Browse real student projects, abstracts, and awards.
ISEF · 2019
Biomedical and Health Sciences
Clostridium difficile is an anaerobic gram positive gastrointestinal bacterium. Existing treatments for C. difficile, such as antibiotics, have not proven to be highly effective because of t…
ISEF · 2019
Biomedical and Health Sciences
Chemotherapy is an effective, yet destructive way to treat most cancers. Mucositis, characterized by the ulceration of mucosal membranes, is a common negative side-effect of gastrointestinal…
ISEF · 2019
Biomedical and Health Sciences
Purpose Hemophilia A (FVIII deficiency) is characterized by spontaneous bleeding in weight-bearing joints, resulting in an orthopedic complication called hemophilic arthropathy (HA). Bleedin…
ISEF · 2019
Translational Medical Science
This project was conducted to find more information on Identifying and Drug Susceptibility of Gram-Negative Bacteria Found In Bactrocera Xanthodes (Pacific Fruit Fly). The purpose of this pr…
ISEF · 2019
Biomedical and Health Sciences Fourth Award
Insulin is a hormone produced by the pancreatic beta cells in the human body. Individuals with diabetes either lack insulin (T1D) or have a reduced insulin secretion (T2D). Therefore, the pr…
ISEF · 2019
Biomedical and Health Sciences
Gene fusions are chromosomal aberrations thought to have oncogenic functions, causing nearly 20% of global cancer morbidity rates. This investigation focused on YAP1 fusions. YAP1 (yes assoc…
ISEF · 2019
Biomedical and Health Sciences
Multiple myeloma (MM), a plasma cell malignancy, remains incurable despite the development of new therapies. MM is the second most frequent hematological malignancy in the United States. Cur…
ISEF · 2019
Biomedical and Health Sciences Third Award
Glaucoma is a neurodegenerative eye disease affecting more than 64.3 million people worldwide. The retinal degeneration is, as believed, originally caused by elevated intraocular pressure. N…
ISEF · 2019
Translational Medical Science
Cholangiocarcinoma originates in the biliary tract and is usually diagnosed at advanced stages and has a high resistance to chemotherapy. The 5-year relative survival rate is about 10% for p…
ISEF · 2019
Translational Medical Science
The Chaga mushroom (Inonotus obliquus) is a parasitic fungus. Commonly referred to as “black gold,” the charcoal colored mushroom grows mostly on birch trees in very cold areas around the wo…
ISEF · 2019
Translational Medical Science
In the United States we are currently facing a serious opioid drug abuse epidemic. According to research, 5,455 people (ages 15-24) died of drugs in 2017. Although these opioids are strictly…
ISEF · 2019
Translational Medical Science
The researcher conducting this experiment investigated the role of the Cat-2 gene in developing substance dependence. Substance dependence/addiction is an emerging public health crisis with…
ISEF · 2019
Translational Medical Science
More than a million people die annually due to exsanguination following trauma. The aim of this project is to shorten the platelet activation time. It was hypothesized that a wound dressing…
ISEF · 2019
Biomedical and Health Sciences
This research investigated the effects of polychlorinated biphenyls (PCB) on rat ovaries and determined the extent to which the aryl hydrocarbon receptor (AhR) mediated the adverse effects o…
ISEF · 2019
Translational Medical Science Third Award
Amblyopia is the most frequent vision disorder in children leading to permanent visual impairment. Prevalence of amblyopia varies from 1.1%-5% in various studies. Early detection through a c…
ISEF · 2019
Biomedical and Health Sciences
A recent rise in the use of opioids during pregnancy in the United States has resulted in an increase in neonatal abstinence syndrome (NAS). The effects of opioid use during pregnancy on new…
ISEF · 2019
Biomedical and Health Sciences
Purpose: Acute Myocardial Infarction (AMI) affects > 1 million people, kills ~ 400,000/year and costs > 300 Billion dollars. Some patients with AMI die from various causes, one of which is E…
ISEF · 2019
Biomedical and Health Sciences
Idiopathic Pulmonary Fibrosis (IPF) is a lung disease that results in scarring (fibrosis) of the lungs with no known cause. Over time, the scarring becomes so severe that breathing becomes i…
ISEF · 2019
Biomedical and Health Sciences
We developed a calorimetrical method for calculating the energetical value of the pre-made food. We propounded the results to the restaurants in Tbilisi and other regions of Georgia and sugg…
ISEF · 2019
Biomedical and Health Sciences
Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant cancers worldwide. However, the current treatments fail to control its progression. PDAC cells utilize glutamine as the m…
ISEF · 2019
Biomedical and Health Sciences
Galactic Cosmic Rays are primarily composed of protons (85%), helium (14%), and (~1%) high charge-high energy ions (HZE) such as 56Fe, 28Si, and 16O. Humans are normally not exposed to HZE i…
ISEF · 2019
Biomedical and Health Sciences
Gold nanoparticles, gold nanorods (GNRs) more specifically, are being studied for their innovative applications in imaging, targeting, therapeutics, and potential for a revolution in medical…
ISEF · 2019
Biomedical and Health Sciences
Brachytherapy is a cancer treatment procedure that implants applicators, often catheters and needles, for the delivery of a sealed radiation dose. While brachytherapy enables precise targeti…
ISEF · 2019
Biomedical and Health Sciences
This study examined the effects of a treatment protocol for Alzheimer’s Disease (AD) consisting of near infrared light (NIR) and C. longa. Mutated D. melanogaster, engineered to express the…
ISEF · 2019
Biomedical and Health Sciences Fourth Award
Negative-pressure-wound-therapy (NPWT), a wound-closure technique used following tumor resection has been suggested to promote metastasis. As this claim isn’t well established and the molecu…
ISEF · 2019
Translational Medical Science
Cancer is one of the leading causes of death every year throughout the world, lung cancer and breast cancer are the most prevalent. The purpose of the project Neural Networks and Cancer is t…
ISEF · 2019
Biomedical and Health Sciences
With an ~70% fatality rate, ovarian cancer is classified as the deadliest gynecological malignancy. Recent gene therapy using p53 failed. An alternative approach to wild type (wt) p53 is mit…
ISEF · 2019
Translational Medical Science
The prolonged exposure to UV rays emitted by the sun, has generated various diseases that affect human health, such as: skin burns, premature photoaging and it can worsen skin cancer. These…
ISEF · 2019
Biomedical and Health Sciences
Increased telomerase activity and sustained telomeres are hallmarks of non-small cell lung cancer (NSCLC) and encourage cancer growth by inhibiting cellular apoptosis. This study analyzes Pi…
ISEF · 2019
Biomedical and Health Sciences Third Award
Hypodiploid B-cell acute lymphoblastic leukemia (B-ALL) is a high-risk form of acute leukemia with a dismal prognosis. Because standard chemotherapy is largely ineffective for this subtype,…