Browse real student projects, abstracts, and awards.
ISEF · 2014
Mathematics Fourth Award
Muscular dystrophies are heritable, heterogeneous, neuromuscular disorders characterized by deterioration and severe atrophy of skeletal muscle. This disease is caused by mutations in protei…
ISEF · 2014
Mathematics Second Award
In the US alone, 200,000 surgical vascular procedures fail annually, primarily due to restenosis caused by a healing response known as intimal hyperplasia (IH). IH can be attributed to endot…
ISEF · 2014
Mathematics
Pancreatic cancer (PanCA) is the 4th leading cause of cancer-related death in the United States. An estimated 46,420 new cases of pancreatic cancer will be diagnosed in the US in 2014, accor…
ISEF · 2014
Mathematics
Despite tremendous progress in oncology, many treatments such as chemotherapy continue to weaken the immune systems of cancer patients, increasing their susceptibility to infections and othe…
ISEF · 2014
Mathematics Second Award
Alzheimer’s Disease (AD) occurs when aggregated Beta-Amyloid (ABeta) protein causes massive neuronal death, resulting in atrophy of affected brain regions, memory loss, and eventually death.…
ISEF · 2014
Mathematics
Aging followed by death is one of the most fascinating and unexplained phenomena of the studies of life science. Many different theories on why organism age have been established, but no fir…
ISEF · 2014
Mathematics Fourth Award
Cell screening has revolutionized the field of medicine, with hundreds of cancer drugs owing their discovery these techniques. However, current methods involve analyzing population of cells…
ISEF · 2014
Mathematics Fourth Award
A novel nanoparticle (NP) targeted cancer therapy with personalized medicine applications is described. A NP concept, applying biologically compatible quantum dots (QDs), was created for can…
ISEF · 2014
Mathematics
Problem: Primary care of external bleeding is extremely important, providing basic care of any wound that is crucial in life saving and preventing future morbidity. Bleeding is a main conseq…
ISEF · 2014
Mathematics Fourth Award
Short non-coding RNAs, microRNAs (miRNAs) regulate gene expression by silencing their target mRNAs through degradation. Because miRNA dysregulation is linked with tumorigenesis, expression s…
ISEF · 2014
Mathematics
The current study investigated the effectiveness of UV protection strategies – avobenzone based sunscreen (A), zinc oxide based sunscreen (Z), untreated cloth, SunGuard™ treated cloth UV pro…
ISEF · 2014
Mathematics
The higher incidence of DCIS cases in underdeveloped nations and an increased need for cytopathological tests have placed an undue learning burden on the medical enterprise to process millio…
ISEF · 2014
Mathematics Third Award
Multidrug resistance (MDR) is a major obstacle to successful chemotherapy. The main cause of MDR is the increased drug efflux by ABC transporters. AC220 is a potent and selective inhibitor o…
ISEF · 2014
Mathematics Third Award
Although the failure of single-targeted chemotherapy agents is inevitable, recent studies demonstrate that combinatorial dual therapy can effectively treat most cancers. However, two major o…
ISEF · 2014
Mathematics
One in every 3,500 newborns is diagnosed with Neurofibromatosis 1 (NF1), a common genetic disorder. Many NF1 patients develop painful tumors along their peripheral nervous system. The NF1 di…
ISEF · 2014
Mathematics
Many doctors often recommend “a glass of wine at night” to many patients to resolve blood-sugar issues, increase immune system strength, and promote cardiovascular health. It has been found…
ISEF · 2014
Mathematics Third Award
Despite high responses to current therapeutic methods, about 90% of ovarian cancer patients develop recurrence. The inability to efficiently combat metastasis makes ovarian cancer lethal as…
ISEF · 2014
Mathematics
Using the Kirby Bauer Protocol, my recent findings show silver ions can override antibiotic resistance in E. coli. Control trials were cultured E. coli on Mueller-Hinton agar with the additi…
ISEF · 2014
Mathematics
The ankle-foot complex is a joint mechanism that can provide stability, bear heavy weight loads, and provide fluid movement. Improper alignment of the foot affects the ankle and subsequently…
ISEF · 2014
Mathematics
Glucose (sugar) is the fuel of the body, but does it actually result in better performance? I tested the mental and physical responses to glucose. My hypothesis was that there would be a sug…
ISEF · 2014
Mathematics
Taste sensitivity, known to be genetically inherited, varies greatly in individuals and has been shown to strongly influence food choices. There are normal tasters, non-tasters, recessive an…
ISEF · 2014
Mathematics
Antibiotic resistance is a significant problem in contemporary medicine. Drug-resistant microbial strains limit the number of treatments available to patients, which has led to a push for ne…
ISEF · 2014
Mathematics
Currently breast cancer and complications for Diabetes are the two major public health problems in Latin America. It is estmated that onde of every ten women and one in every hundred men hav…
ISEF · 2014
Mathematics
The purpose of this experiment was to test the accuracy of blood pressure, heart rate, blood oxygen levels, and eye dilations in order to determine a more accurate way to determine if somebo…
ISEF · 2014
Mathematics
Triclosan is an antibacterial and antifungal agent used in commercial goods since 1972, and is now found in a wide variety of household items and personal care products (PCPs). Factors inclu…
ISEF · 2014
Mathematics
Steptococcus mutans and Aggregatibacter actinomycetemcomitans (AA) are bacterial strains commonly found in the dental plaque biofilm and which cause conditions such as dental caries, gingivi…
ISEF · 2014
Mathematics First Award
Antibiotic resistance is an ever growing threat. Bacterial infections resistant to carbapenems, a “last resort” antibiotic, have been sharply rising and can cause “potentially untreatable in…
ISEF · 2014
Mathematics
A previous study demonstrated that 5.5 % of the Saudi population have Coronary Artery Disease- CAD. Plavix (Clopidogrel) is the preventative measure of choice and is a prodrug antiplatelet a…
ISEF · 2014
Mathematics
The human brain has the ability to regenerate, remodel, and form new neural connections. This process, known as neuroplasticity, is regulated by the neurotrophin Brain-Derived Neurotrophic F…
ISEF · 2014
Mathematics
The purpose of this experiment was to determine which antibiotic was the most effective at killing and inhibiting both gram positive and gram negative bacteria. This is an interesting questi…