11705 projects whose affiliated fair was here, most recently in 2026.
ISEF records a state or province for some finalists and not others, so these counts do not add up to the country total.
11705 projects · showing 511–540
ISEF · 2026
Animal Sciences
Morphogen gradients determine distinct cell fate within tissues, and it has previously been thought that the cells affected by this determination are static. However, cells usually move duri…
ISEF · 2026
Earth and Environmental Sciences
It's been hypothesized that carbonaceous chondrite meteorites can transport compounds crucial to planetary habitability. Meteorites generate hydrothermal systems through impact energy dissip…
ISEF · 2026
Biomedical and Health Sciences
Triple negative breast cancer is notoriously difficult to treat bacause it lacks estrogen receptors, progesterone receptors, and HER2 protein that drive the majority of breast cancers and th…
ISEF · 2026
Physics and Astronomy
Aerodynamics is heavily dependent on the four main forces of flight, weight, lift, thrust, and drag. Drag heavily impacts the aerospace industry's ability to create faster and more effective…
ISEF · 2026
Materials Science
This study investigates the environmental impact of petroleum-based plastics, which have created a demand for sustainable polymer alternatives. This study investigates the development of a b…
ISEF · 2026
Translational Medical Science
Lung cancer remains one of the leading causes of death worldwide. In 2026 in the United States, an estimated 124,990 people are expected to die from this disease. In Hawai?i, the situation i…
ISEF · 2026
Microbiology
Lactobacillus acidophilus produces lactase, an enzyme that hydrolyzes lactose into glucose and galactose, helping alleviate symptoms of lactose intolerance. However, the protective effects o…
ISEF · 2026
Plant Sciences
As Ambrosia artemisiifolia, an invasive weed species, expands its global presence, it generates significant yield losses of up to 50% in Zea mays L., destabilizing economies and altering soi…
ISEF · 2026
Chemistry
Biological molecules, such as DNA and RNA have a variety of pharmaceutical and medical applications and were heavily utilized within the creation of the Covid-19 vaccine. However, biological…
ISEF · 2026
Biochemistry
Silk fibroin is a sustainable biopolymer with extraordinary mechanical properties derived from its hierarchical self-assembly into ß-sheet nanostructures. Biological silk spinning leverages…
ISEF · 2026
Biochemistry
Ionizable lipid nanoparticles (LNPs) are the mainstream delivery mechanisms for mRNA vaccines, with their pH-sensitive protonation facilitating post-endocytic endosomal escape. However, LNPs…
ISEF · 2026
Mathematics
This project investigated a cryptographic framework for cybersecurity utilizing a pair of a field-defining monic irreducible polynomial f(x) and an associated multiplier polynomial k(x) as a…
ISEF · 2026
Engineering Technology: Statics & Dynamics
One of the largest contributors to today's CO2 emissions is personal urban commuting, the daily driving from one place to another, mainly from a home to a place of work. It is one of the lea…
ISEF · 2026
Software Design
Gaze keyboards require people with ALS to spell words one letter at a time, a process that is slow, exhausting, and forces users to translate simple thoughts into tedious typing sequences. E…
ISEF · 2026
Plant Sciences
Carnegiea gigantea (Saguaro cactus) plays a significant role both ecologically and culturally in the Sonoran Desert region of Arizona. However, this magnificent and unique cactus species fac…
ISEF · 2026
Computational Biology and Bioinformatics
Pancreatic ductal adenocarcinoma (PDAC) survives nutrient stress by rewiring metabolism. Prior ketogenic-diet (KD) evidence indicates increased TCA-cycle activity and higher glutamine (GLN)…
ISEF · 2026
Biomedical Engineering
Assistive grasping of slippery, delicate, or thin objects remains challenging for hand-impaired individuals. Current prosthetic hands and soft grippers often rely on rigid linkages or bulky…
ISEF · 2026
Physics and Astronomy
Binary neutron star (BNS) mergers emit gravitational waves and eject neutron-rich matter, powering a short-lived infrared transient known as a kilonova. Immediately after the merger, the hyp…
ISEF · 2026
Microbiology
Pseudomonas aeruginosa is prevalent in hospital-acquired pneumonia, with mortality reaching 70%, and chronic cystic fibrosis infections. The reason the anitbiotics don't work is the LasR quo…
ISEF · 2026
Biomedical and Health Sciences
Psychiatric disorders, including schizophrenia (SCZ) and bipolar disorder (BD), are leading causes of global disability. The development of effective therapeutics is challenged by the comple…
ISEF · 2026
Translational Medical Science
In rural areas of the world, such as villages in India & Africa, inhabitants lack access to medical infrastructure. Due to this, early disease diagnosis is not possible, as early symptoms fo…
ISEF · 2026
Cellular and Molecular Biology
This project aims to link the cellular heat stress response of Montipora capitata to its biological immortality. The amortality of this species is attributed to alternative methods of telome…
ISEF · 2026
Microbiology
Burkitt's Lymphoma is an aggressive B-cell malignancy associated with Epstein-Barr virus (EBV) infection. Over 95% of the world's population is persistently infected by EBV. While current tr…
ISEF · 2026
Biomedical and Health Sciences
Extracorporeal Membrane Oxygenation (ECMO) is a life-saving cardiopulmonary support system for patients with severe cardiac and/or respiratory failure. Its use has increased substantially si…
ISEF · 2026
Behavioral and Social Sciences
Benchmarks often fail to capture true large language model (LLM) trustworthiness, as models behave differently under evaluation than in real-world deployment. This research introduces a syst…
ISEF · 2026
Chemistry
The purpose of this experiment was to test the spread and droplet size of a drone application with and without a chemical surfactant adjuvant. It is hypothesized, the water with the chemical…
ISEF · 2026
Microbiology
CRISPR–Cas systems enable bacteria to defend against viral infection through RNA-guided nucleases and accessory proteins, though the functions of many accessory components remain unclear. Th…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Flash flooding is one of the deadliest weather events, taking over 5,000 lives each year. Traditional flash flood detection systems are often inadequate: they are expensive, require frequent…
ISEF · 2026
Biomedical Engineering
In 2025, the American Cancer Society reported 2.1 million Americans were diagnosed with cancer, which is the leading cause for 1 in 6 deaths. This can largely be attributed to late diagnoses…
ISEF · 2026
Materials Science
Despite its accessibility and geometric versatility, polymer additive manufacturing remains limited in industrial use due to the inherent structural and chemical vulnerabilities of polymers.…