Browse real student projects, abstracts, and awards.
ISEF · 2026
Materials Science
This study investigates the environmental impact of petroleum-based plastics, which have created a demand for sustainable polymer alternatives. This study investigates the development of a b…
ISEF · 2026
Translational Medical Science
Lung cancer remains one of the leading causes of death worldwide. In 2026 in the United States, an estimated 124,990 people are expected to die from this disease. In Hawai?i, the situation i…
ISEF · 2026
Microbiology
Lactobacillus acidophilus produces lactase, an enzyme that hydrolyzes lactose into glucose and galactose, helping alleviate symptoms of lactose intolerance. However, the protective effects o…
ISEF · 2026
Plant Sciences
As Ambrosia artemisiifolia, an invasive weed species, expands its global presence, it generates significant yield losses of up to 50% in Zea mays L., destabilizing economies and altering soi…
ISEF · 2026
Plant Sciences
Gymnopodium floribundum (Dzidzilché) is a tree species of strategic importance for apiculture in the Yucatán Peninsula, a region that produces 35% of Mexico’s national honey output. Despite…
ISEF · 2026
Plant Sciences
Fusarium species are plant pathogens that reduce crop yields and contaminate food with harmful mycotoxins. Because long-term reliance on chemical fungicides can lead to resistance and enviro…
ISEF · 2026
Chemistry
Biological molecules, such as DNA and RNA have a variety of pharmaceutical and medical applications and were heavily utilized within the creation of the Covid-19 vaccine. However, biological…
ISEF · 2026
Biochemistry
Silk fibroin is a sustainable biopolymer with extraordinary mechanical properties derived from its hierarchical self-assembly into ß-sheet nanostructures. Biological silk spinning leverages…
ISEF · 2026
Biochemistry
Ionizable lipid nanoparticles (LNPs) are the mainstream delivery mechanisms for mRNA vaccines, with their pH-sensitive protonation facilitating post-endocytic endosomal escape. However, LNPs…
ISEF · 2026
Software Design
Severe Speech and Motor Impairment (SSMI), including conditions like advanced-stage ALS, progressively traps individuals in their bodies. This loss of muscle control and communication abilit…
ISEF · 2026
Mathematics
This project investigated a cryptographic framework for cybersecurity utilizing a pair of a field-defining monic irreducible polynomial f(x) and an associated multiplier polynomial k(x) as a…
ISEF · 2026
Engineering Technology: Statics & Dynamics
One of the largest contributors to today's CO2 emissions is personal urban commuting, the daily driving from one place to another, mainly from a home to a place of work. It is one of the lea…
ISEF · 2026
Translational Medical Science
Every year, 795,000 people die or suffer permanent disability — not from untreatable disease, but from a missed diagnosis. A patient takes a common painkiller alongside a daily prescription,…
ISEF · 2026
Software Design
Gaze keyboards require people with ALS to spell words one letter at a time, a process that is slow, exhausting, and forces users to translate simple thoughts into tedious typing sequences. E…
ISEF · 2026
Plant Sciences
Carnegiea gigantea (Saguaro cactus) plays a significant role both ecologically and culturally in the Sonoran Desert region of Arizona. However, this magnificent and unique cactus species fac…
ISEF · 2026
Microbiology
The global rise in bacterial resistance has spurred the exploration of natural alternatives with potential antimicrobial activity, including Kalanchoe pinnata, a plant traditionally used for…
ISEF · 2026
Biomedical and Health Sciences
Organophosphate (OP) exposure affects millions worldwide due to life-threatening and possibly irreversible symptoms. Neurological injury often persists after treatment, suggesting non-cholin…
ISEF · 2026
Biomedical Engineering
Breast cancer is the most commonly diagnosed cancer worldwide, yet 2.3 billion women lack access to screening due to the prohibitive cost of commercial computer-aided detection systems (~$50…
ISEF · 2026
Software Design
The efficiency of student learning is often hindered by complex academic tracking systems that prioritize administrative needs over student clarity. This project developed KazLib, a digital…
ISEF · 2026
Robotics and Intelligent Machines
Large language models (LLMs) achieve remarkable performance on complex reasoning tasks, yet they fail unpredictably and with high confidence on seemingly simple problems, posing a critical c…
ISEF · 2026
Computational Biology and Bioinformatics
Pancreatic ductal adenocarcinoma (PDAC) survives nutrient stress by rewiring metabolism. Prior ketogenic-diet (KD) evidence indicates increased TCA-cycle activity and higher glutamine (GLN)…
ISEF · 2026
Software Design
Twelfth grade students frequently encounter challenges related to their academic performance, which could be due to limited study strategies and ineffective learning habits. KeyserKat aims t…
ISEF · 2026
Chemistry
Acute kidney injury (AKI) affects over 13.3 million people annually, yet early diagnosis remains difficult because renal damage often develops subclinically before overt dysfunction becomes…
ISEF · 2026
Technology Enhances the Arts
Kintsugi is a traditional Japanese restoration technique for repairing broken objects, making them more beautiful and cherished over time. Rather than hiding damage, kintsugi highlights repa…
ISEF · 2026
Biomedical Engineering
Assistive grasping of slippery, delicate, or thin objects remains challenging for hand-impaired individuals. Current prosthetic hands and soft grippers often rely on rigid linkages or bulky…
ISEF · 2026
Physics and Astronomy
Binary neutron star (BNS) mergers emit gravitational waves and eject neutron-rich matter, powering a short-lived infrared transient known as a kilonova. Immediately after the merger, the hyp…
ISEF · 2026
Software Design
Culinary recipes are complex, semi-structured objects that combine a mix of language, nutrients, steps, and much more to define how a food item should be prepared. Since this can be difficul…
ISEF · 2026
Microbiology
Pseudomonas aeruginosa is prevalent in hospital-acquired pneumonia, with mortality reaching 70%, and chronic cystic fibrosis infections. The reason the anitbiotics don't work is the LasR quo…
ISEF · 2026
Plant Sciences
Pollution and dust accumulation are a growing global concern. Researchers are using several engineering and biological methods to mitigate and combat dust pollution. However, the methods nee…
ISEF · 2026
Plant Sciences
Whether plants—which lack a nervous system—can exhibit "intelligent" behaviors such as learning and stimulus discrimination remains a fundamental question in biology. I addressed this questi…