11705 projects whose affiliated fair was here, most recently in 2026.
ISEF records a state or province for some finalists and not others, so these counts do not add up to the country total.
11705 projects · showing 391–420
ISEF · 2026
Computational Biology and Bioinformatics
Glioblastoma Multiforme is the most common aggressive brain tumor and is difficult to treat due to its invasive growth, tumor heterogeneity, and blood-brain barrier. EZH2, an epigenetic regu…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Heating and cooling systems account for nearly 50% of the global energy consumption. Heat exchangers are critical components of all heating and cooling systems. Heat transfer efficiency is a…
ISEF · 2026
Animal Sciences
The purpose of the experiment was to see if FerAppease had an effect on calves during times of stress. The procedure for this experiment is as follows: Once calves are separated from mother,…
ISEF · 2026
Environmental Engineering
Microplastics (MPs), defined as plastic particles smaller than 5 mm, are pervasive environmental pollutants linked to cardiovascular, neurological, and carcinogenic health risks. Although fe…
ISEF · 2026
Mathematics
Benzenoids are organic compounds composed of hexagonal six-carbon benzene rings with no adjacent double bonds. A Kekulé structure models a benzenoid as a collection of selected edges (repres…
ISEF · 2026
Biochemistry
Three platinum anticancer compounds have been used for over 40 years in the United States. Despite their longtime use, it wasn't until 2017 that it was discovered that one of the platinum dr…
ISEF · 2026
Earth and Environmental Sciences
Wildfire response depends on three tasks that currently operate in isolation: detecting fires, forecasting where they will spread, and deciding where to send crews. Existing detection relies…
ISEF · 2026
Physics and Astronomy
Arterial stenosis, the narrowing of arteries by plaque buildup, is the primary cause of cardiovascular diseases. Diseased arteries often contain multiple or non-uniform stenoses, so clinical…
ISEF · 2026
Earth and Environmental Sciences
The South Pacific Convergence Zone (SPCZ) is the largest band of precipitation in the Southern Hemisphere stretching from the Western Pacific Warm Pool (WPWP) to French Polynesia. The WPWP c…
ISEF · 2026
Biomedical and Health Sciences
Lactase dietary supplements are widely used to address lactose intolerance, a condition where the small intestine produces insufficient lactase enzyme to break down lactose, the natural suga…
ISEF · 2026
Mathematics
An infinite iterated function system (IFS) associated with local inverse branches of the Riemann xi-function near its simple zeros is constructed. Throughout, all zeros of the xi-function ar…
ISEF · 2026
Mathematics
Vigneras (1979) proved the existence and recursive properties of the Multi Gamma Hierarchy, as well as a general version of the Bohr-Mollerup theorem for discrete cases. In this project, we…
ISEF · 2026
Behavioral and Social Sciences
Mental health disorders affect approximately 23% of American adults, highlighting the need for improved diagnostic tools (NIMH, 2024). Current diagnoses rely on self-reported surveys and cli…
ISEF · 2026
Computational Biology and Bioinformatics
Parkinson's disease (PD) affects over 10 million people globally. It is driven by the intrinsically disordered (IDP) protein a-synuclein (asyn). While asyn's flexibility is functional, it en…
ISEF · 2026
Behavioral and Social Sciences
Many teachers have started using phones as a way to encourage students in the classroom. I wondered how effective this method was, and what some of the undesirable consequences could be. The…
ISEF · 2026
Software Design
As hyper-realistic deepfakes grow into one of the world’s most pressing crises, the rush to secure digital integrity has made watermarking one of the most urgently researched sectors in cybe…
ISEF · 2026
Translational Medical Science
Triple-negative breast cancer (TNBC) remains a clinical challenge due to its aggressive nature and the lack of targeted therapies. Traf2 and NCK-interacting kinase (TNIK), a key regulator of…
ISEF · 2026
Biomedical and Health Sciences
Human Immunodeficiency Virus (HIV) infection is associated with neurocognitive dysfunction (NeuroHIV), which can occur in 30–50% of people with HIV, despite successful combination antiretrov…
ISEF · 2026
Earth and Environmental Sciences
Polyethylene glycol (PEG) is a synthetic polymer commonly found in cosmetic products such as shampoos and conditioners. Its widespread use raises environmental concerns due to its accumulati…
ISEF · 2026
Translational Medical Science
Meniscus injuries are among the most common orthopedic conditions, with approximately 1 million surgeries annually. Injuries in the avascular zone cannot self-regenerate, and modern scaffold…
ISEF · 2026
Engineering Technology: Statics & Dynamics
This project built upon last year’s research (2024-2025), testing the relationship between the final current (Cf) and the final temperature (Tf) of a cotton candy machine modified for plasti…
ISEF · 2026
Computational Biology and Bioinformatics
Worldwide, breast cancer kills 700,000 women annually. Although 5 years of tamoxifen (Tam) therapy cuts the risk of progression in half, 40% of patients develop resistance (TamR), driven by…
ISEF · 2026
Materials Science
The annual generation of 3.8 million tons of shrimp shell waste contributes to environmental toxicity, and microplastics from conventional plastics cause adverse health impacts. To combat th…
ISEF · 2026
Environmental Engineering
Widespread contamination of surface and groundwater systems from heavy metals, excess nutrients, and other hazardous pollutants has intensified the need for sustainable water remediation tec…
ISEF · 2026
Computational Biology and Bioinformatics
Systemic inflammatory diseases like cirrhosis, ankylosing spondylitis (AS), and hypertension affect over 1 billion people and are often detected after significant organ damage. Growing evide…
ISEF · 2026
Biomedical and Health Sciences
Parkinson's disease is a progressive neurodegenerative disorder requiring early intervention, yet screening is often delayed due to a dependency on expensive, in-person clinical assessments.…
ISEF · 2026
Cellular and Molecular Biology
Alzheimer's disease is a neurodegenerative disorder characterized by loss of matter in the brain driven by amyloid-ß (Aß) aggregation. In scientific literature, the role of inhibitory neurot…
ISEF · 2026
Technology Enhances the Arts
This project determined if playing different games in different amounts would affect typing speed and accuracy. The experiment was performed due to personal research that showed an increase…
ISEF · 2026
Biochemistry
Breast cancer remains the most prevalent malignancy among women worldwide. Dose-dense AC-T chemotherapy (Adriamycin, Cyclophosphamide, and Paclitaxel), a commonly prescribed regimen, is asso…
ISEF · 2026
Environmental Engineering
Polyethylene terephthalate (PET) is one of the most common plastics used worldwide, and is used to create products like water bottles, food packaging, and textiles. PET is difficult to break…