20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2026
Plant Sciences
Modern agriculture faces two challenges: managing agro-industrial waste and reducing reliance on synthetic agrochemicals. The integration of materials science and agricultural biotechnology…
ISEF · 2026
Environmental Engineering
Widespread contamination of surface and groundwater systems from heavy metals, excess nutrients, and other hazardous pollutants has intensified the need for sustainable water remediation tec…
ISEF · 2026
Computational Biology and Bioinformatics
Systemic inflammatory diseases like cirrhosis, ankylosing spondylitis (AS), and hypertension affect over 1 billion people and are often detected after significant organ damage. Growing evide…
ISEF · 2026
Cellular and Molecular Biology
Glioblastoma multiforme (GBM) is one of the most aggressive and rapidly progressing brain tumors. Due to its molecular heterogeneity, it exhibits strong resistance to therapy. Recent studies…
ISEF · 2026
Plant Sciences
Abiotic stresses reduce global crop yields by up to 70%, threatening global food security. While stress-responsive pathways are well studied, the role of deubiquitination in plant developmen…
ISEF · 2026
Biomedical and Health Sciences
Parkinson's disease is a progressive neurodegenerative disorder requiring early intervention, yet screening is often delayed due to a dependency on expensive, in-person clinical assessments.…
CWSF · 2026
Environment & Climate Change Silver Medal
I am working to create a biodegradable alternative that could help replace plastic because I am worried about the effects of plastics, particularly microplastics on animals, human health, an…
ISEF · 2026
Cellular and Molecular Biology
Alzheimer's disease is a neurodegenerative disorder characterized by loss of matter in the brain driven by amyloid-ß (Aß) aggregation. In scientific literature, the role of inhibitory neurot…
ISEF · 2026
Technology Enhances the Arts
This project determined if playing different games in different amounts would affect typing speed and accuracy. The experiment was performed due to personal research that showed an increase…
ISEF · 2026
Biochemistry
Breast cancer remains the most prevalent malignancy among women worldwide. Dose-dense AC-T chemotherapy (Adriamycin, Cyclophosphamide, and Paclitaxel), a commonly prescribed regimen, is asso…
ISEF · 2026
Environmental Engineering
Polyethylene terephthalate (PET) is one of the most common plastics used worldwide, and is used to create products like water bottles, food packaging, and textiles. PET is difficult to break…
ISEF · 2026
Physics and Astronomy
Photonic devices—engineered systems composed of metal-dielectric nanostructures—provide a powerful platform for manipulating and probing the quantum properties of light. These systems suppor…
ISEF · 2026
Computational Biology and Bioinformatics
Brain cancer, or glioblastoma, is one of the most aggressive cancers, given the nutrient-dense environment of the brain. This cancer is very deadly, given the significance of the brain for t…
CYSF · 2026
We are aiming to create a triboelectric nanogenerator that can generate electricity from snow to help energy poverty in secluded countries.
ISEF · 2026
Biochemistry
Oligonucleotides, especially siRNAs, have been identified as a point of interest in recent research due to their capability for targeting of “undruggable” targets. siRNAs bind to and guide t…
ISEF · 2026
Computational Biology and Bioinformatics
Autism Spectrum Disorder (ASD) exhibits substantial heterogeneity in long-term developmental outcomes. Children with similar early symptoms often follow divergent cognitive and adaptive-func…
ISEF · 2026
Cellular and Molecular Biology
Nonalcoholic fatty liver disease is characterized by excessive lipid accumulation in the liver and can progress to nonalcoholic steatohepatitis, fibrosis, cirrhosis, and hepatocellular carci…
ISEF · 2026
Plant Sciences
Global warming has led to a significant escalation of the rate of coral bleaching, with 90% of reefs projected to experience bleaching annually by 2050. Coral bleaching often occurs when mar…
ISEF · 2026
Cellular and Molecular Biology
Besides the familiar double helix, DNA can form alternative structures such as G-quadruplexes (G4), guanine-rich four-stranded structures that arise during replication and repair. G4s are co…
ISEF · 2026
Robotics and Intelligent Machines
Autonomous robots rely on Simultaneous Localization and Mapping (SLAM) to build maps and estimate their position within unknown environments. While many modern robotic systems achieve high r…
ISEF · 2026
Mathematics
Gerrymandering is the process when congressional district maps are redrawn to benefit a certain political party. This process undermines democracy while giving disproportionate advantage to…
CYSF · 2026
Using a self-made equation to model a household as either low, average, or high greywater producer, further explaining the best method of greywater reuse for an individual household.
ISEF · 2026
Software Design
Plant diseases, particularly fungal infections, cause significant crop losses worldwide due to delayed detection and limited access to rapid diagnostic tools. This project presents Gharsa, a…
CWSF · 2026
Aerospace Gold Medal
The nature of dark matter (DM) remains one of the biggest unanswered questions in physics, all while current methods remain challenged with accurately distinguishing between different DM mod…
ISEF · 2026
Biomedical Engineering
Migraines are a debilitating neurological condition that impacts over one billion people across the globe, but not enough research or developments on the treatment of migraines have been don…
ISEF · 2026
Biomedical Engineering
Gut motility disorders affect over 20% of the population, but standard diagnostic tools, including endoscopy and manometry, are invasive, expensive, limited to clinical settings, and don’t t…
ISEF · 2026
Biomedical and Health Sciences
Nerve degeneration causes devastating symptoms for millions of patients worldwide. While some peripheral nerves experience recovery, others experience chronic neuropathic pain due to sensory…
ISEF · 2026
Biomedical and Health Sciences
Impaired wound healing is a widespread complication experienced by diabetic patients, with persistent hyperglycemic conditions being a central factor that disrupts cellular repair programs.…
ISEF · 2026
Computational Biology and Bioinformatics
Despite decades of therapeutic development, most disease-associated proteins remain therapeutically inaccessible. These so-called “undruggable” targets typically lack suitable binding pocket…
ISEF · 2026
Mathematics
The Monty Hall problem refers to a question that was asked in the television game, “Let’s Make a Deal”, whose host is Monty Hall. In this question a contestant chooses between three doors, o…