38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
The blood–brain barrier (BBB) is a selective physiological barrier that regulates the movement of molecules between the bloodstream and the central nervous system. In neuroinflammatory condi…
CSEF · 2026
Biochemistry/ Molecular Biology (Junior Division)
Malignant peripheral nerve sheath tumors (MPNSTs) are a rare and aggressive cancer that develops from nerve tissues, affecting about 1 in 100,000 people. These tumors are difficult to remove…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
The precise and effective evaluation of surgical recovery presents significant challenges in the medical field, and current methods for evaluating recovery can be invasive, subjective, and e…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
Hemorrhage remains a leading cause of preventable death in trauma, battlefield injury, obstetric emergencies, and mass casualty events because definitive care is often delayed by limited acc…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
Eczema, or atopic dermatitis, affects 30% of children and 10% of adults in the United States (NIH). While corticosteroids suppress inflammation, they weaken the skin barrier, causing recurre…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
Cancer combination therapy may enhance therapeutic efficacy by concurrently targeting multiple survival pathways; however, experimentally evaluating millions of potential drug pairs is neith…
CSEF · 2026
Biochemistry/ Molecular Biology (Junior Division)
Since ultraviolet (UV) radiation from sunlight damages the DNA of living cells, protecting cells is important to lead a healthy life. One way cells could be protected is through the use of n…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
Early cancer detection is commonly framed as a classification problem, yet such approaches rarely address whether early disease states are physically detectable in molecular data at all. Her…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
Rapid identification of respiratory pathogens is essential for selecting the appropriate treatment, especially in primary care clinics and developing areas with limited medical resources. I…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
The molecular mechanisms driving the transition from Idiopathic Pulmonary Fibrosis (IPF) to Lung Adenocarcinoma (LUAD) remain unresolved. Since 70% of IPF-associated tumors arise within exis…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
Drug resistance remains a critical challenge in oncology, necessitating the identification of quantitative biomarkers for therapeutic evasion. This study investigated the extent to which Sha…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
Background: Sertoli cells (SCs) play an important role in the development and function of the testes and in the process of spermatogenesis (generation of sperm). They are nurse cells, which…
CSEF · 2026
Biochemistry/ Molecular Biology (Junior Division)
Introduction Glioblastoma is a highly malignant brain tumor characterized by aggressive growth, frequent recurrence, and limited treatment options. Glioblastoma cells produce the S100A16 pro…
CSEF · 2026
Biochemistry/ Molecular Biology (Junior Division)
Globally, each year 20 million people are diagnosed with cancer. 61% of these people struggle with paying for expensive treatments like Neo-antigen therapies which cost $100,000, and CAR-T-c…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
Caffeine is commonly consumed in drinks such as coffee and energy drinks, often together with foods that contain fats. Because caffeine is sometimes linked to weight loss and metabolism, I w…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
About 125 million people in the U.S. are affected by inflammatory disorders; despite this, there are no viable cures for these conditions. Many researchers have turned away from natural prod…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
This project investigates the effects of three synthetic chalcones, compounds 17, 25, and 30, on Caenorhabditis elegans. This nematode species was used as a non-parasitic model for plant-par…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
Focal Cortical Dysplasia (FCD) causes epilepsy in 4 million newborns yearly. Treatments are surgical removal of malformed brain tissue, which fails for 40% of patients and causes permanent c…
CSEF · 2026
Biochemistry/ Molecular Biology (Junior Division)
Microbial Fuel Cells (MFCs) are a promising technology that generate electricity through the metabolic processes of bacteria such as Geobacter and Shewanella. These bacteria release electron…
CSEF · 2026
Biochemistry/ Molecular Biology (Junior Division)
The purpose of my project is to find which fruit has the most sugar by measuring it with a refractometer (Sugar Brix). All ripe fruits that I used for my experiment are pineapple,grapes, gol…
CSEF · 2026
Biochemistry/ Molecular Biology (Junior Division)
The purpose of this project was to determine whether the nutritional value of eggs varies based on their source. Samples were collected from backyard chicken eggs, as well as a range of comm…
CSEF · 2026
Biochemistry/ Molecular Biology (Senior Division)
α-synuclein aggregation is a hallmark of Parkinsonian disorders, where the normally flexible protein misfolds into β-sheet–rich fibrils that disrupt cells. Despite its importance, the specif…
CSEF · 2025
Biochemistry/ Molecular Biology First Award
CSEF · 2025
Biochemistry/ Molecular Biology Honorable_mention Award
CSEF · 2025
Biochemistry/ Molecular Biology Fourth Award
CSEF · 2025
Biochemistry/ Molecular Biology Second Award
CSEF · 2025
Biochemistry/ Molecular Biology Third Award
CSEF · 2025
Biochemistry/ Molecular Biology Honorable_mention Award
CSEF · 2025
Biochemistry/ Molecular Biology Fourth Award
CSEF · 2025
Biochemistry/ Molecular Biology Honorable_mention Award