Browse 17,565 real projects from ISEF, with abstracts, awards and links to the original entries.
ISEF · 2026
Translational Medical Science
Breast cancer is the leading cause of cancer-related death among women, with approximately 42,000 deaths annually in the United States and over 700,000 worldwide. Brain metastases represent…
ISEF · 2026
Biomedical Engineering
Deeper superficial abrasions or wounds that extend into the dermis often require intensive treatment to prevent complications such as infection, pain, and delayed healing. In these cases, sk…
ISEF · 2026
Behavioral and Social Sciences
Major depressive disorder (MDD) affects over 332 million people worldwide and is a leading cause of disability. Duloxetine is a widely prescribed antidepressant; however, discontinuation is…
ISEF · 2026
Earth and Environmental Sciences
With 2.25 million tons of annual flame retardant production, phosphorus flame retardants cause aquatic ecosystem disruption and eutrophication. Agricultural waste disposal causes 6% of globa…
ISEF · 2026
Environmental Engineering
This year’s engineering project targeted to expand the BioRegen prototype, a waste-derived plastic-alternative optimized for natural biodegradation and performance. The development of a prot…
ISEF · 2026
Computational Biology and Bioinformatics
Mapping long - range axonal projections is critical for understanding neural circuit dysfunction in neurodegenerative diseases. While machine learning ( ML ) tools have advanced volumetric c…
ISEF · 2026
Technology Enhances the Arts
Bilingual children are frequently misdiagnosed in schools and clinics because speech patterns shaped by second-language acquisition can resemble speech sound disorders. As a result, a typica…
ISEF · 2026
Computational Biology and Bioinformatics
Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults, with ~22,000 new cases and ~11,000 deaths in the USA annually. AML subtypes require distinct treatment proto…
ISEF · 2026
Energy: Sustainable Materials and Design
Sargassum buildup along the coasts has raised environmental concerns and spurred research into its potential as a renewable energy source. This study examines how reaction time influences bi…
ISEF · 2026
Environmental Engineering
Plastic pollution and microplastics are major environmental concerns, especially in the healthcare industry, which relies heavily on single use plastics. This project investigated whether bi…
ISEF · 2026
Environmental Engineering
Devices placed on the seabed in shallow coastal waters must remain stable under waves and near-bed currents. In this project, I developed a coastal underwater seabed waste bin that serves as…
ISEF · 2026
Translational Medical Science
Neurodegenerative diseases like Alzheimer's affect millions worldwide, yet current diagnostic methods remain invasive, expensive, and largely inaccessible during the critical early intervent…
ISEF · 2026
Earth and Environmental Sciences
Coral bleaching is a harmful phenomenon where corals expel their symbiotic algae called zooxanthellae caused by global warming induced environmental stressors. Conservation efforts utilize p…
ISEF · 2026
Animal Sciences
Asian elephant (Elephas maximus) groups exhibit a fission-fusion social structure, temporarily separating and reuniting multiple times throughout an elephant’s life. Due to this social dynam…
ISEF · 2026
Biomedical Engineering
Despite the availability of digital assistive technology, visually impaired adults often use traditional printed medication labels, which hinder independent identification of medications. Co…
ISEF · 2026
Animal Sciences
In North America, solitary bees are primary pollinators for a variety of commercial crops and native plants. Habitats have dwindled over time due to nonnative grass lawns and pesticide use.…
ISEF · 2026
Mathematics
Gerrymandering poses a significant threat to American democracy. Current identification methods, e.g. Polsby-Popper and Reock scores are highly sensitive to physical geography and unreliable…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Crosswind poses a significant and unavoidable threat to flight safety. Aircraft with elliptical annular wings have been proposed to possess inherent advantages for operations in strong cross…
ISEF · 2026
Chemistry
The healthcare and pharmaceutical sectors play a critical role in combating various diseases affecting human and societal life. One of the diseases affecting many people today is tinea skin…
ISEF · 2026
Chemistry
Environmental contaminants, particularly bisphenols, have become increasingly widespread. As a result, global water pollution has become of greater concern. Water pollution has a profound ef…
ISEF · 2026
Engineering Technology: Statics & Dynamics
In the context of modern aviation, aerodynamic efficiency and reduced fuel consumption are critical priorities. Nowadays, modern airliners travel relatively close to the speed of sound (Mach…
ISEF · 2026
Biochemistry
Papain enzyme is used in various industries such as food processing, medicine, environmental treatment and other applications but the high cost limits its industrial utility. A common way in…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Aircraft wings are typically optimized for limited operating conditions and rely on hinged control surfaces to modify aerodynamic performance. This engineering research investigated whether…
ISEF · 2026
Embedded Systems
In the private-led “New Space” era, orbital launch attempts have surged by 186% over the past decade, yet the ability to independently reach orbit remains severely restricted to wealthy nati…
ISEF · 2026
Robotics and Intelligent Machines
The $191.3 billion U.S. infrastructure repair backlog and unreliability of traditional manual visual inspections, which miss up to 94% of cracks, demonstrates the urgent need for improved in…
ISEF · 2026
Physics and Astronomy
In quantum photonic systems, information can be encoded in the distribution of photons (Fock states) across sites at a time. This makes it important to have control mechanisms that guide pho…
ISEF · 2026
Mathematics
Currently, seqNMF is the leading algorithm for extracting repeated temporal motifs from neuronal recordings. However, it is computationally expensive, requiring manual regularization tuning…
ISEF · 2026
Environmental Engineering
Over the last decade, more than 140 new emerging pollutants have been identified in wastewater treatment effluents, placing stress on existing infrastructure. These emerging pollutants inhib…
ISEF · 2026
Materials Science
Optoelectronic semiconductors are a critical part of modern technologies, yet 50% of failures are linked to thermal overload. Conventional semiconductor packaging processes employ a single e…
ISEF · 2026
Software Design
This research aims to address the high prevalence of obesity and diabetes in American Samoa by developing a deep learning–based food recognition system tailored to local dietary habits. The…