, and awards.
ISEF · 2026
Translational Medical Science
Breast cancer is the leading cause of cancer-related death among women, with approximately 42,000 deaths annually in the United States and over 700,000 worldwide. Brain metastases represent…
CWSF · 2026
Disease & Illness
Glioblastoma is one of the most aggressive forms of brain cancer with a 5-year survival rate of less than 10%. My project focused on using Adeno-Associated Virus (AAV) as a vessel for gene t…
ISEF · 2026
Translational Medical Science
Neurodegenerative diseases like Alzheimer's affect millions worldwide, yet current diagnostic methods remain invasive, expensive, and largely inaccessible during the critical early intervent…
CWSF · 2026
Disease & Illness
Imagine if we could control how cells behave when there is a disease in our body. Scientists are doing this by targeting the tiny survival manual inside our cells called DNA with a tool call…
CWSF · 2026
Disease & Illness
Dementia and Alzheimer's disease are leading problems for seniors today, affecting millions of individuals worldwide. Symptoms of these conditions include cognitive impairment, personality c…
CWSF · 2026
Health & Wellness Bronze Medal
When writing braille by hand, the writer will often use a braille slate. Using a standard braille slate, they write from the back of the page, which creates a unique challenge as the letters…
CWSF · 2026
Health & Wellness
Swallowing pills can be a massive fear and nuisance, that begs the question; does the size of pharmaceutical capsules affect how fast they dissolve in our bodies? There were three capsule si…
ISEF · 2026
Translational Medical Science
Helicobacter pylori infects over 4.4 billion people and is a WHO Group 1 carcinogen linked to gastric cancer. Rising antibiotic resistance, particularly to clarithromycin (>30% in many regio…
ISEF · 2026
Translational Medical Science
Drug repurposing involves identifying new therapeutic uses for existing drugs that have already been approved or tested for other diseases, offering a faster and lower-cost alternative to tr…
CWSF · 2026
Disease & Illness Silver Medal
Every 40 seconds someone has a stroke and up to 30% are caused by a heart condition called atrial fibrillation that produces zero warning signs until it's too late. We built a portable heart…
CWSF · 2026
Disease & Illness Bronze Medal
Our project focuses on using statistical measures to make comparisons between the different factors that can affect Alzheimer’s disease cognitive trajectories. Firstly, we conducted a meta-a…
CWSF · 2026
Health & Wellness
Invisible to the naked eye but potentially harmful to our health, airborne bacteria are a hidden threat that demand an effective mitigation strategy. This study investigated the effect of sa…
CWSF · 2026
Disease & Illness Silver Medal
Alzheimer's disease is a neurodegenerative disorder affecting millions, characterized by accumulation of amyloid beta oligomers causing neuronal dysfunction. The ubiquitin-proteasome system…
ISEF · 2026
Biomedical and Health Sciences
Protamine 1 (PRM1) and protamine 2 (PRM2) are essential for packaging sperm DNA and maintaining genome stability during spermatogenesis. Changes in their expression levels are associated wit…
ISEF · 2026
Translational Medical Science
Neurodegenerative diseases, including Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI), are typically diagnosed after 50-80% neuronal loss, reflecting a critical failure of early…
ISEF · 2026
Translational Medical Science
Visual impairment (VI) affects 2.2 billion people worldwide, and 1 billion cases are preventable with early diagnosis. Retinal diseases are preventable causes of VI. Clinical Decision Suppor…
ISEF · 2026
Biomedical and Health Sciences
Despite advances in immunotherapy, up to 60% of melanoma patients do not respond to treatment. Emerging evidence suggests that physical exercise enhances anti-tumor immunity; however, the mo…
CWSF · 2026
Disease & Illness Gold Medal
Nearly 50% of IVF embryos arrest before they become viable pregnancies, and the molecular mechanisms causing this failure remain poorly understood. The Digital Embryo is the first multi-omic…
ISEF · 2026
Translational Medical Science
Purpose: About 7.2 million Americans are living with Alzheimer's Disease (AD), with the number expected to to double by 2060. Currently used drugs for AD only reduce disease symptoms and mar…
CWSF · 2026
Disease & Illness Bronze Medal
Pediatric Pneumonia is the leading infectious cause of death for children worldwide [1], largely due to slow or incorrect diagnosis [2]. Even with advancements in machine learning, modern AI…
ISEF · 2026
Biomedical and Health Sciences
This project is a three year study in investigating possible advancements that could made in the medical world. I created 3D printed casts and did comparative testing with different, more mo…
CWSF · 2026
Health & Wellness
In an age of rising conflict, there has been a significant increase in limb loss especially for the pediatric population. Yet the sustainability and cost associated with traditional prosthet…
CWSF · 2026
Disease & Illness Gold Medal
Anorexia Nervosa is a severe psychiatric disorder that primarily impacts teenage girls. This condition is especially challenging due to the lack of concrete biomarkers, such as structural ch…
ISEF · 2026
Translational Medical Science
Pancreatic cancer is one of the deadliest cancers in the world, largely due to late-stage diagnosis. Current imaging diagnostic tools like CT and MRI scans lack the accuracy and sensitivity…
ISEF · 2026
Biomedical and Health Sciences
Dehydration is one of the leading causes of hospital admissions. Evaluations to measure hydration status in clinical settings utilize methods such as blood tests, urinalysis, and skin turgor…
ISEF · 2026
Translational Medical Science
Airborne Neurotropic Viruses (ANVs) are emergent invasive neuropathogens, affecting 300-500 million people and being responsible for >700,000 deaths annually. Early neurotropic transcriptomi…
ISEF · 2026
Biomedical and Health Sciences
Diabetes mellitus is a metabolic disorder resulting in the dysregulation of blood glucose (BG), affecting more than 14% of adults. BG is typically regulated by the pancreatic hormone insulin…
ISEF · 2026
Translational Medical Science
Parkinson’s Disease (PD) is a chronic and progressive neurodegenerative disease associated with the deterioration of motor control and cognitive function as age advances. Representing the fa…
CWSF · 2026
Disease & Illness Platinum Award
Sepsis claims 11 million lives annually, but current diagnostics are costly and often ineffective. Aptamers are single-stranded DNA or RNA sequences that are promising for detecting proteomi…
CWSF · 2026
Health & Wellness
Extreme temperatures pose significant threats to human health. Each year, millions of deaths are linked to cold-related conditions, while extreme heat causes around 489,000 deaths. Early sym…