Browse real student projects, abstracts, and awards.
ISEF · 2026
Biochemistry
Neurodegenerative diseases such as Parkinson's & Alzheimer's are increasing worldwide exponentially. While many studies focus on factors such as aging & genetics, the effects of environmenta…
ISEF · 2026
Biomedical and Health Sciences
Dehydration is one of the leading causes of hospital admissions. Evaluations to measure hydration status in clinical settings utilize methods such as blood tests, urinalysis, and skin turgor…
ISEF · 2026
Materials Science
Angioplasty procedures rely on stents to keep arteries open, but traditional metal stents remain permanently in the body and can lead to long-term complications. Biodegradable stents offer a…
ISEF · 2026
Microbiology
Vitamin A deficiency (VAD) is a major global health crisis affecting approximately 19 million pregnant women and 30 million children under the age of five, with over 50% of cases from rural…
ISEF · 2026
Mathematics
Globally, water scarcity affects 75% of the population. Agriculture accounts for 70% of global freshwater withdrawals, and farmers use unreliable, reactive irrigation systems. This project i…
ISEF · 2026
Embedded Systems
3D scanning of microscopic objects currently relies on expensive laser scanning microscopes, that can be inefficient or unusable in scenarios requiring multi-angle views or the analysis of s…
ISEF · 2026
Animal Sciences
An unusual population of Camponotus (Mayr, 1861) was investigated, initially suspected to belong to the complex Camponotus sansabeanus (Buckley, 1866). Worker and gyne specimens were used in…
ISEF · 2026
Microbiology
Antibiotic are medicines used to kill or inhibit bacterial growth. Due to overuse, antibiotics are becoming less effective. Lactic acid bacteria (LAB) are a group of bacteria which produce a…
ISEF · 2026
Microbiology
In the United Stated more than 2.8 million antimicrobial-resistant infections occur each year. According to CDC's (2025) AR Threats Report, more than 35,000 people die of this infection and…
ISEF · 2026
Computational Biology and Bioinformatics
Rheumatoid arthritis (RA) is an autoimmune disease affecting approximately 18 million people worldwide. Many treatments rely on monoclonal antibody drugs that block inflammatory signals such…
ISEF · 2026
Microbiology
Food waste accounts for 58% of methane emissions from municipal solid waste landfills (MSWLF), one of the top three sources of greenhouse gas emissions globally. Over 96% of MSWLFs lack deco…
ISEF · 2026
Translational Medical Science
Airborne Neurotropic Viruses (ANVs) are emergent invasive neuropathogens, affecting 300-500 million people and being responsible for >700,000 deaths annually. Early neurotropic transcriptomi…
ISEF · 2026
Biomedical and Health Sciences
Diabetes mellitus is a metabolic disorder resulting in the dysregulation of blood glucose (BG), affecting more than 14% of adults. BG is typically regulated by the pancreatic hormone insulin…
ISEF · 2026
Robotics and Intelligent Machines
Individuals with non-fluent aphasia, such as Broca's aphasia, face profound communication barriers due to impaired verbal expression. Traditional assistive tools often rely on static image d…
ISEF · 2026
Animal Sciences
With 5.6 billion pounds of pesticides entering ecosystems annually, traditional monitoring methods such as soil and water sampling cannot cover large areas, cost $500–600 per sample, and tak…
ISEF · 2026
Engineering Technology: Statics & Dynamics
20% of total energy consumption is used to merely overcome friction (Holmberg and Erdemir, 2017). Friction comes from all places, with new rolling bearings accounting for over 420 terawatt h…
ISEF · 2026
Physics and Astronomy
The goal of the research is to develop a method for rapid, non-contact surface microstructure analysis based on laser speckle imaging. The research aims to identify quantitative relationship…
ISEF · 2026
Technology Enhances the Arts
Vibrotactile stimuli are vibrations that can be felt through the sense of touch. They are commonly used in haptic systems and assistive technologies. This project explores the various potent…
ISEF · 2026
Physics and Astronomy
Standard rulers are astronomical objects with known intrinsic sizes whose apparent angular sizes can be used to determine their distance. Black holes (BHs) represent a potential standard rul…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Turbulence, one of the biggest issues in aerospace engineering, is categorized as the chaotic airflow and the rapid changes in airflow. The wing response to that flow of air is imperative in…
ISEF · 2026
Engineering Technology: Statics & Dynamics
Current methods of metal additive manufacturing (AM) typically require high-power laser or arc technology to melt metal into desired forms (powder bed fusion and wire arc AM, respectively).…
ISEF · 2026
Software Design
As the effects of climate change intensify, heatwaves become a pressing issue, underscoring the need for risk mitigation and preparedness. Nationally, the U.S. Centers for Disease Control an…
ISEF · 2026
Translational Medical Science
Parkinson’s Disease (PD) is a chronic and progressive neurodegenerative disease associated with the deterioration of motor control and cognitive function as age advances. Representing the fa…
ISEF · 2026
Biochemistry
PFOA (Perfluorooctanoic acid), a type of PFAS (per- and polyfluoroalkyl substances), is a chemical used in the manufacturing of many products. PFOA is classified as an IARC Group 1 carcinoge…
ISEF · 2026
Cellular and Molecular Biology
?9-tetrahydrocannabinol (THC) is among the most prevalent psychoactive drugs in the United States, with nearly 20 million users each day. Yet, detection capabilities remain limited for roads…
ISEF · 2026
Biochemistry
Purpose: Drug overdoses have become a public health crisis in the United States, with approximately 68% involving opioids, particularly synthetic opioids such as fentanyl. Because overdose c…
ISEF · 2026
Environmental Engineering
Urban flooding is escalating into a critical global challenge, driven by the inability of conventional drainage inlets to handle increasing rainfall intensities due to rapid urbanization and…
ISEF · 2026
Physics and Astronomy
Quantum computers promise computational advantages beyond classical limits. Although reported gate fidelities are high for modern devices, widely thought to indicate high performance, they d…
ISEF · 2026
Earth and Environmental Sciences
Cyanobacterial harmful algal blooms (HABs) pose threats to aquatic ecosystems and public health, yet existing prediction models rely on single-variable correlative thresholds that fail to ca…
ISEF · 2026
Materials Science
Artificial intelligence hardware is increasingly constrained by the energy cost of data movement: a single DRAM access can consume 200× the energy of an on-chip compute operation. Neuromorph…