Browse 147 real Chemistry projects entered in 2026, with abstracts, awards and links to the original entries.
ISEF · 2026
Chemistry Second Award
The healthcare and pharmaceutical sectors play a critical role in combating various diseases affecting human and societal life. One of the diseases affecting many people today is tinea skin…
ISEF · 2026
Chemistry Second Award
Environmental contaminants, particularly bisphenols, have become increasingly widespread. As a result, global water pollution has become of greater concern. Water pollution has a profound ef…
ISEF · 2026
Biochemistry
Papain enzyme is used in various industries such as food processing, medicine, environmental treatment and other applications but the high cost limits its industrial utility. A common way in…
ISEF · 2026
Chemistry Third Award
Conventional methanol production relies on a two-step process, where carbon dioxide is first converted into synthesis gas (syngas) and then methanol. This syngas step requires increased ener…
ISEF · 2026
Biochemistry
Water pollution by phenolic compounds and heavy metals poses a significant threat to aquatic ecosystems, creating a need for rapid, low-cost methods to assess environmental toxicity. Tyrosin…
CSEF · 2026
Chemistry (Senior Division)
Cyclopropanes are important motifs found in natural products, commercial insecticides, and pharmaceutical compounds. However, their synthesis often relies on concerted reactions that limit m…
ISEF · 2026
Chemistry Fourth Award
Industrial wastewaters from gold mining and other industries often contain highly toxic cyanide-based compounds that threaten ecosystems and human health. This project bibliographically inve…
ISEF · 2026
Biochemistry
The main feature of cancer is that the cell's normal metabolic process has changed to allow for uncontrolled growth. Monocarboxylate transporter 2 (MCT2, encoded by SLC16A7) is responsible f…
ISEF · 2026
Biochemistry
It is crucial that cancer patients receive the proper medication dosage. Too high of a dose can be toxic; too low of a dose will not effectively kill cancer cells. Accurate dosing requires a…
ISEF · 2026
Chemistry
The blood-brain barrier (BBB) remains a formidable challenge in pharmacology, blocking ~98% of small-molecule drugs from entering the central nervous system (CNS). To address this challenge,…
ISEF · 2026
Chemistry
Chiral cyclopropanes are privileged structural motifs in pharmaceutical chemistry, essential for enhancing the potency and metabolic stability of therapeutics, including next generation anti…
ISEF · 2026
Biochemistry
Interactomes provide a framework for understanding the interactions that dictate biological processes. A well-constructed interactome allows for better disease understanding; however, tradit…
ISEF · 2026
Biochemistry
Neurodegenerative diseases such as Parkinson's & Alzheimer's are increasing worldwide exponentially. While many studies focus on factors such as aging & genetics, the effects of environmenta…
ISEF · 2026
Biochemistry
PFOA (Perfluorooctanoic acid), a type of PFAS (per- and polyfluoroalkyl substances), is a chemical used in the manufacturing of many products. PFOA is classified as an IARC Group 1 carcinoge…
ISEF · 2026
Biochemistry
Purpose: Drug overdoses have become a public health crisis in the United States, with approximately 68% involving opioids, particularly synthetic opioids such as fentanyl. Because overdose c…
CSEF · 2026
Chemistry (Junior Division)
My interest in chemistry and crystal-structures brought me to a recent abstract discussing adding salt in an attempt to enhance the crystal growth of large, organic molecules. From this I hy…
ISEF · 2026
Chemistry
This study aimed to address the recovery and reusability limitations of conventional homogeneous catalysts. For this purpose, zirconium-based metal–organic frameworks (MOFs) were synthesized…
ISEF · 2026
Chemistry Third Award
With the rapid expansion of lithium-ion batteries (LIBs) to EV cars and modern-day electronics, battery waste is projected to reach 8 million tons by 2040. Current recycling approaches, enco…
CSEF · 2026
Chemistry (Senior Division) Honorable_mention Award
The main purpose of this research project is to analyze the relative abilities of different varieties of biochar in chemically filtering water for populations in developing nations. Produced…
ISEF · 2026
Chemistry
The thermal decomposition of magnesium ammonium phosphate hexahydrate (MAP), a fertilizer recovered from wastewater, was investigated to identify reaction conditions that prevent ammonia los…
CSEF · 2026
Chemistry (Senior Division)
Honeybees face increasing stress from pesticide exposure, parasites, and poor nutrition, while honey is among the most frequently adulterated foods worldwide. This project investigates how p…
ISEF · 2026
Chemistry
Demand for energy to power industrial processes continues to increase in modern society, leading to increased carbon dioxide emissions into the atmosphere as a byproduct of burning fossil fu…
ISEF · 2026
Biochemistry
Hepatocellular carcinoma (HCC) is one of the world's leading cancer-related mortalities. In Vietnam, HCC ranks second in cancer incidence and accounts for more than 25,000 deaths annually. T…
CSEF · 2026
Chemistry (Junior Division)
The purpose of this experiment is to test how the temperature of the water mixed in the luminol compound affects the amount of light produced in the luminol reaction. This mixture is used ve…
CSEF · 2026
Chemistry (Junior Division)
In this experiment, I tested how much chemical energy is available in different foods by measuring the heat released while the food items burned. The temperature change of the water was reco…
ISEF · 2026
Biochemistry
Around 40.8 million people are living with HIV at the end of 2024 (World Health Organization, 2024). Around 630,000 deaths were due to HIV-related causes. These numbers highlight the need fo…
CSEF · 2026
Chemistry (Senior Division)
Design and Testing of a Chlorine-Neutralizing Shampoo Edrea Banh / Noman Sangar / Rachel Wagner / Danyelle Forte Sheldon High School Biotechnology Academy Chlorine exposure in recreational a…
ISEF · 2026
Chemistry Fourth Award
Traditional “best-before” dates on packaged meat are often rough estimates that do not take real storage conditions into account which can increase the risk of consuming spoiled food, posing…
ISEF · 2026
Biochemistry Fourth Award
Metastatic triple negative breast cancer (TNBC) is the most aggressive form of breast cancer, with a 5-year survival rate of 12%. Mesenchymal quadruple negative breast cancer (QNBC) is a mol…
CSEF · 2026
Chemistry (Senior Division)
My name is Carlos Sanchez, I go to Bakersfield High School which is located in the Kern high school district and my project is the computational optimization of Nitrogen found in agricultura…