Browse real student projects, abstracts, and awards.
ISEF · 2025
Environmental Engineering
Since the invention of modern plastics during the 20th century, microplastics (MPs) have become one of the most pervasive anthropogenic pollutants on Earth—being found everywhere from the Ma…
ISEF · 2025
Biomedical and Health Sciences
Escherichia coli (E. coli) is one of the primary bacterial causes of urinary tract infections (UTIs), accounting for 75–95% of cases. Conventional antibiotics are commonly used for treatment…
ISEF · 2025
Energy: Sustainable Materials and Design
Low-temperature waste heat is an underutilized resource in industries, and energy-saving technologies can progress through the exploitation of this waste heat. In this study, we developed a…
ISEF · 2025
Materials Science
A Faraday cup is a conductive cup that serves as a plasma detector, catching the charged particles in a vacuum and measuring the particle flow rate. Due to its advantages in being simple, ac…
ISEF · 2025
Biochemistry
A rapid and simple method for detecting cortisol, a stress hormone, in saliva was developed for the early diagnosis of stress-related diseases. The detection was based on the reaction betwee…
ISEF · 2025
Systems Software
PDF-based stegomalware is a growing cybersecurity threat that disguises malicious payloads within the tree structure of PDF documents, exploiting features like embedded JavaScript, metadata,…
ISEF · 2025
Computational Biology and Bioinformatics
Tau protein aggregation is a hallmark of Alzheimer's disease (AD), disrupting neuronal function and impairing synaptic signaling. The clinical efficacy of tau aggregation inhibitors like TRx…
ISEF · 2025
Energy: Sustainable Materials and Design
Volcanic eruptions pose severe risks to human lives, infrastructure, and the environment, affecting 500 million people worldwide. Early warning can reduce fatalities by 60%, yet 80% of 1,500…
ISEF · 2025
Biomedical Engineering
The Flexshoe addresses foot and ankle swelling and circulation issues, especially common in the elderly, targeting conditions like pedal edema, chronic venous insufficiency, and diabetic ede…
ISEF · 2025
Robotics and Intelligent Machines
Waste pollution, driven by improper recycling practices, remains a pressing environmental issue that humans continually struggle to manage effectively. Building on last year's project, which…
ISEF · 2025
Physics and Astronomy
Turbulence is a natural phenomenon that serves as an underlying principle for many other fields, ranging from astrophysical studies of star formation to climate change modeling. Due to its c…
ISEF · 2025
Translational Medical Science
Major Depressive Disorder negatively affects millions worldwide by decreasing productivity, degrading physical well-being, and increasing the risk of suicide by 60%. Moreover, miscalculating…
ISEF · 2025
Embedded Systems
The Russia-Ukraine conflict has revealed that fiber-optic controlled UAVs can bypass conventional detection systems. Radar fails against low-altitude targets with small radar cross-sections;…
ISEF · 2025
Translational Medical Science
Cancer remains a leading cause of death worldwide, with approximately 10 million fatalities annually. Whole Slide Imaging (WSI) and Deep Learning can enhance histopathological analysis, enab…
ISEF · 2025
Earth and Environmental Sciences
Understanding pCO2 is essential for assessing the ocean's role in the global carbon cycle. However, in many current methods for predicting pCO2, satellite-derived measurements for regional w…
ISEF · 2025
Earth and Environmental Sciences
Water treatment plants use disinfectants like chlorine to eliminate waterborne diseases such as cholera and typhoid. However, disinfection results in the formation of disinfection byproducts…
ISEF · 2025
Computational Biology and Bioinformatics
T-cell malignancies contribute significantly to the high mortality rates of lung and colon cancers, two of the deadliest globally. Current CAR T-cell therapies, while promising, suffer from…
ISEF · 2025
Engineering Technology: Statics & Dynamics
The aerodynamic efficiency of an aircraft's nose cone is crucial to overall flight performance. Traditional nose cone designs are optimized for specific speed regimes, which limits their ove…
ISEF · 2025
Translational Medical Science
Alzheimer's disease (AD) remains difficult to diagnose in its early stages. Current diagnostic approaches often miss subtle early symptoms, delaying intervention. In this research, a novel m…
ISEF · 2025
Biomedical Engineering
Cancer spreads throughout the body in a process named metastasis. Circulating tumor cells (CTCs) play a critical role in promoting metastatic cancers, which cause approximately 90% of cancer…
ISEF · 2025
Robotics and Intelligent Machines
Due to growing industries and poor methods of recycling, landfills are filled with millions of tons of wasted recyclable materials. Making recycling more accessible to communities around the…
ISEF · 2025
Biochemistry
Antibiotic drug resistance causes an estimated 1 million deaths each year and over 200 trillion USD in healthcare costs. Amoxicillin (AMOX) is an antibiotic effective against a broad range o…
ISEF · 2025
Mathematics
In this study, I present a novel approach for model compression to reduce the size of neural network models. In recent years, with the rise of LLMs such as ChatGPT, deep learning models have…
ISEF · 2025
Biomedical and Health Sciences
Anthropogenic open burning is known to release hazardous chemicals and has been associated with an increased prevalence of cardiopulmonary issues. For example, studies show that veterans who…
ISEF · 2025
Embedded Systems
In recent years, radar technology has gained significant interest in its application in detecting vital signs. It has the potential to play a crucial role in identifying obstructive sleep ap…
ISEF · 2025
Systems Software
Fault tolerant quantum computing (FTQC) provides huge promises for industrial and scientific progress, such as in drug discovery and cryptography. Part of the technology stack required for F…
ISEF · 2025
Energy: Sustainable Materials and Design
Thirty-five million Americans have an implanted medical device (IMD), like a pacemaker. IMDs have a fixed battery life (~7-12 years), requiring invasive surgery to replace the battery, with…
ISEF · 2025
Earth and Environmental Sciences
Zooxanthellae is the mutualistic microorganism that lives in coral and provides nutrients for the expansion of coral with the byproducts of photosynthesis. The main photosynthetic pigment is…
ISEF · 2025
Microbiology
The oligodynamic effect is the ability of metals to kill microbes, including bacteria. This effect is vital to modern methods of sterilization, as biocidal metals are commonly incorporated i…
ISEF · 2025
Translational Medical Science
Hospital infection is a serious current problem, affecting patients and generating high costs for public healthcare. One solution would be sustainable and natural alternatives. In this way,…