11705 projects whose affiliated fair was here, most recently in 2026.
ISEF records a state or province for some finalists and not others, so these counts do not add up to the country total.
11705 projects · showing 541–570
ISEF · 2026
Translational Medical Science
Pancreatic ductal adenocarcinoma (PDAC) ranks 10th in US cancer incidence, yet it causes more deaths per year than breast cancer, ranked 1st, a disparity largely driven by complications rega…
ISEF · 2026
Computational Biology and Bioinformatics
Autism spectrum disorder (ASD) is a neurodevelopmental condition affecting many areas of life. Resting-state functional MRI (rs-fMRI) measures functional connectivity between brain regions a…
ISEF · 2026
Translational Medical Science
Background: Treatment of Multiple Myeloma (MM) with bispecific antibodies (bsAb) results in an increased risk of infection, and predicting this risk is a significant unmet need. Aim: Develop…
ISEF · 2026
Cellular and Molecular Biology
Oral squamous cell carcinoma (OSCC) accounts for over 90% of oral cancers, with 5-year survival rates below 60% due to late-stage diagnosis. Current diagnostic approaches rely on invasive su…
ISEF · 2026
Materials Science
Metal-organic frameworks (MOFs) are highly tunable nanomaterials with potential in targeted immunotherapy and biological interfaces; however, the vast number of possible metal frameworks lim…
ISEF · 2026
Earth and Environmental Sciences
Known as the “rainforests of the sea” coral reefs support over 1 billion people. Yet the rising ocean temperatures have driven increasingly frequent coral bleaching events, threatening reefs…
ISEF · 2026
Animal Sciences
Neonatal Maladjustment Syndrome (NMS), also known as dummy calf syndrome, affects newborn calves by limiting their alertness, ability to stand, nurse, and bond with their mother. The researc…
ISEF · 2026
Materials Science
Slips, Trips, and Falls (STFs) are major sources of accidents among various populations. About 38 mill falls happen each year in the US alone, with more than 50,000 associated with mobility…
ISEF · 2026
Energy: Sustainable Materials and Design
Can you imagine clothing made from seaweed? The textile/fashion industry discards in excess of 90 tons of textile waste annually. The industry is trying to become more sustainable by develop…
ISEF · 2026
Translational Medical Science
Triple-negative breast cancer (TNBC) is one of the deadliest breast cancer subtypes because it lacks the receptors targeted by most therapies, leaving patients with few treatment options. Th…
ISEF · 2026
Software Design
Photodynamic Therapy (PDT) is a non-invasive treatment for esophageal, skin, and non-small-cell lung cancers that relies on light-activated drugs called photosensitizers to generate cytotoxi…
ISEF · 2026
Materials Science
Moon colonization would benefit from manufacturing using local materials such as moon dust, a basaltic volcanic ash (BVA). We investigate the feasibility of additive 3D printing (FDM) with a…
ISEF · 2026
Microbiology
Manuka honey is known for its antimicrobial properties, but it is unclear how heating affects its ability to inhibit bacterial growth. This experiment tested whether increasing the temperatu…
ISEF · 2026
Robotics and Intelligent Machines
In fields such as exploration or inspection in hazardous environments, the ability to navigate terrain safely is crucial. This is often done through robotics; however, traditional systems (r…
ISEF · 2026
Translational Medical Science
Diagnosing drug-resistant strains Mycobacterium tuberculosis (Mtb) is critical for informing treatment plans and limiting infections. However, existing diagnostics are slow and cover a narro…
ISEF · 2026
Physics and Astronomy
Purpose: Entanglement determines how quantum information is stored and processed, but measurements impact entanglement behavior in open quantum circuits. This project studies entanglement ph…
ISEF · 2026
Materials Science
This study investigates the effects of environmental temperature fluctuations and ultrasonic cleaning on the mechanical properties of two polymers: polyethylene terephthalate glycol (PETG) a…
ISEF · 2026
Computational Biology and Bioinformatics
Spinal Cord Injuries (SCI) generally cause permanent functional loss due to the accumulation of inhibitory molecules, such as chondroitin sulfate proteoglycans (CSPGs), synthesized by a mult…
ISEF · 2026
Biomedical and Health Sciences
Chemoresistance remains a primary cause of cancer treatment failure and is increasingly attributed to non-genetic regulatory mechanisms. Emerging evidence suggests that three-dimensional chr…
ISEF · 2026
Earth and Environmental Sciences
Nitrobenzene is a potential carcinogen, highly flammable, and toxic environmental pollutant in air, water, and soil that is commonly synthesized in pesticide, dye, and explosives manufacturi…
ISEF · 2026
Biomedical Engineering
As humanity ventures beyond Earth, the challenges of space travel extend beyond rocket science and astrophysics. Astronauts face extreme physiological stress, and during deep-space missions…
ISEF · 2026
Robotics and Intelligent Machines
Large language models (LLMs) are increasingly trusted in domains such as education, research, and decision making. Despite their widespread adoption, fundamental questions remain about align…
ISEF · 2026
Earth and Environmental Sciences
This experiment focuses on the effectiveness of metal oxide nanoparticle infused biochar in adsorbing heavy metals (Pb and Cd) from simulated runoff. The basis of this experiment is the surf…
ISEF · 2026
Robotics and Intelligent Machines
A significant number of bridges in the United States are susceptible to failure, and one of the main factors that causes failure is overload. Severe consequences can result from bridge failu…
ISEF · 2026
Biomedical Engineering
MicroMCED is designed to bring routine multicancer screenings to more people with an accessible point of care blood test. Current screening tests require expensive specialized equipment that…
ISEF · 2026
Earth and Environmental Sciences
This study investigated Martian soil and different way to enhance the soil for plants to grow on Mars because the soil on this planet is not able to support life let alone grow food. I teste…
ISEF · 2026
Behavioral and Social Sciences
The United States is linguistically diverse. Approximately 23% of individuals in the United States speak a language other than English at home. Of those same individuals, 61% speak Spanish.…
ISEF · 2026
Robotics and Intelligent Machines
Post-hoc domain generalization (PDG) methods aim to generalize machine learning models to unseen target domains using only source-domain information leveraged after training. Unlike train-ti…
ISEF · 2026
Energy: Sustainable Materials and Design
In the pursuit of sustainable energy, converting methane to hydrogen presents a vital pathway for mitigating greenhouse gas emissions. While methane is a potent feedstock, traditional reform…
ISEF · 2026
Cellular and Molecular Biology
KARS1 encodes bifunctional cytoplasmic and mitochondrial lysyl-tRNA synthetases, and biallelic loss-of-function variants cause infantile-onset progressive leukoencephalopathy (LEPID) and rel…