38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
AJAS · 2024
Biomedical and Health Sciences (inferred)
Osteosarcoma (OS) and rhabdomyosarcoma (RMS) are the most common malignant bone and soft-tissue sarcomas in children and adolescent young adults (AYA). Although the standard of care, which i…
AJAS · 2024
Biomedical and Health Sciences (inferred)
Alzheimer's Disease (AD) is a neurodegenerative disease that impacts more than 6 million Americans of all ages (Alzheimer's Association, 2023). The etiology of AD is the accumulation of amyl…
AJAS · 2024
Biomedical and Health Sciences (inferred)
Alzheimer’s disease (AD) and Parkinson's disease (PD), progressive neurodegenerative conditions, are characterized by neural apoptosis from amyloid beta and α-synuclein oligomeric proliferat…
AJAS · 2022
Medicine
In 2012, 5.1% of the burden of disease and injury worldwide was connected to alcohol consumption, which is why there is reason to believe that it is not just receptor inhibition that results…
AJAS · 2022
Medicine
Colorectal cancer cells express large amounts of PD-L2, a ligand of PD-1 that binds to PD-1 receptors on T-cells and sends “don’t eat me” signals to the T cells. Anti-PD-L2 monoclonal antibo…
AJAS · 2022
Medicine
Depression is a leading cause of death and disability with more than 264 million people of all ages suffering from the disorder worldwide. Understanding how brain function is altered in depr…
AJAS · 2022
Medicine
Ulcerative Colitis (UC) is a disease hallmarked by continuous inflammation along the gastrointestinal tract, which is largely the consequence of autoimmunity. Its prevalence continues to spr…
AJAS · 2022
Medicine
Cox Proportional Hazards Assumption Violations in Breast Cancer Gene Expression Data. Background: Cancer is a disease driven by mutations in genes that control cell proliferation, cellular d…
AJAS · 2022
Medicine
Recent advances show that the 14-3-3zeta protein is a unique regulator of IL-17A signal transduction. IL-17A signal transduction triggers two, 14-3-3zeta-TRAF5 and 14-3-3zeta-TRAF6-dependent…
AJAS · 2022
Medicine
The human gut harbors a dynamic population of microorganisms, including bacteria and viruses. The dominant gut microbial phyla are Firmicutes, Bacteroidetes, Actinobacteria, Proteobacteria,…
AJAS · 2022
Medicine
Glioblastoma is one of the most lethal cancers, associated with a bleak prognosis and no cure. Survival estimates given to patients are often inaccurate, as actual survival can range from mo…
AJAS · 2022
Medicine
Although the use of porous scaffolds in tissue engineering has been relatively successful, there are still many limitations that need to be addressed: low vascularization, low oxygen and nut…
AJAS · 2022
Medicine
Due to asthma, I took prednisone, an oral corticosteroid that reduces inflammation in the airways. During my 7th grade physical, my doctor noticed my growth rate had decreased from the 50th…
AJAS · 2022
Medicine
Electrocardiograms, or ECGs, are widely used technologies to record electrical signals from the heart to diagnose patients with various medical conditions. Currently, a shockingly high perce…
AJAS · 2022
Medicine
Investigations indicate that diabetic patients with myocardial infarctions (MI) have an increased risk of acute kidney injury (AKI) post-MI. In diabetic MI, blood hemoglobin (Hb) rises, whic…
AJAS · 2022
Medicine
To develop an alternative solution for Stress Urinary Incontinence (SUI) Stress urinary incontinence (SUI), is the leakage of urine by vigorous activities such as coughing and sneezing when…
AJAS · 2022
Medicine
The atrophic form of age-related macular degeneration (dry AMD) affects nearly 200 million people worldwide. There is no Food and Drug Administration (FDA)-approved therapy for this disease,…
AJAS · 2022
Medicine
Lung cancer is the leading cause of cancer-related deaths worldwide, with lung adenocarcinoma being the most common subtype. This study used statistical analysis to determine the prognostic…
AJAS · 2022
Medicine
The purpose of this experiment was to find out if deep learning models accurately diagnose patients with pneumonia. If deep learning models were used with Convolution Neural Network layers a…
AJAS · 2022
Medicine
Age-related Macular Degeneration (AMD) is the most common cause of vision loss in the United States, affecting over 10 million Americans. AMD impacts the retina, with an accumulation of unre…
AJAS · 2022
Medicine
Parkinson’s Disease (PD) is a progressive neurodegenerative disease that is characterized by loss of dopaminergic (DA) neurons of the substantia nigra, negatively affecting motor control and…
AJAS · 2022
Medicine
Systemic lupus erythematosus (SLE) is an autoimmune disease, which affects approximately 5 million people worldwide. Most SLE patients experience photosensitivity to ultraviolet (UV) rays fr…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Adult mesenchymal stem cells (MSC) have been cited to have immunoregulatory effects in addition to their regenerative and multipotency capabilities, meaning they contribute to a regenerative…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Obesity is associated with chronic inflammation of the adipose tissue. This inflammation aggravates the current state of obesity, making it harder to treat, and leads to life-threatening sid…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Permanent hearing loss due to the unsafe use of personal listening devices (PLDs), such as earbuds and headphones, has become increasingly common. The purpose of this experiment was to disco…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Glioblastoma is the most common primary brain tumor in adults. Patients have a poor outcome with a median survival time of 12 months; the disease is always fatal. Long non-coding RNAs have b…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Glioblastomas (GBM) are the most common primary malignant brain tumor in adults and are recognized as one of the deadliest forms of cancer. Despite aggressive therapy consisting of maximal s…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Tumor mediated immunosuppression allows tumors to hide from the immune system and avoid recognition. One way of reversing this suppressive microenvironment is to activate antigen-presenting…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Major depressive disorder (MDD) is a common mental disorder that affects adolescents and adults, causing staggering economic burdens, disabilities in the workforce, and suicidal thoughts, if…
AJAS · 2020
Biomedical and Health Sciences (inferred)
Potential roles for DGB25 adipose thermogenesis Jack Volpert1, Daniel Kramer2, Paul Cohen2 1 Riverdale Country School Bronx, NY 2Laboratory of Molecular Metabolism, Rockefeller University, N…