Browse real student projects, abstracts, and awards.
ISEF · 2026
Translational Medical Science
Neonatal brachial plexus injury (BPI) can lead to significant and lasting motor and sensory impairments, particularly because the brachial plexus is directly connected to the spinal cord. In…
ISEF · 2026
Translational Medical Science
Purpose. Osteosarcoma (OS) is an especially aggressive bone cancer disproportionately affecting children. Current treatments like surgery, chemotherapy, and radiation suffer from high recurr…
ISEF · 2026
Translational Medical Science
Alzheimer’s disease (AD) is projected to affect 150 million people by 2050 and is characterized by the accumulation of neurotoxic beta-amyloid (Aß) plaques in the brain, leading to severe me…
ISEF · 2026
Biomedical and Health Sciences
(This project was implemented in the city of Duhok, in the Kurdistan Region of Iraq, to solve the health problems caused by wastewater. It aims to treat the polluted water, recycle it, and m…
CWSF · 2026
Health & Wellness Silver Medal
500–800 years. That is how long a single disposable pad can remain in the environment. Despite being used by millions of people daily, most menstrual products are uncomfortable, environmenta…
ISEF · 2026
Biomedical and Health Sciences
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor dysfunction and neuron loss, with limited current treatments, revealing a critical gap. Heat shock…
CWSF · 2026
Health & Wellness
My project focused on how the Happy Days Mental Health app, which I built over a span of 3 years, affected the heart rate and calmed the body with all the activities involved on the app. I w…
ISEF · 2026
Biomedical and Health Sciences
While racial smoking disparities are well-documented, traditional socioeconomic models often overlook the discordance between educational attainment and income. This study investigates ‘stat…
ISEF · 2026
Biomedical and Health Sciences
Purpose: Antibiotic resistance is growing. Bacteriophages (phages) are viruses that infect bacteria; using phages and antibiotics together has a synergistic effect. This study applied phages…
ISEF · 2026
Biomedical and Health Sciences
In the US, 1 in 3 individuals develops cancer in their lifetime. Yet, drug failure rates remain near 90%. Deciphering immune-cancer interactions within the tumor microenvironment (TME) is im…
CWSF · 2026
Health & Wellness
Traditional vs Modern Medicines What will fight off the most bacteria, traditional or modern medicines. I used 3 traditional medicines and one modern medicine. I swabbed bacteria from my hoc…
CWSF · 2026
Disease & Illness Bronze Medal
Late stage cancers are often very hard to treat due to the tumor environment weakening the body's immune system, especially natural killer (NK) cells that normally destroy harmful cells. In…
ISEF · 2026
Translational Medical Science
Atypical Chemokine Receptor 1 (ACKR1/DARC) is a non-signaling chemokine receptor expressed on erythrocytes and endothelial cells. In tumors, ACKR1 modulates inflammation, chemokine gradients…
ISEF · 2026
Translational Medical Science
Retinal degenerative diseases (RDDs) affect 300 million patients worldwide. Current imaging techniques detect RDDs in late stages after significant vision loss. Approximately 40% of Retinal…
ISEF · 2026
Translational Medical Science
Melanoma is the most fatal type of skin cancer, taking over 50,000 lives annually. While advances in checkpoint immunotherapy have decreased mortality rates, it is difficult to determine whi…
CWSF · 2026
Disease & Illness
This project uses technology that allows our genetic code to be edited in order to create a new treatment plan for a genetic disorder called Tay-Sachs disease. This disorder has a 100% fatal…
CWSF · 2026
Health & Wellness
This experiment was created to test which types of UV light reduce the most amount of mold growth. It was hypothesized that if the mold was surrounded by UV-C light, the light with the short…
CWSF · 2026
Health & Wellness Gold Medal
Many patients are injured when IV fluids accidentally leak into their skin instead of staying in the vein. This causes painful swelling and bruising, and it happens to nearly 1 in 10 people.…
CWSF · 2026
Disease & Illness Bronze Medal
Speech and voice changes can serve as noninvasive indicators of disease, particularly in respiratory, neurological, and psychiatric conditions, where subtle changes in phonation, tone, or ar…
CWSF · 2026
Disease & Illness Gold Medal
Alzheimer's disease steals the memories of 55+ million worldwide, yet no effective diagnosis or treatment exists. The retina is composed of neural tissue, thus mirroring neurological damage…
ISEF · 2026
Translational Medical Science
Can neuron resilience be predicted as topological failure of cellular identity? Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease marked by TDP-43 aggregation and moto…
ISEF · 2026
Translational Medical Science
Dementia affects 55 million people globally, projected to reach 139 million by 2050. Although deep learning models achieve 90–98% accuracy for dementia classification, clinical adoption is h…
ISEF · 2025
Translational Medical Science
Neurodegenerative disorders like Alzheimer’s disease affect approximately 55 million people worldwide and are expected to double every 20 years. Standard detection methods, such as cerebrosp…
ISEF · 2025
Translational Medical Science
Sudden cardiac arrest (SCA) remains a significant health concern, accounting for over 436,000 deaths annually in the United States. An electrocardiogram (EKG) signal can help to identify ris…
ISEF · 2025
Translational Medical Science
In the last decade, the world has plunged into an opioid epidemic, with overdose deaths surging, amplified by the rise of synthetic drugs. In 2019, opioids accounted for 80% of global drug-r…
ISEF · 2025
Biomedical and Health Sciences
This project introduces a low-cost, portable diagnostic device for the rapid and accurate detection of pandemic-causing diseases. During the COVID-19 pandemic, millions of people lacked acce…
ISEF · 2025
Translational Medical Science
Coagulopathy defined as abnormal blood coagulation can cause thrombosis (hypercoagulation) or hemorrhage (hypocoagulation) leading to death. Current assays that provide a complete assessment…
ISEF · 2025
Biomedical and Health Sciences
In 2023, the Brazilian Amazon had the worst drought in history. People from the rural and indigenous areas suffered from many problems, especially hunger. In search of a food alternative fro…
ISEF · 2025
Translational Medical Science
Artificial Intelligence (AI) models like Convolutional Neural Networks (CNNs) are becoming powerful tools in medical imaging, but their “black box” nature limits clinical use. Doctors need t…
ISEF · 2025
Translational Medical Science
In recent years, research has demonstrated that the gut microbiome has an important role in normal brain function. This opens up possibilities for novel treatments of Alzheimer's, which affe…