20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2026
Biomedical and Health Sciences
Over 400 million people lack access to basic healthcare globally, with physician-to-patient ratios below 1 per 10,000 in low-resource regions. Language barriers, limited diagnostic infrastru…
CWSF · 2026
Disease & Illness Bronze Medal
Over 220,000 people live with ALS globally today, a number projected to rise 69% by 2040. Yet diagnosis still takes an average of 12 months after symptoms appear, no effective treatment is w…
ISEF · 2026
Translational Medical Science
Esophageal obstruction caused by cancer and benign strictures can severely impair swallowing, leading to poor nutrition and reduced quality of life. Although conventional stents are commonly…
ISEF · 2026
Translational Medical Science
Age-related macular degeneration (AMD) is a neurodegenerative eye disease that impacts roughly 200 million people worldwide. It occurs in the macula, which contains a dense number of photore…
CWSF · 2026
Health & Wellness
How does social media affect self-esteem in different age groups? We chose to study the relationship between social media and self-esteem in various age groups and many different relationshi…
CWSF · 2026
Disease & Illness
Marfan syndrome (MFS), a connective tissue disorder caused by FBN1 gene mutations, affects 1 in 5000 individuals. Current interventions for MFS are insufficient; they only mitigate symptoms…
CWSF · 2026
Health & Wellness Silver Medal
A Technical Method of Responsive Cellophane Films for Real Time Spoilage Detection is a scientific innovation experiment that identifies and tests a cellophane film fabricated with red cabba…
CWSF · 2026
Health & Wellness
In this project I tried to find new and simple ways to produce clean water anywhere in my community, or out on the land. Access to clean water for drinking and household use in my community…
CWSF · 2026
Health & Wellness Gold Medal
This project explores how a wearable tail could help seniors with Parkinson’s disease maintain balance, reducing their risk of falls. Using built-in sensors to detect when they are unstable,…
ISEF · 2026
Biomedical and Health Sciences
Cancer progression is driven by immune tolerance, insufficient co-stimulation, and impaired danger signaling within the tumor microenvironment, limiting anti-tumor immunity. This study prese…
CWSF · 2026
Health & Wellness Silver Medal
Oral diseases affect nearly 3.7 billion people worldwide, making them one of the planet’s most widespread and neglected health burdens. Although largely preventable, these conditions often p…
CWSF · 2026
Health & Wellness Bronze Medal
Have you ever wondered if certain sounds could affect memory or efficiency in studying? This project, tested how the two highest binaural beats-Beta and Gamma- would affect student's short t…
CWSF · 2026
Disease & Illness
Alzheimer’s disease is typically treated after symptoms appear, despite evidence that underlying changes begin years earlier. I investigated whether early calcium dysregulation and disrupted…
ISEF · 2026
Translational Medical Science
EquiliMind is a multimodal fall-prevention system designed to address the unpredictable vertigo, imbalance, and sudden fall risk associated with Ménière’s disease. Current clinical approache…
ISEF · 2026
Translational Medical Science
Alzheimer's disease disproportionately affects Latinx communities, yet most prediction models rely on neuroimaging biomarkers that are costly and inaccessible to underserved populations. Thi…
ISEF · 2026
Biomedical and Health Sciences
Overexpression of BCL-2 and XIAP proteins inhibits caspase-mediated apoptosis in mutated cells, promoting survival and driving chemoresistance, leading to poor clinical prognosis, highlights…
ISEF · 2026
Translational Medical Science
Breast cancer, the most common cancer in women, is treated with chemotherapy drugs, a systemic treatment prone to multidrug and chemoresistance. An improved adjunctive treatment that increas…
ISEF · 2026
Translational Medical Science
The lack of rapid, accessible, and precise quantitative biomarkers for lesion grading remains the primary barrier to preventing cervical cancer—a leading cause of cancer death among women wo…
ISEF · 2026
Translational Medical Science
It is estimated that approximately 9.8% of the world's population suffers from acne, a dermatological condition that can have significant clinical and psychosocial impacts, compromising the…
ISEF · 2026
Biomedical and Health Sciences
Uncontrolled minor bleeding requires effective, safe, and accessible materials. However, most commercial hemostatic dressings rely on synthetic, non-renewable polymers and present high produ…
CWSF · 2026
Disease & Illness Bronze Medal
Glioblastoma (GBM) is the most common primary brain tumor (Mayo Clinic, 2025), presenting with a 5-year survival rate of 5-10%. Current treatments for GBM are impeded by the tumor's aggressi…
ISEF · 2026
Biomedical and Health Sciences
Eosinophilic Esophagitis (EoE) is a chronic, immune-mediated esophageal disorder that currently requires repeated invasive endoscopic biopsies for diagnosis and disease monitoring. The absen…
CWSF · 2026
Health & Wellness Silver Medal
Your body tells the truth: 47% people underestimate their stress! Standard bots hallucinate and ignore physical limits. We fix this by syncing real-time body data with professional AI and im…
CWSF · 2026
Disease & Illness Bronze Medal
Diagnosing aggressive thyroid cancers like the tall-cell variant can be challenging because pathologists must determine whether the cancer cells are at least 3 times taller than they are wid…
ISEF · 2026
Translational Medical Science
Introduction: Parkinson’s disease (PD) is characterized by the loss of dopamine producing neurons. Many pathways involving mitochondrial dysfunction and synaptic function are involved in thi…
CWSF · 2026
Disease & Illness Gold Medal
My project focused on the embryonic development of the cerebellum. Little is known about how the cerebellum is formed during early embryonic development, and how its neural pathways are form…
CWSF · 2026
Disease & Illness
Our lungs are kept healthy by hair-like structures called cilia, found in our nasal passages, that act as brooms, sweeping bacteria out of our lungs. Primary Ciliary Dyskinesia (PCD) is a di…
ISEF · 2026
Translational Medical Science
Modern vaccines are effective but often depend on complex formulations containing depot-forming adjuvants and stabilizing excipients. Emerging approaches such as neoantigen cancer vaccines a…
ISEF · 2026
Biomedical and Health Sciences
Chronic cerebral hypoperfusion (CCH) seriously affects the well-being of the patient and has been proposed as a risk factor for cognitive impairment and dementia. While recent research has d…
ISEF · 2026
Translational Medical Science
Breast cancer progression is influenced by estrogen receptor signaling and tumor angiogenesis, yet the biological association between these pathways remains incompletely understood. The purp…