20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2025
Systems Software
The purpose of this engineering design project is to create and optimize an AI-based tool that uses a patient's textual descriptions of symptoms to predict the potential severity of their co…
ISEF · 2025
Plant Sciences
Aquaponics is a process of producing food through a symbiotic relationship between fish, which provide nutrients, and plants, which purify water. This project assesses the effectiveness of n…
ISEF · 2025
Cellular and Molecular Biology
Metastatic prostate cancer (mPC) stands second in cancer-related mortality among men. As current treatment options are largely palliative, there is a dire need for novel therapeutic targets…
ISEF · 2025
Microbiology
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is once again the world's deadliest infectious disease, after being replaced by COVID-19 for three years. The only approved vaccine f…
ISEF · 2025
Microbiology
As artificial sweetener consumption rises, environmental contamination by sucralose has become a growing concern due to its persistence in aquatic ecosystems. Previous research has shown tha…
ISEF · 2025
Microbiology
The Cerrado, Brazil's second-largest biome, occupies 23% of the national territory and plays a crucial role in the agricultural economy, particularly in Mato Grosso do Sul, where pastures su…
ISEF · 2025
Translational Medical Science
Study Objective: The primary aim of this study was to investigate how P2X1 receptor activation in lung adenocarcinoma (LA) influences the tumor microenvironment, particularly in promoting pr…
ISEF · 2025
Physics and Astronomy
A transit occurs when an exoplanet blocks the light from its host star to cause a unique dimming. The Transiting Exoplanet Survey Satellite (TESS) is an all-sky scanning space telescope that…
CYSF · 2025
A study on how megafauna can be possible.
CYSF · 2025
This study explores treatment-resistant epilepsy, investigating the unique characteristics of the condition and exploring possible next steps in management or treatment options.
ISEF · 2025
Environmental Engineering
In 2022, global carbon dioxide emissions reached an estimated 36.8 billion metric tons, which has had a profound impact on climate change and environmental deterioration. The overall CO2 con…
ISEF · 2025
Environmental Engineering
The purpose of this project was to engineer a cyanobacteria mitigation device and test how deployed, regulated concentrations of hydrogen peroxide could kill cyanobacteria and how Great Mull…
ISEF · 2025
Biomedical and Health Sciences
Asymptomatic intracranial hemorrhage (aICH) patients present with either a decrease or no change in NIHSS scores, which may falsely indicate clinical improvement in the days leading up to th…
ISEF · 2025
Animal Sciences
Alzheimer’s disease (AD) is the 7th leading cause of death worldwide. It is characterized by the buildup of amyloid-ß plaques that trigger neuroinflammation and increase oxidative stress, ca…
ISEF · 2025
Systems Software
Alzheimer's disease presents a real challenge for caregivers, often leading to high stress and mental strain, as shown by Kim et al., 2021, Vu et al., 2022, and Hosseini, 2022. Informal care…
ISEF · 2025
Cellular and Molecular Biology
Translation initiation in human embryonic stem cells (hESCs) is governed by a delicate balance among canonical, cap-dependent and alternative pathways. This study dissects the roles of eIF4G…
ISEF · 2025
Mathematics
How likely is it that we are one of the luckiest among many evolutionary possibilities? The NK model, a mathematical exemplar describing Wright's fitness landscapes, has provided great insig…
ISEF · 2025
Chemistry
Global carbon dioxide (CO2) emissions, exceeding 37 billion tons annually, are intensifying environmental crises and threatening public safety. Electrochemical CO2 reduction reaction (eCO2RR…
ISEF · 2025
Computational Biology and Bioinformatics
Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by pervasive patterns of inattention, hyperactivity, and impulsivity that are inappropriate for…
ISEF · 2025
Translational Medical Science
Osteosarcoma (OS) is an aggressive bone cancer with poor survival rates due to chemoresistance. Chemotherapy, the main treatment, often fails as OS cells become resistant, leading to tumor g…
JSHS · 2025
Renaissance School of Medicine at Stony Brook University Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a 13% 5 -year relative survival rate. The limited number of…
ISEF · 2025
Translational Medical Science
One of the most common complications of chemotherapy treatment is febrile neutropenia (FN), affecting 50% of patients with a mortality rate as high as 21%. Oftentimes, fever is the first and…
ISEF · 2025
Systems Software
With the rise of Generative AI (Gen AI), academic dishonesty in the classroom has skyrocketed, with over 90% of students now admitting to using it for schoolwork. While Gen AI offers various…
ISEF · 2025
Systems Software
Efficient traffic navigation algorithms are vital for reducing congestion, emissions, and delays in modern cities. Yet, existing systems use “selfish” routing — optimizing individual travel…
ISEF · 2025
Robotics and Intelligent Machines
Coral reefs are vital marine ecosystems that face mounting environmental challenges, including climate change and pollution, which contribute to coral degradation and bleaching. This project…
CYSF · 2025
The aim of the project is to detect spoilage in prepackaged fruits by equipping reflectance-based imaging to develop a real-time spoilage detection system with AI-powered decision-making.
ISEF · 2025
Computational Biology and Bioinformatics
5-Fluorouracil (5-FU), a common chemotherapy for solid tumors, is metabolized primarily by dihydropyrimidine dehydrogenase (DPD), encoded by the DPYD gene. With > 200 known variants, individ…
ISEF · 2025
Computational Biology and Bioinformatics
Biologists often take sequential 2D images at different heights to study biological structures. Last year, one of us wrote software that creates a 3D rendering from these images. This year,…
ISEF · 2025
Robotics and Intelligent Machines
AutoMates presents a novel intelligent solution for multiple intelligent agents to self-learn performing complex, hard-to-optimize, and unpredictable tasks. It does this using a) a novel ite…
ISEF · 2025
Engineering Technology: Statics & Dynamics
A prevailing issue among the geriatric population is the difficulty of managing medication. With 36% of Americans over 65 using at least five prescription medications and 3% experiencing dem…