38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
CSEF · 2026
Medicine & Physiology (Senior Division)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by mitochondrial dysfunction, impaired protein clearance, and accumulation of pathological aggregates. Anal…
ISEF · 2026
Biomedical and Health Sciences
Extracorporeal Membrane Oxygenation (ECMO) is a life-saving cardiopulmonary support system for patients with severe cardiac and/or respiratory failure. Its use has increased substantially si…
AJAS · 2026
Biomedical and Health Sciences (inferred)
Alzheimer’s Disease (AD) is an incurable neurodegenerative disease (NDD) that affects ~11% of adults over the age of 65. AD, like many other NDDs, is characterized by a buildup of misfolded…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Background/Objectives: Individuals with arrhythmia who survived COVID-19 could be susceptible to long-term cardiovascular complications and clinical outcomes. Methods: We performed a retrosp…
ISEF · 2026
Translational Medical Science
Pancreatic ductal adenocarcinoma (PDAC) ranks 10th in US cancer incidence, yet it causes more deaths per year than breast cancer, ranked 1st, a disparity largely driven by complications rega…
ISEF · 2026
Translational Medical Science
Background: Treatment of Multiple Myeloma (MM) with bispecific antibodies (bsAb) results in an increased risk of infection, and predicting this risk is a significant unmet need. Aim: Develop…
ISEF · 2026
Translational Medical Science
Abstract Parkinson's disease often affects voice and speech years before motor symptoms become clinically evident, and clinical diagnosis can take years to confirm. Machine learning applied…
ISEF · 2026
Translational Medical Science
The purpose of this investigation was to develop a machine learning model capable of predicting early vocal patterns associated with glottic carcinoma risk using acoustic biomarkers and life…
CWSF · 2026
Disease & Illness Bronze Medal
When someone is depressed, doctors prescribe antidepressant medication, but it only works for about half of patients, meaning the other half can wait months on ineffective treatment. We deve…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Annually, 20 million people are diagnosed with cancer, contributing to over 9.7 million deaths. Nearly 25% of these cases are linked to mutations in the KRAS gene, which normally functions a…
CWSF · 2026
Disease & Illness Silver Medal
Worldwide, medical problems in tubular organs, including emboli in blood vessels and foreign objects in the digestive tract, remain major threats to human health, while current surgical trea…
ISEF · 2026
Translational Medical Science Third Award
Triple-negative breast cancer (TNBC) is one of the deadliest breast cancer subtypes because it lacks the receptors targeted by most therapies, leaving patients with few treatment options. Th…
CSEF · 2026
Medicine & Physiology (Senior Division)
The nucleus tractus solitarius (NTS) and the spinal cord are important sensory hubs that project interoceptive and somatosensory information to similar brain regions, respectively; however,…
CSEF · 2026
Medicine & Physiology (Junior Division)
Pregnancy complications drive approximately 13.4 million preterm births globally each year and contribute to roughly 900,000 preventable neonatal deaths from conditions such as preeclampsia,…
ISEF · 2026
Translational Medical Science Third Award
Diagnosing drug-resistant strains Mycobacterium tuberculosis (Mtb) is critical for informing treatment plans and limiting infections. However, existing diagnostics are slow and cover a narro…
AJAS · 2026
Biomedical and Health Sciences (inferred)
1 in 5 individuals develops cancer in their lifetime. Due to treatment inefficiency, cancer is the leading cause of death worldwide. Unraveling immune cell-cancer cell interplay in the tumor…
ISEF · 2026
Biomedical and Health Sciences Second Award
Chemoresistance remains a primary cause of cancer treatment failure and is increasingly attributed to non-genetic regulatory mechanisms. Emerging evidence suggests that three-dimensional chr…
AJAS · 2026
Biomedical and Health Sciences (inferred)
Cervical cancer remains a major public health concern, with disparities in incidence and mortality disproportionately affecting non-Latine (nL) Black women. Diabetes has been implicated in c…
CWSF · 2026
Disease & Illness
Hepatitis C Virus (HCV) is a high mortality disease identified as one of the Top 10 eradicable global diseases. In Alberta, there are about 19,000 HCV patients, with 50 -75% being undiagnose…
CWSF · 2026
Health & Wellness Bronze Medal
With a growing and aging population taking an increasing number of prescription medications every year, adverse drug reactions are becoming increasingly common. Despite this, most clinical d…
CSEF · 2026
Medicine & Physiology (Senior Division)
This project investigated how dietary macronutrients affect the rate of glucose diffusion across a semi-permeable membrane. The hypothesis was that fiber and protein would reduce glucose dif…
ISEF · 2026
Biomedical and Health Sciences Second Award
Food allergy (FA) affects 18% of the population and is driven by type-2 inflammation, epithelial barrier dysfunction, and tight junction (TJ) disruption. Recent studies identify Zonulin and…
ISEF · 2026
Translational Medical Science
Psoriasis silently torments 125 million people worldwide, yet current therapies such as corticosteroids and biologics thin the skin, suppress the immune system, and lose efficacy over time,…
CSEF · 2026
Medicine & Physiology (Senior Division) First Award
The glial scar that forms after ischemic injury creates a structurally and functionally complex barrier, yet how it regulates neural stem cell (NSC) fate remains unclear. Single-cell RNA seq…
CSEF · 2026
Medicine & Physiology (Junior Division) First Award
Antibiotic-resistant Pseudomonas aeruginosa is responsible for an estimated 559,000 deaths annually worldwide, and for immunocompromised patients like myself, it is a leading cause of mortal…
ISEF · 2026
Translational Medical Science Fourth Award
Anxiety is an ever-growing issue plaguing modern society as it becomes more prevalent in young adults and adolescents, particularly Generalized Anxiety Disorder (GAD). Despite the existence…
ISEF · 2026
Translational Medical Science
Lung cancer remains the leading cause of cancer-related mortality worldwide, and early detection significantly improves survival outcomes. Subsolid pulmonary nodules, including ground-glass…
ISEF · 2026
Translational Medical Science
Headache disorders are among the top three most common neurological conditions, affecting 40% of the global population, yet 50–80% of migraine patients are misdiagnosed due to fragmented dia…
ISEF · 2026
Biomedical and Health Sciences
The gut and adipose tissue work in concert to modulate metabolic health and the immune system by producing short-chain fatty acids (SCFAs). FFAR2 signaling plays a vital role in regulating m…
CWSF · 2026
Disease & Illness Silver Medal
One-third of individuals with schizophrenia are treatment-resistant, largely because the disorder’s biological mechanisms are poorly understood, and as a result, current treatments fail to a…