20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2025
Computational Biology and Bioinformatics
5-Fluorouracil (5-FU), a common chemotherapy for solid tumors, is metabolized primarily by dihydropyrimidine dehydrogenase (DPD), encoded by the DPYD gene. With > 200 known variants, individ…
ISEF · 2025
Computational Biology and Bioinformatics
Biologists often take sequential 2D images at different heights to study biological structures. Last year, one of us wrote software that creates a 3D rendering from these images. This year,…
ISEF · 2025
Robotics and Intelligent Machines
AutoMates presents a novel intelligent solution for multiple intelligent agents to self-learn performing complex, hard-to-optimize, and unpredictable tasks. It does this using a) a novel ite…
ISEF · 2025
Engineering Technology: Statics & Dynamics
A prevailing issue among the geriatric population is the difficulty of managing medication. With 36% of Americans over 65 using at least five prescription medications and 3% experiencing dem…
ISEF · 2025
Robotics and Intelligent Machines
Amyotrophic Lateral Sclerosis (ALS) patients with severe motor and speech impairments often rely on eye movements and assistive technology to move and communicate. However, current smart whe…
ISEF · 2025
Biomedical Engineering
Uncontrolled bleeding is a leading cause of preventable death in both civilian and combat trauma cases. My project, Smart Tourniquets, explores the development of an automatic tourniquet des…
ISEF · 2025
Behavioral and Social Sciences
Throughout school, I have only ever encountered the topic of diabetes once. That was in sixth grade; even then, there was only a paragraph about the disease. As I have matured and accepted m…
ISEF · 2025
Embedded Systems
On average, every eight minutes a car hits a pedestrian, and every 70 minutes one is killed. The elderly, the hard of hearing, and those listening to music while exercising are at an increas…
ISEF · 2025
Physics and Astronomy
The ADMX experiment utilizes a microwave haloscope to directly detect axions, a theoretical particle that is the proposed solution for the Strong CP problem and a strong candidate for dark m…
ISEF · 2025
Biomedical and Health Sciences
Understanding the transcriptomic association of athletic performance, including VO2max, is critical for elucidating the interplay between molecular biology and exercise outcomes. Predicting…
ISEF · 2025
Environmental Engineering
Postpartum women often use cotton pads with endocrine-disrupting chemicals, risking secondary infertility and solid waste accumulation. Bast fibers require less water to cultivate, biodegrad…
ISEF · 2025
Animal Sciences
The Varroa mite is the most dangerous honey bee parasite and imperils global beekeeping, causing yield reductions over 40% and estimated annual economic losses of billions of dollars. Curren…
ISEF · 2025
Animal Sciences
The purpose of this study was to investigate whether bacteria found in livestock at stock shows are developing resistance to common antibiotics. This research aims to provide insights into a…
ISEF · 2025
Animal Sciences
Maintaining healthy honey bee (Apis mellifera) populations is critical for biodiversity and agricultural sustainability. However, neonicotinoid pesticides such as imidacloprid pose significa…
ISEF · 2025
Materials Science
The Biodegradable Algae plastic project was designed to find a solution for the world's aggressive plastic waste problem. After doing research on potential materials, it was found that Chond…
ISEF · 2025
Biomedical Engineering
Biodegradable bone scaffolds have the potential to be an alternative treatment for bone grafts. Infusion with antimicrobial factors could provide a controllable release mechanism for targete…
ISEF · 2025
Plant Sciences
Japanese Knotweed (Fallopia japonica) is a highly dominant alien weed species that is increasingly abundant across the Americas and Europe, possessing several potentially allelopathic plant…
ISEF · 2025
Earth and Environmental Sciences
By the year 2050, it is estimated that cumulative plastic production will reach 34 billion tons (Bt), and at pace with the current consumption rate, around 12 Bt of per week (PW) will find t…
ISEF · 2025
Cellular and Molecular Biology
Uveal melanoma, cancer of the melanin-producing cells in the eye, is the most common type of intraocular cancer in adults. Approximately half the patients develop metastatic disease, which h…
ISEF · 2025
Environmental Engineering
The overuse of fossil fuels and nitrogen fertilizers presents a significant environmental burden, necessitating sustainable alternatives. While mainstream algal biomass fuels derived from mi…
ISEF · 2025
Engineering Technology: Statics & Dynamics
In construction or any fields that involve blasting, workers often measure rock hardness and assess slope stability on steep, high-altitude surfaces, requiring high-risk suspended tasks. The…
ISEF · 2025
Biomedical Engineering
Maintaining optimal hydration and health is integral for overall well-being and daily functioning, particularly for space travel (flight). This project was designed to provide accurate and c…
ISEF · 2025
Animal Sciences
This study aims to enhance blue swimming crab larval survival for conservation before release into natural habitats, reducing environmental impact. Blue swimming crabs (Portunus pelagicus) p…
ISEF · 2025
Materials Science
The growth of the plastic industry since the 1950s has resulted in an alarming accumulation of plastic waste, with an estimated 8.3 million tonnes of plastic produced globally and 6.3 millio…
ISEF · 2025
Environmental Engineering
Noise pollution and ship-induced wakes not only harm wildlife and erode shores, but also cost the shipping industry billions of dollars in traffic disruptions. Aquatic insects and penguins t…
ISEF · 2025
Biochemistry
Nitric oxide sensing proteins (NosPs) have been studied as important signaling molecules in various organisms. Particularly in Pseudomonas aeruginosa, NosP plays a role in heme binding and c…
ISEF · 2025
Animal Sciences
Quantitative analysis of colouration in specimens has always posed to be a challenge in taxonomy, and is yet often crucial as morphological traits may sometimes reveal variations not observe…
ISEF · 2025
Biomedical Engineering
Cardiovascular diseases remain the leading cause of mortality worldwide, with most conditions requiring vascular stents to restore blood flow. However, complications such as restenosis—the r…
ISEF · 2025
Energy: Sustainable Materials and Design
With a high theoretical capacity (2596 mAh/g) and a safe lithiation potential (0.7V), black phosphorus (BP) demonstrates potential for fast charging lithium-ion batteries (LIBs). However, it…
ISEF · 2025
Systems Software
This paper introduces QyberShield, a new algorithm that integrates the strengths of blockchain technology and recent advancements in quantum computing. The algorithm is designed to leverage…