Browse real student projects, abstracts, and awards.
ISEF · 2025
Robotics and Intelligent Machines
Reliable and timely access to medical supplies is a significant challenge in regions with poor infrastructures and frequent natural disasters. Drones present a promising solution by enabling…
ISEF · 2025
Biomedical Engineering
Diabetes is one of the leading causes of death and chronic disease in the United States. Current glucose monitoring devices require painful blood sticks that lead to poor monitoring adherenc…
ISEF · 2025
Engineering Technology: Statics & Dynamics
The aerospike rocket engine, developed in the late 1960s, was designed to address a significant limitation of traditional bell rocket engines: inefficient exhaust gas expansion across varyin…
ISEF · 2025
Physics and Astronomy
Shear-thickening fluids (STFs) were added to Kevlar to find their effect on force absorbed by material over a short period of time. This could be used in spacesuits to protect against microm…
ISEF · 2025
Biomedical Engineering
The current healthcare workforce shortage requires us to reevaluate our approach to training future healthcare professionals. This study assesses a virtual reality application with gamificat…
ISEF · 2025
Physics and Astronomy
After reading that exposure to high-frequency radio waves could have adverse effects on humans and the environment, my interest was piqued in the possibility of minimizing exposure to this n…
ISEF · 2025
Biomedical Engineering
Atrial fibrillation (AF), the most prevalent heart arrhythmia affecting over 60 million people globally, is expected to double by 2050. As a leading contributor to 15-20% of all strokes, AF…
ISEF · 2025
Robotics and Intelligent Machines
Rip currents pose significant hazards to beach safety. They are unpredictable and strong, quickly pulling swimmers away from shore, often leading to drowning. To mitigate the harm of rip cur…
ISEF · 2025
Cellular and Molecular Biology
Finding a treatment for breast cancer has been a persisting need as one in eight women will experience this disease in her lifetime. Current treatment options present harmful side effects an…
ISEF · 2025
Computational Biology and Bioinformatics
The m6a methylation of the TAR region promotes neuroinflammation in HIV-1 neurocognitive disorders. This is facilitated by the RBM15 protein recognizing and binding U-rich bulges to act as a…
ISEF · 2025
Biochemistry
DNA replication is essential for the accurate transmission of genetic information during cell division. The Rothmund-Thomson syndrome helicase (RECQ4) plays a crucial role in replication ini…
ISEF · 2025
Animal Sciences
Bumblebees are social insects: one queen and many worker bees live in the nest. In the Japanese bumblebee Bombus ignitus, the queen lays fertilized diploid eggs that develop into female work…
ISEF · 2025
Physics and Astronomy
In the aftermath of tragedies like the Surfside Condo Collapse of 2021, the necessity for long-term monitoring methods to detect structural deterioration has significantly increased. Mechani…
ISEF · 2025
Biomedical and Health Sciences
Cardiac complications associated with SARS-CoV-2 infection include arrhythmias, myocarditis, and heart failure. However, the pathogenesis underlying COVID-19-induced cardiac dysfunction rema…
ISEF · 2025
Cellular and Molecular Biology
Manganese is a central promoter of malignancy in cancer. In the previous project, it was observed that Mn alters gene expression of metal transporters, favoring the accumulation of this elem…
ISEF · 2025
Earth and Environmental Sciences
The widespread use of synthetic surfactants in household detergents pose major environmental risks due to chemical persistence of non-biodegradable petrochemicals in ecosystems. However, Sap…
ISEF · 2025
Biomedical and Health Sciences
COVID-19, caused by SARS-CoV-2, has been associated with a range of cardiovascular complications, including arrhythmias and cardiomyopathy. This study investigates how the SARS-CoV-2 spike p…
ISEF · 2025
Translational Medical Science
Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder affecting millions of women worldwide. It is characterized by irregular periods, alopecia, hyperandrogenism, infertility, hirsutis…
ISEF · 2025
Behavioral and Social Sciences
Olfaction or the sense of smell plays a fundamental role in the animal kingdom's survival and may serve a marker for human disease, including mental disorders. This study’s objectives are: 1…
ISEF · 2025
Environmental Engineering
Science of Autonomy: Optimal path planning optimizes maritime navigation by analyzing environmental factors such as ocean currents to determine time-optimal routes in the ocean. I hypothesiz…
ISEF · 2025
Microbiology
Antimicrobial resistance (AMR), often referred to as a “silent pandemic” in scientific discussions, has become one of the most pressing threats to global health. AMR plays a key role in micr…
ISEF · 2025
Environmental Engineering
The high volumetric capacity (53 g H2/L), low toxicity, and ambient stability of formic acid (FA) make it a promising hydrogen carrier, yet efficiently extracting hydrogen in a clean and sca…
ISEF · 2025
Environmental Engineering
The NOAA defines microplastics as "plastic pieces less than five millimeters long." Microplastics have been found from the Mariana Trench to Mount Everest, and from the human brain to the pl…
ISEF · 2025
Systems Software
In the recent decade, autonomous systems like self-driving cars, drones, and robots have become widely used. They rely heavily on 3D perception of the surrounding environment and mapping tec…
ISEF · 2025
Systems Software
As cyber-attacks become increasingly common (72% increase from 2021), and as losses from cybercrime grow each year ($10.5 trillion by 2025), it is more important than ever for organizations…
ISEF · 2025
Physics and Astronomy
This study proposes a methodology to characterize asteroid 1777 Gehrels through its light curve and to derive an exploration orbit using reinforcement learning. A total of 120 images were co…
ISEF · 2025
Engineering Technology: Statics & Dynamics
The Rio Grande Gorge bridge has an average of six suicides/year, as compared to 13.6 suicides/year (Atkins-Witmer, Woods, 2013) for the Golden Gate bridge. Per capita, this is a comparable s…
ISEF · 2025
Engineering Technology: Statics & Dynamics
Each time a rocket is launched into the Earth's atmosphere it uses several thousands of gallons of chemical fuel per second. These chemical fuels, when being used in such large quantities, c…
ISEF · 2025
Materials Science
With more than 360 million tons of plastic produced each year, plastic pollution has become a critical issue as plastics accumulate in our environment and inside us; microplastics are even k…
ISEF · 2025
Microbiology
Quorum Sensing (QS) is a bacterial communication pathway that mediates population-based activity activities such as virulence, motility, conjugation, and biofilm formation. Specifically, QS-…