Animal Sciences
Changes in temperature are known to have molecular effects on biological mechanisms. It has been found that when exposed to heat stress, Caenorhabditis elegans lose fertility and a general d…
Computational Biology and Bioinformatics
Genetic neurodegenerative diseases affect more than 57 million people worldwide. With aging populations, their prevalence is rising, making early prediction critical for enabling timely inte…
Translational Medical Science
Non-small cell lung cancer (NSCLC) accounts for 85% of all lung cancers and can develop resistance to current therapies. This creates an urgent need for more effective and targeted treatment…
Translational Medical Science
In rural areas of the world, such as villages in India & Africa, inhabitants lack access to medical infrastructure. Due to this, early disease diagnosis is not possible, as early symptoms fo…
Translational Medical Science
Background: Treatment of Multiple Myeloma (MM) with bispecific antibodies (bsAb) results in an increased risk of infection, and predicting this risk is a significant unmet need. Aim: Develop…
Physics and Astronomy
IC 4634 is a planetary nebula with a striking double-S shape, whose curved arcs and distant knots preserve a record of its outflow history. This study presents the first 3D morpho-kinematic…
Energy: Sustainable Materials and Design
As global energy demand rises, ocean waves remain an underutilized renewable energy source that carries significantly more energy per unit area than wind or solar and provides a more consist…
Engineering Technology: Statics & Dynamics
The IceCube Neutrino Observatory requires boreholes drilled 2,500 meters into the Antarctic ice sheet using a 5 megawatt hot water drill. During the first 66 minutes of drill startup insuffi…
Computational Biology and Bioinformatics
Alzheimer’s disease affects over 55 million people worldwide, making early prediction crucial for timely interventions to slow disease progression and improve quality of life. Single Nucleot…
Environmental Engineering
Since the invention of modern plastics during the 20th century, microplastics (MPs) have become one of the most pervasive anthropogenic pollutants on Earth—being found everywhere from the Ma…
Engineering Technology: Statics & Dynamics
The aerodynamic efficiency of an aircraft's nose cone is crucial to overall flight performance. Traditional nose cone designs are optimized for specific speed regimes, which limits their ove…
Biomedical and Health Sciences
Chimeric Antigen Receptor (CAR) T Cells and Bispecific T Cell Engagers (BiTEs) have revolutionized the treatment of relapsed/refractory hematologic cancers. However, there are no head-to-hea…
Translational Medical Science
Malaria is a devastating disease that kills over half a million people annually. Research shows the Plasmodium falciparum protozoan disrupts iron regulation by degrading ferroportin, allowin…
Cellular and Molecular Biology
Although CAR T-cell therapy has significantly improved treatment outcomes for hematologic B-cell malignancies, challenges such as relapse and mortality rates (35-50% within 6-12 months post-…
Physics and Astronomy
Accurately detecting exoplanets is essential for understanding planetary system formation and dynamics. Anomaly detection is an essential part of exoplanet studies, especially when analyzing…
Translational Medical Science
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease. Early diagnosis and efficient rehabilitation are critical, while current methods of in person clinical consul…
Biomedical and Health Sciences
Cancer has remained the leading cause of death globally, with the mutation of the Tumor Suppressor Gene TP53 via DNMT1 methylation occurring in 50% of cases. Current epigenetic therapies mis…
Biomedical Engineering
Parkinson's patients often encounter challenges like irregular finger tremors and stiffness. Recent research has underscored the potential benefits of rehabilitation training, crucial for re…
Computational Biology and Bioinformatics
Sequence alignment tools have traditionally been used to study the evolution of genome sequences by aligning sequences of varying lengths. However, these tools are memory-intensive, time-con…
Translational Medical Science
Fourth Award
I propose a method that enables the development of treatments for the 350 million people worldwide suffering from 7,000 rare genetic diseases. Genomic therapies for rare genetic diseases are…
Biochemistry
Fourth Award
Antimicrobial resistance(AMR) is a global health threat and the discovery of new antimicrobial compounds has been limited in the past four decades. New antimicrobials with new functions are…
Biomedical and Health Sciences
Chimeric Antigen Receptor (CAR) T cells and Bispecific T cell Engagers (BiTEs) are two novel immunotherapy platforms. I hypothesized that the different mechanisms used by anti-CD3-CD19 BiTEs…
Cellular and Molecular Biology
Natural Killer (NK) cells are an essential component of innate host defense against Hepatocellular Carcinoma (HCC). A central determinant of NK cell function is their tissue residency. I hyp…
Environmental Engineering
Fourth Award
Since the beginning of modern plastic's invention nearly a century ago, the human species as a whole has continually increased its rate of plastic consumption and waste. Until recently, this…
Energy: Sustainable Materials and Design
Dye-sensitized solar cells (DSSCs) offer solutions to the drawbacks of traditional silicon solar cells. However, research is needed to identify and harness factors that may increase their ef…
Materials Science
Playing sports such as soccer, baseball, or football on a hot and sunny day is always dreaded, especially when playing on synthetic turf. In August, turf temperatures in Madison, WI can be a…
Translational Medical Science
There is currently no definitive screening method or test for Parkinson’s Disease (PD), the second most prevalent neurodegenerative disorder with over 10 million cases worldwide and 1 millio…
Engineering Technology: Statics & Dynamics
First Award
Electric-vertical-takeoff-and-landing (eVTOL) aircraft could enable the implementation of large-scale Urban Air Mobility projects, thereby mitigating problems that currently face the transpo…
Microbiology
This experiment’s purpose was to analyze the direct relationship between the gut bacteria E. coli and L. acidophilus and the skin bacteria S. epidermidis. To begin, a preliminary trial was p…
Chemistry
Dissolved oxygen (DO) and temperature were measured in Lake Mendota at depths of 1, 10, and 20 meters on a weekly basis between June 9th and July 21st during the summer of 2022. Sampling was…