Browse real student projects, abstracts, and awards.
ISEF · 2025
Biomedical and Health Sciences
Liposarcoma (LPS) is a form of cancer derived from fat tissue. Despite the fact that the 5 year survival rate for LPS patients with metastasis is only 15%, treatment for LPS hasn’t been adva…
ISEF · 2025
Biomedical and Health Sciences
Preliminary data shows that cigarette smoke is associated with gene expression changes in whole blood and skin. However, little is known about the epigenetic and genetic response to smoking…
ISEF · 2025
Biomedical and Health Sciences
The Body Mass Index carries gender and ethnic bias that will endanger the future of AI diagnosis. The BMI overlooks that people can have the same BMI yet have vastly different body compositi…
ISEF · 2025
Animal Sciences
Climate change and global warming are ongoing issues that impact all ecosystems. They cause many environmental problems like acid rain, habitat degradation, and species range shifts. This ca…
ISEF · 2025
Biomedical and Health Sciences
Intracranial aneurysms (IAs) are a vascular disorder characterized by the bulging of weakened cerebral blood vessel walls. Affecting 166 million people globally, IAs pose a serious risk due…
ISEF · 2025
Behavioral and Social Sciences
Intersubjective realities refer to the belief systems that when accepted by two or more people have real implications for objective reality. The Covid-19 Pandemic was dominated by the emerge…
ISEF · 2025
Materials Science
The purpose of this project was to see how light propagation has an effect on fiber optic cables. The procedures that were used to make this experiment as safe as possible were using a singl…
ISEF · 2025
Microbiology
The rise of multidrug-resistant (MDR) bacteria presents an escalating challenge to traditional antibiotics, causing the exploration of alternative therapeutic strategies. A key mechanism of…
ISEF · 2025
Plant Sciences
The purpose of this project that will be tested in this research will be to see if the two half doses injections of 0.55cc of Oxytetracycline (OTC), an antibacterial agent, will reduce bark…
ISEF · 2025
Microbiology
Epstein Barr Virus (EBV) is a gammaherpesvirus infecting 90% of adults, and is associated with various diseases, including infectious mononucleosis, Hodgkin lymphoma, Burkitt lymphoma, and N…
ISEF · 2025
Biochemistry
This project's aim was to identify the optimal pH (slightly acidic to neutral pH range: pH 5-pH7) at which the enzyme papain works efficiently in the digestion of the different protein subst…
ISEF · 2025
Physics and Astronomy
This experiment investigated the characteristics of the decoherence of qubits in photonic quantum computers and the effects of decoherence on the superimposed state of the qubit. Three diffe…
ISEF · 2025
Behavioral and Social Sciences
Alzheimer’s Disease (AD) is the world’s leading cause of dementia in older populations, impacting more than 6 million individuals in the U.S. alone. Although FDA approved treatment has been…
ISEF · 2025
Earth and Environmental Sciences
Climate changes that include ocean acidification and global warming are serious problems in the ecosystem, affecting marine phytoplankton, including Nannochloropsis oceanica. In the effort t…
ISEF · 2025
Plant Sciences
Coffee and tea are among the world's most popular drinks, containing large quantities of caffeine, a central nervous system stimulant. Many plants have been shown to produce caffeine by usin…
ISEF · 2025
Animal Sciences
Hector’s lantern fish (Lampanyctodes hectoris), a common mesopelagic species along the west coast, is known to be parasitized by the copepod Cardiodectes bellotti, which consumes its host’s…
ISEF · 2025
Biomedical and Health Sciences
As global energy needs have skyrocketed in the past decade, energy byproduct has increased in tandem. Places like Mooresville, North Carolina; Pineville, Indiana; and southeastern Puerto Ric…
ISEF · 2025
Biomedical and Health Sciences
Parkinson’s disease (PD) is a common neurodegenerative disease (NDD) that is characterized by the gradual loss of dopaminergic neurons and progressive motor impairment. Recent studies sugges…
ISEF · 2025
Translational Medical Science
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor prognosis, signifying a pressing need for novel therapeutic strategies. This study investigated the effect of…
ISEF · 2025
Physics and Astronomy
This study’s goal was to determine which pump laser configuration would stimulate type-1 spontaneous parametric down-conversion (SPDC) in beta barium borate (BBO) crystals such that the numb…
ISEF · 2025
Physics and Astronomy
NASA's Kepler Mission has discovered over 5,800 exoplanets in our galaxy, revealing a puzzling phenomenon known as the "radius cliff." The "radius cliff" is a sharp decline in the number of…
ISEF · 2025
Biomedical and Health Sciences
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the progressive degeneration of motor neurons, leading to muscle weakness, paralysis, and ultimatel…
ISEF · 2025
Cellular and Molecular Biology
Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that persistently infects the central nervous system (CNS) of up to a third of the world’s population. In the immune compe…
ISEF · 2025
Cellular and Molecular Biology
Research showed significant changes in the brain of Drosophila melanogaster such as fewer stem cells and smaller brains after knocking out nhes in the brain. Nhes also affect a decline in ag…
ISEF · 2025
Biochemistry
Pancreatic Ductal Adenocarcinoma (PDAC) remains one of the most lethal cancers with a significantly low 5-year survival rate. PDAC is typically diagnosed in individuals over 65, suggesting t…
ISEF · 2025
Biochemistry
Pesticides are used in agriculture to deter plant pests and pathogens, but are known to have a detrimental effect on the environment and ecosystem because of their ability and frequency to k…
ISEF · 2025
Animal Sciences
The project targeted two specific nutrients types, fiber and potassium and see if it has a correlation with methane productivity in cow manure. The goal was to increase the targeted nutrient…
ISEF · 2025
Cellular and Molecular Biology
The endothelium, a layer of cells lining the inner wall of coronary arteries, contributes to blood hemostasis and healthy function of the heart. In coronary artery disease (CAD), endothelial…
ISEF · 2025
Plant Sciences
Crop damage caused by environmental stress and diseases pose a significant challenge to global food security and agricultural sustainability. Conventional chemical treatments can have harmfu…
ISEF · 2025
Translational Medical Science
Lung cancer remains the as the leading cause of cancer-related deaths worldwide, with an estimated 124,730 deaths in the United States alone in 2025. The situation in Hawai?i is especially c…