JSHS · 2024
BLASTing Away Viruses!
The purpose of this experiment is to evaluate the effectiveness of vaccine predictions made by the WHO for Influenza outbreaks. This can be applied to real-world situations to enhance the ef…
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JSHS · 2024
Blood Biomarkers for Recognizing Mild and Moderate TBI
Today, there is no accurate way to diagnose Traumatic Brain Injury (TBI), especially when referring to mild or moderate injuries, and no way for medical professionals to guarantee presence a…
JSHS · 2024
Building a Neural Network: Predicting Mice Behaviors from rCPT Activity
Machine learning and artificial intelligence have truly become some of the most groundbreaking technologies of modern time. Particularly, in the field of behavioral neuroscience, deep learni…
JSHS · 2024
Caffeine’s Role in the Phytotoxicity of Spent Coffee Grounds
8 to 15 million tons of spent coffee grounds (SCG), the remainder left after brewing coffee grounds, is produced every year globally. To reduce waste in landfills, SCG has been proposed as a…
JSHS · 2024
California Southern EMBER: A Novel Quantum Computing Framework for Early Diagnosis and Predictive Biomarker Identification of Lung Cancer
Lung cancer is the most deadly form of cancer, responsible for over 2 million deaths annually. Its fatality is largely a result of difficulty in early detection, with survival rates dropping…
JSHS · 2024
Cell-Fie: A Machine Learning Tool to Improve the Accuracy of Fine -Needle Aspiration Biopsies in Diagnosing Breast Cancer
Breast cancer remains a leading cause of female mortality, claiming over 42,000 lives annually. Breast cancer is typically diagnosed using core -needle biopsies with very high accuracies; ho…
JSHS · 2024
Characterizing a Novel Flare in the Distant Quasar VIIIZw233
The universe is filled with turbulent events, from the collision of black holes to the death of a star in an explosive supernova. One such event is a Tidal Disruption Event (TDE), where a st…
JSHS · 2024
Chronic Sleep Deprivation Activates NLRP3 Inflammasome and Exacerbates Aβ Plaques Deposition in a Mouse Model of Alzheimer’s Disease
Chronic sleep deprivation (CSD) is a condition resulting from insufficient sleep over a prolonged period of time, which affects one in three adults in the United States. Alzheimer’s disease…
JSHS · 2024
Ciliatine-Induced Apoptosis in Colorectal Cancer Cells: Targeting PPARδ for Tumor Suppression
Colorectal cancer (CRC) is a leading cause of cancer-related deaths, and gut bacteria play a crucial role in its pathogenesis. Gut bacteria metabolize dietary substrates to produce various m…
JSHS · 2024
Circulating Chymase and Chronic Kidney Disease: An Analysis of Current Treatments, Demographics, and Clinical Risk Factors
Chronic kidney disease (CKD) results in a progressive loss of kidney function over time, affecting 37 million in the US. Chymase is the primary enzyme mediating angiotensin II formation inde…
JSHS · 2024
CisRF: A Novel Machine Learning Approach to Predict Context Dependent Impacts of Disease Associated Regulatory Elements on Gene Expression
Genome Wide Association Studies have identified 560,000+ Single Nucleotide Polymorphisms (SNPs) associated with disease, most of which are not in protein -coding regions of the genome. Howev…
JSHS · 2024
Classical and Modern Control Theory for Rotor Sail Active Seakeeping
90% of goods move by cargo ships, contributing to 3% of climate change emissions, 7.6 million childhood asthma cases, and 150,000 premature deaths annually. There is a need for climate chang…
JSHS · 2024
Comparative Study of Fruit Peel Biopolymer-based Composite Films
As single-use plastic pollution rises, bioplastic from renewable biopolymers offers a sustainable alternative; however, challenges persist in improving their mechanical properties. This stud…
JSHS · 2024
Comparing the Eddy Current Generation Between North -South Array and Halbach Array for Magnetic Induction Heating Element
This project aims to use an eddy current generator using a Halbach array to create a sustainable heating element for water desalination and test the effectiveness of a north-south array vers…
JSHS · 2024
Comparing the Success Rate for Acropora palmata (Elkhorn Coral) Outplanting between Local Volunteers and NOAA Marine Biologists in Puerto Rico
Elkhorn coral, Acropora palmata is a threatened species in the Caribbean. The degradation of the A. palmata population stimulated rehabilitation initiatives. This study analyzed the survivor…
JSHS · 2024
Crystallization and Morphology Tailoring via Functionalized Ligands for Efficient and Stable Perovskite Solar Cells
Perovskite solar cells have been regarded as one of the most promising alternatives to conventional polycrystalline silicon solar cells due to their excellent photovoltaic properties, flexib…
JSHS · 2024
Deep Learning Based Automated Platform for Sarcopenia Assessment and Outcomes Analysis in Head and Neck Cancer
Women’s Hospital The body composition status, which characterizes the levels of muscle and adipose tissue in a person’s body, is closely linked to cancer treatment risks and survival. Sarcop…
JSHS · 2024
Degradation of Residual Dyes from the Hydrolysis of PETE Plastic
Plastic pollution remains a problem, with over 170 trillion pieces of plastic in the world's oceans. A process that can efficiently degrade PETE plastic is hydrolysis, where the PETE is brok…
JSHS · 2024
De Novo Drug Design as GPT Language Modeling: Large Chemistry Models with Supervised and Reinforcement Learning
In recent years, generative machine learning algorithms have been successful in designing innovative drug- like molecules. SMILES is a sequence -like language used in most effective drug des…
JSHS · 2024
Depolymerization of PLA Plastics: A Novel Investigation of the Effect of Iron and Zinc Catalysts on Biodegradable Compounds
The use of biodegradable plastics is becoming more and more widespread, and this project’s aim is to depolymerize manufactured PLA products in order to obtain reusable polylactic acid. Zinc…
JSHS · 2024
Design And Construction of an Articulated Prosthetic Prototype Based on Fiberglass and Polylactic Acid for the Front Leg of a Canis Lupus familiaris
Mrs. Linda Correa, UPRP The demand for prostheses for animals is still low, mainly due to the cost involved. A prosthesis is a device designed to replace a body part. These devices can be us…
JSHS · 2024
Design and Evaluation of a Trap for Tracking the Settling Preferences of Adolescent Crabs
The purpose of this study was to design a trap that would be used to track whether or not crabs during their megalopa stage had a settlement preference. Knowing their settlement preferences…
JSHS · 2024
Design, Facile Synthesis, and Evaluation of a Chalcone-Based Small Molecule ULK1 Agonist for the Treatment of Huntington’s Disease
Huntington’s Disease (HD) is a fatal neurodegenerative disorder caused by a mutation in the huntingtin gene (HTT). This abnormal sequence codes for a mutated version of the huntingtin protei…
JSHS · 2024
Design of a Low-Cost, Low-Inertia, Backdrivable Humanoid Upper-body
General purpose humanoid robots have long been envisioned for a plethora of applications such as disaster relief, industrial automation, agriculture, or elderly assistance. A humanoid form f…
JSHS · 2024
Determining the Metamorphic Temperatures of Rocks in the Raspas Complex using Zirconium -in- Rutile Thermometry to Compare to Computer Models
The Raspas Complex in Ecuador, estimated to be approximately 120+ Ma old, is a metamorphic fossil subduction zone with diverse rock types including eclogites. This study determines the preci…
JSHS · 2024
Determining Whether the Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2) Gene Plays a Role in the Development of Type 1 Diabetes
Type 1 diabetes (T1D) is an autoimmune disease that leads to destruction of insulin producing 𝛽-cells. It is unknown what causes the disease and there’s no lasting cure. The protein tyrosine…
JSHS · 2024
DETICKT IT: A Machine Learning -Based Application for Real -Time Tick Identification and Spatiotemporal Disease Risk Assessment
There is an alarming increase in the population of ticks and tick-borne diseases (TBDs), with 475,000 cases reported annually, some of which are fatal (Kugeler et al., 2021). Due to limited…
JSHS · 2024
Developing a Python-based Synthetic Aperture Radar Visualization System for Flood Mapping
As we enter an era where natural disasters are increasing in frequency and intensity globally, the need for advanced disaster response technologies has never been more pressing. Floods, in p…
JSHS · 2024
Development and In Vitro Verification of a Polymersome for Blood-Brain Barrier Transport Through a Novel Machine Learning Model
Across neurological drug development, researchers struggle with the high selectivity of the blood -brain barrier (BBB), where most drugs are unable to pass from the blood into the brain. As…
JSHS · 2024
Development of Persistent DNA Vectors for Safe and Lasting Non-viral Gene Therapies
Scaffold/MatrixAttachment Regions (S/MARs) are specific regions of DNA that help to stabilize chromatin structure and regulate gene expression by facilitating interactions between DNA and th…