Browse real student projects, abstracts, and awards.
ISEF · 2025
Animal Sciences
Traditional nesting boxes fail to replicate the stable microclimate of natural tree hollows crucial for mature tree species, due to offset designs causing large temperature fluctuations, lea…
ISEF · 2025
Microbiology
Antibiotic resistance is a rising threat to public health. Until recent years, efforts to combat antibiotic resistance have focused on creating newer and stronger antibiotics, but pathogens…
ISEF · 2025
Computational Biology and Bioinformatics
Drug-drug synergy is crucial for developing effective combination therapies, and gene function relationships play an important role in identifying these synergies. However, due to the comple…
ISEF · 2025
Cellular and Molecular Biology
In vitro drug sensitivity testing is critical for identifying effective cancer treatments. However, due to the vast number of potential drug monotherapies and combination therapies, in vitro…
ISEF · 2025
Behavioral and Social Sciences
The purpose of this study is to isolate the specific population of an all-girls, private, Catholic high school to determine the effects of school climate on mental wellbeing of teachers and…
ISEF · 2025
Behavioral and Social Sciences
Native Hawaiian and Pacific Islanders (NHPI) suffer disproportionately from cardiometabolic health conditions, with diabetes mortality rates 3.32 times higher than the general population, ye…
ISEF · 2025
Embedded Systems
The design of flat metasurfaces is crucial for innovations in LiDAR, AR and optical imaging. Recent advances in flat metasurface optics have enabled precise light manipulation, overcoming tr…
ISEF · 2025
Materials Science
The global water crisis affects over 2 billion people, with contaminated water sources leading to waterborne diseases and the growing threat of antimicrobial resistance (AMR). This challenge…
ISEF · 2025
Computational Biology and Bioinformatics
Globally, countless organisms suffer from infections, diseases, and environmental threats. Custom proteins are at the heart of solutions to these challenges. Custom proteins are life-saving…
ISEF · 2025
Biomedical and Health Sciences
Duchenne Muscular Dystrophy (DMD) is a severe genetic condition that causes progressive muscle weakness and degeneration. Despite current treatments focusing on symptom management, no cure e…
ISEF · 2025
Technology Enhances the Arts
Globally, an estimated 40-45 million people are blind, and an estimated 160 million are affected by deafness and blindness. Those who can hear can rely on speech to learn and communicate, wh…
ISEF · 2025
Translational Medical Science
Despite the fact that studies have established a notable link between tourism-particularly cruise ship traffic-and increased respiratory illnesses, there is a lack of official research exami…
ISEF · 2025
Cellular and Molecular Biology
Central nervous system (CNS) diseases such as Alzheimer's, epilepsy, and stroke affect over 1 billion people globally, and dysregulated astrocytic calcium signaling can drive these pathologi…
ISEF · 2025
Biochemistry
Herpes Simplex Virus-1 (HSV-1) infects around 70% of the global population, causing cold sores on the lips and genitals. This study presents a novel antiviral approach targeting plakin prote…
ISEF · 2025
Behavioral and Social Sciences
WHO states that the global life expectancy (LE) is 73 years, with chronic diseases responsible for 75% of all deaths globally. Beyond individual wellbeing, this reality places substantial bu…
ISEF · 2025
Robotics and Intelligent Machines
Cocoa production contributes 10% to Ghana’s GDP, but diseases like Anthracnose and Cocoa Swollen Shoot Virus Disease (CSSVD) caused $1.2 billion in losses in 2023. Traditional detection meth…
ISEF · 2025
Behavioral and Social Sciences
In many scenarios, from democratic governance to decision-making in corporate boards and international organizations, voting plays a crucial role. However, not all votes carry the same weigh…
ISEF · 2025
Microbiology
This study investigates how per- and polyfluoroalkyl compounds—PFOA, PFOS, and PFBA—affect the growth and genetic stability of Saccharomyces cerevisiae, a eukaryotic organism with a genome t…
ISEF · 2025
Animal Sciences
This project tracked intestinal parasites in stray feline populations on Oahu to assess severity of the presence of parasites in the environment with posed zoonotic risks. Using fecal flotat…
ISEF · 2025
Robotics and Intelligent Machines
Urban transportation faces multifaceted challenges including traffic congestion, road safety, and the need for real-time accident prevention. This project presents a comprehensive approach e…
ISEF · 2025
Translational Medical Science
Thyroid cancer (TC) is one of the most common endocrine malignancies worldwide, with 821,214 newly diagnosed cases in 2022. It has the fastest growth rate across all cancers. Despite its pre…
ISEF · 2025
Cellular and Molecular Biology
Introduction: Pancreatic ductal adenocarcinoma (PDA) remains one of the deadliest malignancies due to late diagnosis, extensive metastasis, and limited treatment options. A multifunctional g…
ISEF · 2025
Earth and Environmental Sciences
Greenhouse gases, with carbon dioxide (CO2) being the most significant contributor, are the primary causes of climate change. Atmospheric CO2 levels have risen dramatically from pre-industri…
ISEF · 2025
Chemistry
The Ultraviolet Index (UVI) is a measure of the likelihood of getting sunburned while outside. Its only limitation is that the UVI is entirely predicted by satellites and is not measured at…
ISEF · 2025
Energy: Sustainable Materials and Design
Hydrogel polymer electrolytes (HPEs) have gained considerable popularity in energy storage. Hydrogels are hydrophilic polymeric networks that can be extended multi-dimensionally via cross-li…
ISEF · 2025
Physics and Astronomy
NASA aims to send humans to Mars by the 2030s-2040s. A leading scientific goal will be the search for signs of indigenous life, past or present, which if found, would have major implications…
ISEF · 2025
Earth and Environmental Sciences
This project assessed whether pine tree ring growth could be used to track rates of saltwater intrusion by analyzing pine tree growth ring response to surface water specific conductance leve…
ISEF · 2025
Biomedical Engineering
Parkinson's Disease (PD) is a neurodegenerative disease estimated to affect around 1 million people in the US. It is also the fastest growing neurodegenerative disease with growth rates comp…
ISEF · 2025
Animal Sciences
Non-native species pose a global threat to aquatic ecosystems, with the potential to spread rapidly, reduce biodiversity, and induce ecological changes. The globally distributed Australian t…
ISEF · 2025
Plant Sciences
A local problem in Florida is the immense expense of fertilizing golf courses, reaching over $100,000 annually. A global problem involves the disposal of biosolids from wastewater treatment…