Browse real student projects, abstracts, and awards.
ISEF · 2025
Biomedical and Health Sciences
Duchenne Muscular Dystrophy (DMD) is an inherited X-linked disease with an incidence of 1:3,600. Patients become weak at 2-3 years old with progression to respiratory failure and death in th…
ISEF · 2025
Biomedical Engineering
Lung cancer (LC), responsible for one in five cancer-related deaths, remains a major public health challenge (American Lung Association, 2024). Early detection is critical, as 5-year surviva…
ISEF · 2025
Microbiology
One of the most important steps in the overall workflow of manufacturing a drug is ensuring that the mice in which the drug is tested are healthy; unhealthy or sick mice will provide inaccur…
ISEF · 2025
Biomedical Engineering
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, killing about 17.9 million people annually. Most CVDs are age-related, driven by gradual damage to blood vessels, als…
ISEF · 2025
Computational Biology and Bioinformatics
The growing prevalence of neurodegenerative diseases underscores the importance of improved diagnostic accuracy. Many proposed Clinical Decision Support Systems (CDSS) have low interpretabil…
ISEF · 2025
Technology Enhances the Arts
OpenAI's ChatGPT has blurred the line between human and AI-written text, challenging academia's ability to verify authorship. Existing AI detection systems fail with paraphrased content or m…
ISEF · 2025
Biomedical and Health Sciences
Colorectal cancer (CRC) is the third most common cancer globally, with over 1.9 million new cases and nearly 1 million deaths annually. The incidence of early-onset CRC, defined as cancer oc…
ISEF · 2025
Biomedical and Health Sciences
Immune checkpoint inhibitors (ICIs) have emerged as a promising therapy for late-stage lung cancer. However, the response rate to ICIs remains low. As a result, there is a need to better und…
ISEF · 2025
Physics and Astronomy
Atmospheric transmission spectroscopy - a method to detect molecular signals in a planet’s atmosphere - could help humankind explore how the universe has evolved to support life on exoplanet…
ISEF · 2025
Animal Sciences
Birds generate calls and songs with distinct frequency patterns. Spectrograms have long been used to visualize those sound patterns by mapping changes in pitch and amplitude over time. While…
ISEF · 2025
Translational Medical Science
Metabolic disorders and malnutrition remain critical health concerns, often undiagnosed due to invasive, costly, and inaccessible testing methods. VitalEdge is a novel non-invasive biosensor…
ISEF · 2025
Embedded Systems
Cardiovascular and respiratory diseases make up 2 of the 3 leading causes of death globally amounting to more than 23 million people. More than half of these deaths are preventable with earl…
ISEF · 2025
Systems Software
In recent years, advancement in artificial intelligence and speech synthesis technologies, have made it possible to clone human voices with remarkable accuracy. While this opens many benefic…
ISEF · 2025
Embedded Systems
Artificial Intelligence (AI) has become a cornerstone of global innovation. However, current digital hardware, such as GPUs, faces critical computational bottlenecks with the growth of next-…
ISEF · 2025
Environmental Engineering
The total generation of solid waste in the US is 292.4 million tons/year, EPA (2024), and its processing requires the use of one of the least efficient vehicles on the road, the garbage truc…
ISEF · 2025
Environmental Engineering
Purpose: Design a vacuum unit suitable for integration into multiple water heating systems to prevent the waste of cold water that comes first when we want to use hot water in the taps in th…
ISEF · 2025
Environmental Engineering
Oil pollution on water surfaces remains a critical environmental challenge, with over 20 million liters of oil discharged into aquatic ecosystems each year. These spills endanger marine life…
ISEF · 2025
Environmental Engineering
Pumped storage hydropower (PSH) is a battery free, energy storage system that uses the potential energy of water to generate hydroelectric power. Our hypothesis was that we would be able to…
ISEF · 2025
Physics and Astronomy
Recent discoveries like GJ 9827 d's water-rich atmosphere have brought to light an understudied class of exoplanets—water worlds. The discovery of water in this exoplanet atmosphere simultan…
ISEF · 2025
Earth and Environmental Sciences
The El Niño-Southern Oscillation (ENSO) is a significant climate phenomenon with far-reaching impacts on global weather patterns, ecosystems, and economies. This study aims to enhance ENSO f…
ISEF · 2025
Environmental Engineering
Oil spills pose serious threats to marine ecosystems, disrupting biodiversity and causing widespread environmental and economic damage. Conventional cleanup techniques—such as booms, skimmer…
ISEF · 2025
Biomedical Engineering
The continuous monitoring of human physiological health without the presence of a doctor has been a recent subject of innovation. A popular method for detecting various factors involves anal…
ISEF · 2025
Biomedical Engineering
Traditional auscultation devices and methods have inherent limitations in spatially localizing body sounds and suppressing interference—restricting their diagnostic potential. This project d…
ISEF · 2025
Technology Enhances the Arts
Communication between the hearing impaired and the general people has long been an unresolved issue. Although sign language can solve this problem to some extent, sign language becomes ineff…
ISEF · 2025
Earth and Environmental Sciences
Wastewater runoff from textile industries – especially in regions with high amounts of both textile and agricultural production (typically east-Asian countries) – can seep into groundwater a…
ISEF · 2025
Systems Software
Artificial intelligence has developed quickly and improved daily life for the majority of individuals, yet accessibility challenges persist for the visually impaired. Existing assistive tech…
ISEF · 2025
Robotics and Intelligent Machines
Pneumonia is a potentially lethal lung disease characterized by inflammation of the alveoli. Chest X-ray (CXR) imaging is the primary diagnostic tool, but human interpretation requires signi…
ISEF · 2025
Materials Science
This study investigated the effects of temperature, mordant additives, and pH on the colorfastness of natural substantive dyes. The hypothesis proposed that alum would enhance colorfastness…
ISEF · 2025
Environmental Engineering
Access to treated water is a challenge in many communities around the world. Globally, 2.2 billion people do not have access to drinking water. In Brazil, over 33 million people face this pr…
ISEF · 2025
Robotics and Intelligent Machines
The aim of this project is to determine how having two methods of movement (wheels and legs) affects the movement capabilities of a robot. First, a robot with both wheeled and quadruped syst…