Browse real student projects, abstracts, and awards.
ISEF · 2025
Biochemistry
Hyperactive Wnt signalling causes over 90% of colorectal and 50% of breast cancers. It is driven by excessive nuclear translocation of mutant ß-catenin (ArmS10 in Drosophila), yet the exact…
ISEF · 2025
Energy: Sustainable Materials and Design
Air batteries are an emerging technology for renewable energy storage. Their distinct chemical properties convert atmospheric oxygen into viable electric energy. Currently, air batteries are…
ISEF · 2025
Mathematics
This project investigates the representation of polygons through the roots of unity. Since the points in the complex graph of power functions lead to equidistant solutions, they can then be…
ISEF · 2025
Animal Sciences
Most species of newts in the genus Cynops live in southern China, while two species in Japan. One Japanese species is the Japanese fire-bellied newt (Cynops pyrrhogaster), which is the north…
ISEF · 2025
Environmental Engineering
Plastic waste from bottles is a major environmental issue. This study explores using recycled plastic bottles in concrete to create a lightweight, durable, and eco-friendly material. The pro…
ISEF · 2025
Biomedical and Health Sciences
Botulinum neurotoxin type A (BoNT/A) represents a serious biological threat to global public health due to its extreme toxicity and its prolonged persistence. Recently, several camelid singl…
ISEF · 2025
Animal Sciences
Freshwater mussels of the order Unionoida is a spawning ground for bitterlings and are therefore an important species in freshwater ecosystems. However, they face global extinction threat du…
ISEF · 2025
Biomedical Engineering
Respiratory issues like Interstitial Lung Diseases (ILDs), Occupational and Environmental Lung Diseases are difficult to identify because their symptoms closely resemble other musculoskeleta…
ISEF · 2025
Technology Enhances the Arts
Artworks are one of the most important parts of cultural heritage. Unfortunately, they are often exposed to a lot of damage and are altered by threats like fire, water, fading, tearing, and…
ISEF · 2025
Translational Medical Science
Diabetic Retinopathy (DR) is a serious complication associated with diabetes that can lead to vision loss in middle-aged and older adults. Caused by chronic high blood sugar levels, poor gly…
ISEF · 2025
Microbiology
Oil contamination in soil poses a significant threat to ecosystems and human health, underscoring the need for effective remediation strategies. This study aimed to isolate and identify oil-…
ISEF · 2025
Plant Sciences
Marine microalgae are responsible for nearly 50% of their ecosystem's oxygen production and primary productivity, making them essential in the marine environment. These organisms also play a…
ISEF · 2025
Mathematics
Lothar Collatz defined a function on natural numbers: divide x by 2 when it is even, multiply by three and add one otherwise. He conjectured that repeated application of this function to any…
ISEF · 2025
Biomedical Engineering
Choroidal melanoma is a rare cancerous eye tumor that affects approximately six in one million Caucasian individuals (Soliman et al., 2023). About 50% of patients develop metastasis, meaning…
ISEF · 2025
Robotics and Intelligent Machines
Reliable and timely access to medical supplies is a significant challenge in regions with poor infrastructures and frequent natural disasters. Drones present a promising solution by enabling…
ISEF · 2025
Biomedical Engineering
Diabetes is one of the leading causes of death and chronic disease in the United States. Current glucose monitoring devices require painful blood sticks that lead to poor monitoring adherenc…
ISEF · 2025
Engineering Technology: Statics & Dynamics
The aerospike rocket engine, developed in the late 1960s, was designed to address a significant limitation of traditional bell rocket engines: inefficient exhaust gas expansion across varyin…
ISEF · 2025
Physics and Astronomy
Shear-thickening fluids (STFs) were added to Kevlar to find their effect on force absorbed by material over a short period of time. This could be used in spacesuits to protect against microm…
ISEF · 2025
Biomedical Engineering
The current healthcare workforce shortage requires us to reevaluate our approach to training future healthcare professionals. This study assesses a virtual reality application with gamificat…
ISEF · 2025
Physics and Astronomy
After reading that exposure to high-frequency radio waves could have adverse effects on humans and the environment, my interest was piqued in the possibility of minimizing exposure to this n…
ISEF · 2025
Biomedical Engineering
Atrial fibrillation (AF), the most prevalent heart arrhythmia affecting over 60 million people globally, is expected to double by 2050. As a leading contributor to 15-20% of all strokes, AF…
ISEF · 2025
Robotics and Intelligent Machines
Rip currents pose significant hazards to beach safety. They are unpredictable and strong, quickly pulling swimmers away from shore, often leading to drowning. To mitigate the harm of rip cur…
ISEF · 2025
Cellular and Molecular Biology
Finding a treatment for breast cancer has been a persisting need as one in eight women will experience this disease in her lifetime. Current treatment options present harmful side effects an…
ISEF · 2025
Computational Biology and Bioinformatics
The m6a methylation of the TAR region promotes neuroinflammation in HIV-1 neurocognitive disorders. This is facilitated by the RBM15 protein recognizing and binding U-rich bulges to act as a…
ISEF · 2025
Biochemistry
DNA replication is essential for the accurate transmission of genetic information during cell division. The Rothmund-Thomson syndrome helicase (RECQ4) plays a crucial role in replication ini…
ISEF · 2025
Animal Sciences
Bumblebees are social insects: one queen and many worker bees live in the nest. In the Japanese bumblebee Bombus ignitus, the queen lays fertilized diploid eggs that develop into female work…
ISEF · 2025
Physics and Astronomy
In the aftermath of tragedies like the Surfside Condo Collapse of 2021, the necessity for long-term monitoring methods to detect structural deterioration has significantly increased. Mechani…
ISEF · 2025
Biomedical and Health Sciences
Cardiac complications associated with SARS-CoV-2 infection include arrhythmias, myocarditis, and heart failure. However, the pathogenesis underlying COVID-19-induced cardiac dysfunction rema…
ISEF · 2025
Cellular and Molecular Biology
Manganese is a central promoter of malignancy in cancer. In the previous project, it was observed that Mn alters gene expression of metal transporters, favoring the accumulation of this elem…
ISEF · 2025
Earth and Environmental Sciences
The widespread use of synthetic surfactants in household detergents pose major environmental risks due to chemical persistence of non-biodegradable petrochemicals in ecosystems. However, Sap…