Treating Late-Stage Tumor Immune Suppression: Multi-Modal TGFBR1 Drug Design

Overview

Late stage cancers are often very hard to treat due to the tumor environment weakening the body's immune system, especially natural killer (NK) cells that normally destroy harmful cells. In this project, I designed a potential drug that targets a crucial pathway which is responsible for this immune suppression. Using advanced computer modeling, I tested how well the drug binds to its target and whether it could work effectively within the body. I also evaluated its safety and ability to reach difficult areas like the brain. This innovative approach focuses on restoring the body's natural ability to fight cancer, rather than only trying to kill tumor cells directly. My work could help guide the development of more effective treatments for aggressive late stage cancers.

Awards (2)

• Bronze Medal
• Selected for CWSF 2026

Competition history

• CWSF 2026 Disease & Illness

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