38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2025
Biomedical and Health Sciences
Colorectal cancer (CRC) is the third most common cancer globally, with over 1.9 million new cases and nearly 1 million deaths annually. The incidence of early-onset CRC, defined as cancer oc…
ISEF · 2025
Biomedical and Health Sciences Fourth Award
Immune checkpoint inhibitors (ICIs) have emerged as a promising therapy for late-stage lung cancer. However, the response rate to ICIs remains low. As a result, there is a need to better und…
ISEF · 2025
Translational Medical Science
Metabolic disorders and malnutrition remain critical health concerns, often undiagnosed due to invasive, costly, and inaccessible testing methods. VitalEdge is a novel non-invasive biosensor…
ISEF · 2025
Translational Medical Science
Wound care management is a major medical challenge, causing significant clinical, social, and economic burden. To address this, I developed WoundView, an AI-powered app for real-time wound a…
ISEF · 2024
Translational Medical Science
Alzheimer's disease is a neurodegenerative disorder that affects more than 50 million people worldwide. Current diagnostic methods include cerebrospinal fluid testing, which is invasive and…
ISEF · 2024
Biomedical and Health Sciences
Mammography, currently the primary method implemented for breast cancer screening/detection, often produces false negatives (1 in 8). Additionally, there exist prolonged delays during diagno…
ISEF · 2024
Biomedical and Health Sciences
Accurately identifying the relationship between regulators and disease has long been a challenge in the field of biomedical research due to its crucial roles in pathobiological conditions. M…
ISEF · 2024
Translational Medical Science Second Award
Elderly populations are at an increasing risk of dementia, and accessibility to status-quo diagnosis tools is a significant issue, as proposed by the substantial rates of undiagnosed cases.…
ISEF · 2024
Translational Medical Science
Diabetic retinopathy (DR), a primary cause of vision loss worldwide, is projected to affect 130 million individuals by 2030. Difficulties related to diagnosis have led to an estimated underd…
ISEF · 2024
Translational Medical Science First Award
Renal Cell Carcinoma (RCC) is the world's deadliest urological disease. Although detection before metastasis can raise a patient's 5-year survival rate by over 75%, current diagnostic method…
ISEF · 2024
Translational Medical Science Fourth Award
Wound care is an essential part of patient healthcare. However, infections worldwide are increasing at a record rate due to disease, microbes, and antibiotic resistance. Unfortunately, preve…
ISEF · 2024
Translational Medical Science
Diabetic retinopathy (DR), a prevalent complication of diabetes, poses a significant threat to vision health, particularly in resource-limited rural settings. In 2023, a regional study in Al…
ISEF · 2024
Translational Medical Science Fourth Award
Arsenic is toxic. The primary goal of this research is to scientifically detect and quantify arsenic levels in drinking water due to local residents’ concerns and assess the potential health…
ISEF · 2024
Translational Medical Science Third Award
Microglial cells have the ability to engulf HIV-1 infected glial cells by binding to neuronal blebs, effectively stopping the subsequent encephalopathy. However, two HIV-1 accessory proteins…
ISEF · 2024
Translational Medical Science Third Award
The precise and accurate leukemia detection in current clinical practice remains challenging due to limitations in cost, time, and medical experience. To address this issue, this research de…
ISEF · 2024
Translational Medical Science
Ocular melanoma is one of the rarer types of aggressive cancer. The only option for someone with this cancer is to undergo radiation or surgery. In both cases, there is a high likelihood of…
ISEF · 2024
Translational Medical Science
Alzheimer's Disease is one of the leading causes of death of adults in the USA. The primary hallmarks of Alzheimer's are Amyloid-Beta plaques and Tau-Aggregation, known for causing inflammat…
ISEF · 2024
Biomedical and Health Sciences
Polycystic Ovary Syndrome (PCOS) is an endocrine disorder characterized by hormonal imbalance due to excessive levels of androgens and affects approximately 10% of women. Caenorhabditis eleg…
ISEF · 2024
Translational Medical Science
The objective of this study was to investigate the effect of Metformin, the effect of Y15, and the combinational effect of Y15 and Metformin for the treatment of platinum-resistant ovarian c…
ISEF · 2024
Biomedical and Health Sciences Third Award
The prediction and optimization of drug solubility in various formulations play a pivotal role in drug development. Statins (STN), a widely prescribed cholesterol-lowering drug family, exhib…
ISEF · 2024
Translational Medical Science Fourth Award
I propose a method that enables the development of treatments for the 350 million people worldwide suffering from 7,000 rare genetic diseases. Genomic therapies for rare genetic diseases are…
ISEF · 2024
Biomedical and Health Sciences Fourth Award
Neuroinflammation in the hippocampus and hypothalamus constitutes the common pathology underlying various neurodegenerative diseases and metabolic syndrome, respectively. Environmental induc…
ISEF · 2024
Translational Medical Science Fourth Award
Neurofibromatosis 1 (NF1) is an autosomal dominant cancer predisposition syndrome that affects 1 in 3,000 individuals indiscriminately. It is primarily characterized by the growth of periphe…
ISEF · 2024
Biomedical and Health Sciences
For the past three years, I have been conducting research and experiments on several different antibiotic ointments and their effectiveness against different bacteria. This year, Neosporin a…
ISEF · 2024
Biomedical and Health Sciences
For decades, lung cancer has been the leading cause of cancerous deaths worldwide. Much of lung cancer's lethality is attributed to its high incidence of tumor relapse and drug resistance. I…
ISEF · 2024
Biomedical and Health Sciences
Lung cancer ranks as the third leading cause of deaths in the Philippines and a major global contributor to cancer-related mortality. It is recognized that several natural products have anti…
ISEF · 2024
Translational Medical Science
Resistance to antimalarial drugs has increased the mortality rate in malaria cases globally. Artemisinin-based Combination Therapies (ACTs) are the first-line malaria treatment worldwide by…
ISEF · 2024
Translational Medical Science
Bladder cancer is the fourth most common cancer among men, affecting more than 80,000 people in the United States every year. Cisplatin, a chemotherapy agent, is employed in the standard-of-…
ISEF · 2024
Biomedical and Health Sciences
Stroke is a severe neurological disease that affects many people around the world. Post-stroke dysphagia complications can lead to malnutrition, which further complicates the problem. Addres…
ISEF · 2024
Translational Medical Science
Based on data from the World Health Organization, in 2020, cancer accounted for 10 million deaths worldwide. Recent studies show promise in using specific metal nanoparticles to selectively…