Browse real student projects, abstracts, and awards.
ISEF · 2025
Environmental Engineering
In 2022, global carbon dioxide emissions reached an estimated 36.8 billion metric tons, which has had a profound impact on climate change and environmental deterioration. The overall CO2 con…
ISEF · 2025
Environmental Engineering
The purpose of this project was to engineer a cyanobacteria mitigation device and test how deployed, regulated concentrations of hydrogen peroxide could kill cyanobacteria and how Great Mull…
ISEF · 2025
Biomedical and Health Sciences
Asymptomatic intracranial hemorrhage (aICH) patients present with either a decrease or no change in NIHSS scores, which may falsely indicate clinical improvement in the days leading up to th…
ISEF · 2025
Animal Sciences
Alzheimer’s disease (AD) is the 7th leading cause of death worldwide. It is characterized by the buildup of amyloid-ß plaques that trigger neuroinflammation and increase oxidative stress, ca…
ISEF · 2025
Systems Software
Alzheimer's disease presents a real challenge for caregivers, often leading to high stress and mental strain, as shown by Kim et al., 2021, Vu et al., 2022, and Hosseini, 2022. Informal care…
ISEF · 2025
Cellular and Molecular Biology
Translation initiation in human embryonic stem cells (hESCs) is governed by a delicate balance among canonical, cap-dependent and alternative pathways. This study dissects the roles of eIF4G…
ISEF · 2025
Mathematics
How likely is it that we are one of the luckiest among many evolutionary possibilities? The NK model, a mathematical exemplar describing Wright's fitness landscapes, has provided great insig…
ISEF · 2025
Chemistry
Global carbon dioxide (CO2) emissions, exceeding 37 billion tons annually, are intensifying environmental crises and threatening public safety. Electrochemical CO2 reduction reaction (eCO2RR…
ISEF · 2025
Computational Biology and Bioinformatics
Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by pervasive patterns of inattention, hyperactivity, and impulsivity that are inappropriate for…
ISEF · 2025
Translational Medical Science
Osteosarcoma (OS) is an aggressive bone cancer with poor survival rates due to chemoresistance. Chemotherapy, the main treatment, often fails as OS cells become resistant, leading to tumor g…
ISEF · 2025
Translational Medical Science
One of the most common complications of chemotherapy treatment is febrile neutropenia (FN), affecting 50% of patients with a mortality rate as high as 21%. Oftentimes, fever is the first and…
ISEF · 2025
Systems Software
With the rise of Generative AI (Gen AI), academic dishonesty in the classroom has skyrocketed, with over 90% of students now admitting to using it for schoolwork. While Gen AI offers various…
ISEF · 2025
Systems Software
Efficient traffic navigation algorithms are vital for reducing congestion, emissions, and delays in modern cities. Yet, existing systems use “selfish” routing — optimizing individual travel…
ISEF · 2025
Robotics and Intelligent Machines
Coral reefs are vital marine ecosystems that face mounting environmental challenges, including climate change and pollution, which contribute to coral degradation and bleaching. This project…
ISEF · 2025
Computational Biology and Bioinformatics
5-Fluorouracil (5-FU), a common chemotherapy for solid tumors, is metabolized primarily by dihydropyrimidine dehydrogenase (DPD), encoded by the DPYD gene. With > 200 known variants, individ…
ISEF · 2025
Computational Biology and Bioinformatics
Biologists often take sequential 2D images at different heights to study biological structures. Last year, one of us wrote software that creates a 3D rendering from these images. This year,…
ISEF · 2025
Robotics and Intelligent Machines
AutoMates presents a novel intelligent solution for multiple intelligent agents to self-learn performing complex, hard-to-optimize, and unpredictable tasks. It does this using a) a novel ite…
ISEF · 2025
Engineering Technology: Statics & Dynamics
A prevailing issue among the geriatric population is the difficulty of managing medication. With 36% of Americans over 65 using at least five prescription medications and 3% experiencing dem…
ISEF · 2025
Robotics and Intelligent Machines
Amyotrophic Lateral Sclerosis (ALS) patients with severe motor and speech impairments often rely on eye movements and assistive technology to move and communicate. However, current smart whe…
ISEF · 2025
Biomedical Engineering
Uncontrolled bleeding is a leading cause of preventable death in both civilian and combat trauma cases. My project, Smart Tourniquets, explores the development of an automatic tourniquet des…
ISEF · 2025
Behavioral and Social Sciences
Throughout school, I have only ever encountered the topic of diabetes once. That was in sixth grade; even then, there was only a paragraph about the disease. As I have matured and accepted m…
ISEF · 2025
Embedded Systems
On average, every eight minutes a car hits a pedestrian, and every 70 minutes one is killed. The elderly, the hard of hearing, and those listening to music while exercising are at an increas…
ISEF · 2025
Physics and Astronomy
The ADMX experiment utilizes a microwave haloscope to directly detect axions, a theoretical particle that is the proposed solution for the Strong CP problem and a strong candidate for dark m…
ISEF · 2025
Biomedical and Health Sciences
Understanding the transcriptomic association of athletic performance, including VO2max, is critical for elucidating the interplay between molecular biology and exercise outcomes. Predicting…
ISEF · 2025
Environmental Engineering
Postpartum women often use cotton pads with endocrine-disrupting chemicals, risking secondary infertility and solid waste accumulation. Bast fibers require less water to cultivate, biodegrad…
ISEF · 2025
Animal Sciences
The Varroa mite is the most dangerous honey bee parasite and imperils global beekeeping, causing yield reductions over 40% and estimated annual economic losses of billions of dollars. Curren…
ISEF · 2025
Animal Sciences
The purpose of this study was to investigate whether bacteria found in livestock at stock shows are developing resistance to common antibiotics. This research aims to provide insights into a…
ISEF · 2025
Animal Sciences
Maintaining healthy honey bee (Apis mellifera) populations is critical for biodiversity and agricultural sustainability. However, neonicotinoid pesticides such as imidacloprid pose significa…
ISEF · 2025
Materials Science
The Biodegradable Algae plastic project was designed to find a solution for the world's aggressive plastic waste problem. After doing research on potential materials, it was found that Chond…
ISEF · 2025
Biomedical Engineering
Biodegradable bone scaffolds have the potential to be an alternative treatment for bone grafts. Infusion with antimicrobial factors could provide a controllable release mechanism for targete…