11705 projects whose affiliated fair was here, most recently in 2026.
ISEF records a state or province for some finalists and not others, so these counts do not add up to the country total.
11705 projects · showing 1591–1620
ISEF · 2025
Cellular and Molecular Biology
Alzheimer's disease (AD) pathogenesis follows a pattern of selective vulnerability, defined by varying levels of neurodegeneration across brain regions and neuronal populations. While the me…
ISEF · 2025
Plant Sciences
This research studies the effects of three different water types: purified, tap, and lake water on the regrowth of store-bought lettuce stems. Its objective is to identify how water quality,…
ISEF · 2025
Biochemistry
Hyperactive Wnt signalling causes over 90% of colorectal and 50% of breast cancers. It is driven by excessive nuclear translocation of mutant ß-catenin (ArmS10 in Drosophila), yet the exact…
ISEF · 2025
Energy: Sustainable Materials and Design
Air batteries are an emerging technology for renewable energy storage. Their distinct chemical properties convert atmospheric oxygen into viable electric energy. Currently, air batteries are…
ISEF · 2025
Mathematics
This project investigates the representation of polygons through the roots of unity. Since the points in the complex graph of power functions lead to equidistant solutions, they can then be…
ISEF · 2025
Plant Sciences
Marine microalgae are responsible for nearly 50% of their ecosystem's oxygen production and primary productivity, making them essential in the marine environment. These organisms also play a…
ISEF · 2025
Biomedical Engineering
Diabetes is one of the leading causes of death and chronic disease in the United States. Current glucose monitoring devices require painful blood sticks that lead to poor monitoring adherenc…
ISEF · 2025
Engineering Technology: Statics & Dynamics
The aerospike rocket engine, developed in the late 1960s, was designed to address a significant limitation of traditional bell rocket engines: inefficient exhaust gas expansion across varyin…
ISEF · 2025
Physics and Astronomy
Shear-thickening fluids (STFs) were added to Kevlar to find their effect on force absorbed by material over a short period of time. This could be used in spacesuits to protect against microm…
ISEF · 2025
Biomedical Engineering
The current healthcare workforce shortage requires us to reevaluate our approach to training future healthcare professionals. This study assesses a virtual reality application with gamificat…
ISEF · 2025
Physics and Astronomy
After reading that exposure to high-frequency radio waves could have adverse effects on humans and the environment, my interest was piqued in the possibility of minimizing exposure to this n…
ISEF · 2025
Cellular and Molecular Biology
Finding a treatment for breast cancer has been a persisting need as one in eight women will experience this disease in her lifetime. Current treatment options present harmful side effects an…
ISEF · 2025
Computational Biology and Bioinformatics
The m6a methylation of the TAR region promotes neuroinflammation in HIV-1 neurocognitive disorders. This is facilitated by the RBM15 protein recognizing and binding U-rich bulges to act as a…
ISEF · 2025
Physics and Astronomy
In the aftermath of tragedies like the Surfside Condo Collapse of 2021, the necessity for long-term monitoring methods to detect structural deterioration has significantly increased. Mechani…
ISEF · 2025
Biomedical and Health Sciences
Cardiac complications associated with SARS-CoV-2 infection include arrhythmias, myocarditis, and heart failure. However, the pathogenesis underlying COVID-19-induced cardiac dysfunction rema…
ISEF · 2025
Biomedical and Health Sciences
COVID-19, caused by SARS-CoV-2, has been associated with a range of cardiovascular complications, including arrhythmias and cardiomyopathy. This study investigates how the SARS-CoV-2 spike p…
ISEF · 2025
Translational Medical Science
Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder affecting millions of women worldwide. It is characterized by irregular periods, alopecia, hyperandrogenism, infertility, hirsutis…
ISEF · 2025
Behavioral and Social Sciences
Olfaction or the sense of smell plays a fundamental role in the animal kingdom's survival and may serve a marker for human disease, including mental disorders. This study’s objectives are: 1…
ISEF · 2025
Environmental Engineering
The NOAA defines microplastics as "plastic pieces less than five millimeters long." Microplastics have been found from the Mariana Trench to Mount Everest, and from the human brain to the pl…
ISEF · 2025
Systems Software
As cyber-attacks become increasingly common (72% increase from 2021), and as losses from cybercrime grow each year ($10.5 trillion by 2025), it is more important than ever for organizations…
ISEF · 2025
Engineering Technology: Statics & Dynamics
The Rio Grande Gorge bridge has an average of six suicides/year, as compared to 13.6 suicides/year (Atkins-Witmer, Woods, 2013) for the Golden Gate bridge. Per capita, this is a comparable s…
ISEF · 2025
Engineering Technology: Statics & Dynamics
Each time a rocket is launched into the Earth's atmosphere it uses several thousands of gallons of chemical fuel per second. These chemical fuels, when being used in such large quantities, c…
ISEF · 2025
Materials Science
With more than 360 million tons of plastic produced each year, plastic pollution has become a critical issue as plastics accumulate in our environment and inside us; microplastics are even k…
ISEF · 2025
Microbiology
Quorum Sensing (QS) is a bacterial communication pathway that mediates population-based activity activities such as virulence, motility, conjugation, and biofilm formation. Specifically, QS-…
ISEF · 2025
Chemistry
More than half the world's population, around 4.4 billion people, lack access to clean and safe drinking water. This is partially due to the contamination of synthetic organic dyes, which ar…
ISEF · 2025
Cellular and Molecular Biology
The purpose of this experiment was to design a cell model using a rat pheochromocytoma (PC12) cell to simulate Diabetic Peripheral Neuropathy (DPN). It was proposed that the higher the level…
ISEF · 2025
Biomedical and Health Sciences
Triple-negative breast cancer (TNBC) is a subtype of breast cancer which has none of the known unique biomarkers of the other subtypes. There is no established targeted treatment for TNBC an…
ISEF · 2025
Biomedical Engineering
CRISPR-Cas9 has emerged as a catalyst in treating genetic diseases such as sickle cell disease and transfusion-dependent beta thalassemia. Multiplex CRISPR-Cas9 is a subsystem of CRISPR edit…
ISEF · 2025
Engineering Technology: Statics & Dynamics
Learning to skateboard is challenging and often leads to injury. Unlike bikes, skateboards do not have a universal training aid for beginners. This project aimed to create a device similar t…
ISEF · 2025
Engineering Technology: Statics & Dynamics
This project presents an innovative Thrust-Vectoring Unmanned Aerial Vehicle (UAV) specifically designed to perform contact-based inspections(ultrasonic crack detection, wave check, and adhe…