Browse real student projects, abstracts, and awards.
ISEF · 2025
Cellular and Molecular Biology
Neurodegenerative diseases (NDDs), like Alzheimer's and Parkinson's, are characterized by impairment of synaptic plasticity, the brain's capacity to rewire connections critical for cognition…
ISEF · 2025
Energy: Sustainable Materials and Design
Further optimization of renewable energy systems is crucial for efforts towards developing a sustainable future. Recently, offshore wind has become one of the most rapidly advancing solution…
ISEF · 2025
Engineering Technology: Statics & Dynamics
Across the world, hundreds of millions of people are affected by a global inability to meet construction demands. In particular, widespread infrastructure inadequacy that will reach $100 tri…
ISEF · 2025
Behavioral and Social Sciences
This project introduces an Artificial intelligence powered web application designed to assist in the early detection of Autism Spectrum Disorder (ASD) through facial expression analysis. Usi…
ISEF · 2025
Environmental Engineering
The vast majority of research vessels are restricted by their large size and their need to be captained, making it difficult, if not impossible, for remote, shallow, and hard-to-reach locati…
ISEF · 2025
Biomedical and Health Sciences
Each year, over 10,000,000 people lose their lives to cancer. Many current cancer therapies cause deleterious side effects for patients and have an inordinate cost, ultimately leading to pat…
ISEF · 2025
Systems Software
A critical goal in robotics and autonomy is to teach robots to adapt to real-world collaborative tasks, particularly in automatic assembly. The ability of a robot to understand the original…
ISEF · 2025
Behavioral and Social Sciences
This project primarily aimed to quantitatively assess gender differences in the attribution of certain mental disorders to certain gender identities. It secondarily assessed gender differenc…
ISEF · 2025
Systems Software
The purpose of this engineering design project is to create and optimize an AI-based tool that uses a patient's textual descriptions of symptoms to predict the potential severity of their co…
ISEF · 2025
Plant Sciences
Aquaponics is a process of producing food through a symbiotic relationship between fish, which provide nutrients, and plants, which purify water. This project assesses the effectiveness of n…
ISEF · 2025
Cellular and Molecular Biology
Metastatic prostate cancer (mPC) stands second in cancer-related mortality among men. As current treatment options are largely palliative, there is a dire need for novel therapeutic targets…
ISEF · 2025
Microbiology
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is once again the world's deadliest infectious disease, after being replaced by COVID-19 for three years. The only approved vaccine f…
ISEF · 2025
Microbiology
As artificial sweetener consumption rises, environmental contamination by sucralose has become a growing concern due to its persistence in aquatic ecosystems. Previous research has shown tha…
ISEF · 2025
Microbiology
The Cerrado, Brazil's second-largest biome, occupies 23% of the national territory and plays a crucial role in the agricultural economy, particularly in Mato Grosso do Sul, where pastures su…
ISEF · 2025
Translational Medical Science
Study Objective: The primary aim of this study was to investigate how P2X1 receptor activation in lung adenocarcinoma (LA) influences the tumor microenvironment, particularly in promoting pr…
ISEF · 2025
Physics and Astronomy
A transit occurs when an exoplanet blocks the light from its host star to cause a unique dimming. The Transiting Exoplanet Survey Satellite (TESS) is an all-sky scanning space telescope that…
ISEF · 2025
Environmental Engineering
In 2022, global carbon dioxide emissions reached an estimated 36.8 billion metric tons, which has had a profound impact on climate change and environmental deterioration. The overall CO2 con…
ISEF · 2025
Environmental Engineering
The purpose of this project was to engineer a cyanobacteria mitigation device and test how deployed, regulated concentrations of hydrogen peroxide could kill cyanobacteria and how Great Mull…
ISEF · 2025
Biomedical and Health Sciences
Asymptomatic intracranial hemorrhage (aICH) patients present with either a decrease or no change in NIHSS scores, which may falsely indicate clinical improvement in the days leading up to th…
ISEF · 2025
Animal Sciences
Alzheimer’s disease (AD) is the 7th leading cause of death worldwide. It is characterized by the buildup of amyloid-ß plaques that trigger neuroinflammation and increase oxidative stress, ca…
ISEF · 2025
Systems Software
Alzheimer's disease presents a real challenge for caregivers, often leading to high stress and mental strain, as shown by Kim et al., 2021, Vu et al., 2022, and Hosseini, 2022. Informal care…
ISEF · 2025
Cellular and Molecular Biology
Translation initiation in human embryonic stem cells (hESCs) is governed by a delicate balance among canonical, cap-dependent and alternative pathways. This study dissects the roles of eIF4G…
ISEF · 2025
Mathematics
How likely is it that we are one of the luckiest among many evolutionary possibilities? The NK model, a mathematical exemplar describing Wright's fitness landscapes, has provided great insig…
ISEF · 2025
Chemistry
Global carbon dioxide (CO2) emissions, exceeding 37 billion tons annually, are intensifying environmental crises and threatening public safety. Electrochemical CO2 reduction reaction (eCO2RR…
ISEF · 2025
Computational Biology and Bioinformatics
Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by pervasive patterns of inattention, hyperactivity, and impulsivity that are inappropriate for…
ISEF · 2025
Translational Medical Science
Osteosarcoma (OS) is an aggressive bone cancer with poor survival rates due to chemoresistance. Chemotherapy, the main treatment, often fails as OS cells become resistant, leading to tumor g…
ISEF · 2025
Translational Medical Science
One of the most common complications of chemotherapy treatment is febrile neutropenia (FN), affecting 50% of patients with a mortality rate as high as 21%. Oftentimes, fever is the first and…
ISEF · 2025
Systems Software
With the rise of Generative AI (Gen AI), academic dishonesty in the classroom has skyrocketed, with over 90% of students now admitting to using it for schoolwork. While Gen AI offers various…
ISEF · 2025
Systems Software
Efficient traffic navigation algorithms are vital for reducing congestion, emissions, and delays in modern cities. Yet, existing systems use “selfish” routing — optimizing individual travel…
ISEF · 2025
Robotics and Intelligent Machines
Coral reefs are vital marine ecosystems that face mounting environmental challenges, including climate change and pollution, which contribute to coral degradation and bleaching. This project…