AJAS projects, 2017–2026

ALLocate: Auto Ai Live Localization and Classification of Myeloid Leukemia in Bone Marrow

The accurate leukemia detection in current clinical practice still remains challenging due to limitations in cost, time, and medical experience. To address this issue, this study aims to dev…

Aloe Vera: Enhancing Collagen Formation for Dermal Wound Healing in Porcine Skin

Biomedical Engineering (inferred)

This study determines the efficacy of Aloe vera sap in promoting collagen synthesis during the wound healing process, using burn-injured porcine skin as a model. Viable porcine skin samples…

ALS-SynAegis: A Molecular Dynamics Study on TDP-43 Aggregation to Prevent ALS Onset

Amyotrophic Lateral Sclerosis is a devastating neurodegenerative disease characterized by progressive muscle atrophy, leading to an inability to move the limbs and, in extreme cases, being u…

Analysis of Bathymetric Relationships Between Wave Metrics and Sand Movement

Earth and Environmental Sciences (inferred)

As sea levels rise and increase the rates of shoreline recession around coastal communities, developing strategies to mitigate this erosion should involve an examination of near-shore bathym…

Analyzing HLA Sequences to Predict Organ Rejection and Find Targets for Immunosuppression

Computational Biology and Bioinformatics (inferred)

Organ rejection is a dangerous medical complication that can occur after an organ transplant. Currently, all transplant patients are prescribed life-long immunosuppressors to decrease the ri…

A Novel Hadronization Model for Charm-Quark

Physics and Astronomy (inferred)

The study of hadronization, the process of quarks combined into hadrons, is pivotal for understanding the universe's formation, yet current theories inadequately explain this process. This s…

Auto-Detection and Classification of Arrhythmias with ECG Signal Analysis

Biomedical and Health Sciences (inferred)

Cardiac arrhythmias represent a significant global health challenge, affecting millions annually and frequently leading to misdiagnosis and inappropriate treatment. Consequently, 75% of arrh…

Automated Detection of Multiple Sclerosis Using Machine Learning

Multiple Sclerosis (MS) is a complex neurological disorder characterized by nerve damage to the central nervous system, affecting over two million people worldwide. Symptoms include but are…

Automated Early Detection of Diabetic Retinopathy Using Deep Learning

Biomedical and Health Sciences (inferred)

Diabetic retinopathy (DR) is a microvascular eye condition that can lead to vision loss and blindness in individuals with diabetes. DR has been on the rise over the past 30 years and is the…

Bile Acid-Derived Antibiotic via Dye Leakage Use Bacterial Membrane-Mimicking Lipid Vesicles

Microbiology (inferred)

Antibiotics have revolutionized medicine, saving millions of lives since the initial discovery of penicillin in the 1930s. Since then, numerous antibiotics have been developed to treat a var…

Biodiversity of Mushrooms in Northern New Jersey

Researching the biodiversity of fungi is imperative for ecological conservation. The environmental impacts mushrooms hold reach far beyond their common role as decomposers as they can indica…

Biomechanical Position Differences Between Running Barefoot Versus Running with Shoes

Biomedical Engineering (inferred)

Humans are most biomechanically efficient without shoes. Does this mean that the use of shoes puts our body in a worse biomechanical position to run? This project seeks to find an answer to…

Breast Cancer in Young Women: Microbiota, Estrogen, and Bacteria Impact on Biomarker Discovery

Breast cancer rates have surged among adolescent and young women in the U.S., remaining a main cause of cancer deaths in this demographic. This issue calls for quicker and more efficient dia…

Can They Eat It?: Creating an Eco- and Livestock-Friendly Hay String

When cattle or other livestock eat hay wrap or hay string it causes the animal to die because the string is a filler and is not digestible so the animal thinks they are not hungry because th…

CDK9-Specific PROTAC 2 Treatment Sensitizes Pancreatic Cancer Cells to Navitoclax

Biomedical and Health Sciences (inferred)

Pancreatic Cancer (PC) has the highest mortality rate of all major cancers. PC is currently the third leading cause of cancer-related death, with a 5-year survival rate of 13% in the United…

Characterizing Baz1a: Designing Cell Labeling Strategy and Development of Hi-Res Neuron Model

The human brain and the neurons that compose it remain some of the greatest mysteries facing scientists today. Though the basic structure of a neuron is known, an updated and detailed model…

Cheap Fluorescence Microscope Using Photoacoustic Effect to Alter Sample Fluorescence

Fluorescence microscopes are a pivotal component of scientific research. However, they are expensive and can cause photobleaching in specimens over long exposure periods. These issues are re…

Chebulinic and Gallic Acid Treat Novel Targets in Alzheimer's Disease

Alzheimer's Disease (AD), a neurodegenerative disorder affecting millions yearly, remains a leading cause of death with no cure. Previous studies have conflicted over the impact of amyloid b…

Clinical Testing on the Internet of Things Automatic Chair for Fall Risks

Muscle weakness is the most significant indicator of age-related loss of function and is associated with poor mobility and mortality. Limitations in the person's ability to stand reflect mus…

Comparing Vitamin C and E in Improving Photostability of Heat-Degraded Retinol

Retinol, a form of Vitamin A, is a popular ingredient in skincare products for its anti-aging effects. However, in most cosmetic formulations, retinol destabilizes quickly, due to exposure t…

CoMPHI: A Composite Machine Learning Approach to Predict Hosts of Bacteriophages

Phage therapy has reemerged as a compelling alternative to antibiotics in treating bacterial infections, especially antibiotic-resistant superbugs. The challenge in the broader application o…

Computational Chemistry Study: Analyzing the Most Stable Conformations of Linalool

Chemistry (inferred)

Linalool is a fragrant monoterpene alcohol present in essential oils like lavender and basil. It exhibits significant biological properties, including antibacterial and sterilization charact…

Creating a Drought Prediction Model Using Convolutional Neural Networks

Earth and Environmental Sciences (inferred)

Droughts kill over 45,000 people yearly and affect the livelihoods of 55 million others, with climate change likely to worsen these effects. Despite this, researchers have struggled to dev…

DAtect: Forecasting Domoic Acid Levels from Algal Blooms in the Pacific Northwest Coast

Earth and Environmental Sciences (inferred)

In spring 2015, the U.S. Pacific Coast experienced an unprecedented spike in domoic acid concentrations, surpassing federal safety limits by over 700% in parts of Washington State and trigge…

Decoding ASXL3: a Novel Biomarker and Treatment for Neurodevelopmental Disorders

Cellular and Molecular Biology (inferred)

In a recent study, 33% of individuals with neurodevelopmental disorders (NDDs) carried mutations in ASXL3, whose function is unknown. To understand ASXL3’s role in NDDs, we used CRISPR tec…

Decoding ASXL3: Novel Biomarker and Treatment

In a recent study, 33% of individuals with neurodevelopmental disorders (NDDs) carried mutations in ASXL3, whose function is unknown. To understand ASXL3’s role in NDDs, we used CRISPR tec…

Derivations for Coupled GPS-Iceberg-Sea Level Anomaly Model Projecting Sea Level Rise

Earth and Environmental Sciences (inferred)

As a major source of sea-level rise, iceberg melting increases freshwater input and can also cause regional water imbalances, scarcity, and natural disasters. In this paper, we use a more ac…

Design of an Active Magnetic Field Stabilization System for Quantum Gas Experiments

Physics and Astronomy (inferred)

Bose-Einstein Condensates (BECs) are a novel state of matter that exhibit unique characteristics where groups of atoms behave as a macroscopic wavefunction. BECs can be highly sensitive to m…

Design Synthesis and Testing in Silico of New Antibody Drug Conjugate of Neratinib

Antibody-drug conjugates (ADCs) offer significant advantages over traditional cancer therapies by enabling the targeted delivery of potent cytotoxic small-molecule drugs (payloads), such as…

Detecting Suicide Risk and Contributing Factors Using Social Media Data

Behavioural and Social Sciences (inferred)

Suicide remains a critical global health issue, with over 700,000 lives lost annually. Existing research has explored factors influencing suicidal thoughts, but traditional studies often rel…