Biochemistry
BRCA1 is a tumor suppressor protein essential for DNA repair, cell cycle regulation, and the maintenance of genomic stability. Mutations in the BRCA1 gene are strongly associated with an inc…
Chemistry
Arsenic contamination in groundwater affects over 200 million people globally. Inorganic arsenic, mainly arsenite (As(III)) and arsenate (As(V)), is classified as a Group 1 human carcinogen,…
Chemistry
Synthetically created superabsorbent polymers (SAPs) are used in everyday items like diapers, bandages, and feminine hygiene products. These SAPs are not biodegradable, and the production pr…
Chemistry
Objective: Acetaminophen (APAP) should ideally be absorbed in the small intestine, but up to 15% of the drug is released in the stomach, resulting in suboptimal delivery. This study evaluate…
Chemistry
Biological molecules, such as DNA and RNA have a variety of pharmaceutical and medical applications and were heavily utilized within the creation of the Covid-19 vaccine. However, biological…
Biochemistry
Silk fibroin is a sustainable biopolymer with extraordinary mechanical properties derived from its hierarchical self-assembly into ß-sheet nanostructures. Biological silk spinning leverages…
Biochemistry
Ionizable lipid nanoparticles (LNPs) are the mainstream delivery mechanisms for mRNA vaccines, with their pH-sensitive protonation facilitating post-endocytic endosomal escape. However, LNPs…
Chemistry
Acute kidney injury (AKI) affects over 13.3 million people annually, yet early diagnosis remains difficult because renal damage often develops subclinically before overt dysfunction becomes…
Chemistry
This project investigates Liesegang-type self-organization phenomena for the development of functional biomaterials for bone regeneration and controlled drug delivery. The experimental proce…
Chemistry
The purpose of this experiment was to test the spread and droplet size of a drone application with and without a chemical surfactant adjuvant. It is hypothesized, the water with the chemical…
Chemistry
This study was aimed at examining the effects of metal ions on the classical ninhydrin reaction. During the process, a surface-bound species was incidentally discovered, and its structure an…
Chemistry
This project investigates the multi-spectroscopic characterization of Cobalt(II) meso-Tetra(4-sulfonatophenyl)Porphine (CoTPPS) and its metal-free counterpart, TPPS, under varying concentrat…
Chemistry
N-heterocyclic carbenes (NHCs) have emerged as excellent spectator ligands in homogeneous catalysis, especially in transfer hydrogenation reactions. Transfer hydrogenation, the reduction of…
Chemistry
Antimicrobial peptides (AMPs) are promising alternatives to conventional antibiotics due to their membrane-disruptive activity, but clinical translation is hindered by host cytotoxicity, poo…
Chemistry
Termites, among the most destructive insects, cause nearly US$50 billion in worldwide economic losses annually. For decades, the use of synthetic insecticides such as fipronil has proven hig…
Biochemistry
Hypermobile Ehlers Danlos Syndrome (hEDS) is a connective tissue and joint disorder that millions of people are affected with. Patients affected suffer from chronic pain and increased risk o…
Chemistry
Aryl Bromides are significant compounds having great potential in cross-coupling reactions and interconversions of functional groups. To functionalize these groups into boronates (high-value…
Biochemistry
The main goal of the project is to develop a functional, inexpensive and easily reproducible method for testing the interactions of gastrointestinal glycoproteins, mucins, with a wide range…
Biochemistry
Glioblastoma (GBM) is the most aggressive primary brain tumor. It is associated with poor survival and frequent development of resistance to the first-line chemotherapeutic agent temozolomid…
Biochemistry
Acid-sensing ion channels (ASICs) are proton-gated, voltage-insensitive transmembrane proteins activated in acidic conditions, playing crucial roles in neuronal signaling. ASIC subunit 1a is…
Chemistry
This study was performed to investigate the efficiency of different methods to extract lignin, which is used for many different purposes in industry. Six types of wood were used. All types o…
Chemistry
Ammonia fertilizers feed over half of the global population. However, its synthesis through the Haber-Bosch process is extremely unsustainable, leading to over 20% of global chemical CO2 emi…
Biochemistry
Hair health is an important factor in maintaining a healthy body. Although hair appears strong, it is constantly exposed to mechanical wear, environmental factors, heat, chemical treatments,…
Chemistry
Traditional silicon solar cells are limited to approximately 33% efficiency, proposed by the Shockley-Queisser limit. Singlet fission (SF), a process in which one singlet exciton splits into…
Chemistry
Humic acid supplements are marketed as natural detoxifiers that claim to bind harmful metals while leaving essential metals unaffected. This study evaluated the selective binding of copper a…
Biochemistry
Obesity has increased to 1 in 8 people globally, causing dangerous comorbidities, including type 2 diabetes, cardiovascular disease, and cancer. Many obese adults, particularly in low socio-…
Chemistry
Aromatic amino acids phenylalanine (Phe), tryptophan (Trp), and tyrosine (Tyr) show increased plasma concentrations in cases of phenylketonuria, tryptophanemia, and tyrosinemia type I that o…
Biochemistry
Around the world, 15% of adolescents struggle with mental illnesses affecting mood and behavior. Depression, one of the most common conditions, is diagnosed primarily through clinical evalua…
Chemistry
Current organic photovoltaics (OPV) have narrow light absorbance, inefficient electron transport, and low energy output. This project aims to solve these efficiency issues by designing an or…
Chemistry
In recent years, functional nanostructured materials with high catalytic stability, low cost, and tunable catalytic properties have become excellent alternatives to natural enzymes used as b…