20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2019
Biomedical and Health Sciences
With an ~70% fatality rate, ovarian cancer is classified as the deadliest gynecological malignancy. Recent gene therapy using p53 failed. An alternative approach to wild type (wt) p53 is mit…
ISEF · 2019
Translational Medical Science
The prolonged exposure to UV rays emitted by the sun, has generated various diseases that affect human health, such as: skin burns, premature photoaging and it can worsen skin cancer. These…
ISEF · 2019
Biomedical and Health Sciences
Increased telomerase activity and sustained telomeres are hallmarks of non-small cell lung cancer (NSCLC) and encourage cancer growth by inhibiting cellular apoptosis. This study analyzes Pi…
ISEF · 2019
Biomedical and Health Sciences Third Award
Hypodiploid B-cell acute lymphoblastic leukemia (B-ALL) is a high-risk form of acute leukemia with a dismal prognosis. Because standard chemotherapy is largely ineffective for this subtype,…
ISEF · 2019
Translational Medical Science Third Award
Nanoparticle research is an emerging field of medicine meant to tackle cancer using diverse constructs; however, nanoparticles suffer from improper and insufficient delivery, which has led t…
ISEF · 2019
Translational Medical Science
Do healthy and cancer cells differ in temperature? Can this be explained by different metabolisms? These questions arose during the search for a non-invasive diagnostic method for breast can…
ISEF · 2019
Biomedical and Health Sciences
African American (AA) men are disproportionately affected by prostate cancer (PCa), with almost twice the incidence and mortality as compared to non-Hispanic Whites. AA have been left out of…
ISEF · 2019
Biomedical and Health Sciences
The Ptychosperma macarthurii, commonly known as the MacArthur Palm, is an underutilized palm. Ethanolic extracts were made from the palm’s seeds collected from fruits were tested on HeLa Cer…
ISEF · 2019
Translational Medical Science
According to the World Health Organization, air quality is considered one of the greatest sanitary challenges related to respiratory and cardiovascular diseases such as asthma, pulmonary can…
ISEF · 2019
Translational Medical Science
Ewing’s sarcoma (EWS) is a highly aggressive type of cancer that primarily occurs in children and young adults. Doxorubicin (DOX) is a commonly used anti-cancer drug for the treatment of EWS…
ISEF · 2019
Biomedical and Health Sciences
Hypertrophic cardiomyopathy (HCM) is a cardiovascular disease that triggers sudden cardiac arrest in people of all ages. We conducted tests with six chemotherapy drugs that reinforced separa…
ISEF · 2019
Biomedical and Health Sciences
The purpose of this project is to study how the Toll-like receptor 8 (TLR8) pathway prevents tumor-induced T cell suppression. Tumor-induced immunosuppression is important to study because i…
ISEF · 2019
Biomedical and Health Sciences
Being the second most common cancer in both men and women, and having an average 5-year survival rate of only 17.7%, lung cancer is a high-incidence disease with low survival. The currently…
ISEF · 2019
Translational Medical Science
This study will evaluate the efficacy of the herbal supplement Withania somnifera (Ashwagandha root) for treatment of depression, anxiety and stress. The American Psychological Association s…
ISEF · 2019
Translational Medical Science
The purpose of this project was to produce a mobile application which is accessible to the whole population. The application will detect certain measurements in the eye: pupil center and siz…
ISEF · 2019
Translational Medical Science
In the U.S., over 20 million cases of healthcare associated infections (HAIs) are reported, contributing to $3 trillion in healthcare costs and 5.9 million tons of waste annually. HAIs are c…
ISEF · 2019
Biomedical and Health Sciences
Myocardial fibrosis is a significant global health problem associated with nearly all forms of heart disease. It is primarily caused by hypertrophic scarring of the heart’s ECM through patho…
ISEF · 2019
Translational Medical Science
Tumor-mediated immunosuppression allows tumors to hide from the immune system and avoid recognition. One way of reversing this suppressive microenvironment is to activate antigen-presenting…
ISEF · 2019
Biomedical and Health Sciences
Effects of Sleep Deprivation and Herb Medication Ganwei on Behavioral and Biochemical Responses in Drosophila Alzheimer’s Disease Model Alzheimer’s Disease: Sleep Deprivation and Herb Therap…
ISEF · 2019
Biomedical and Health Sciences
Hematopoietic stem cell (HSC) transplant failure can be attributed to graft failure, poor graft function, and the failure of the homing process in which the transplanted cells settle into th…
ISEF · 2019
Biomedical and Health Sciences
BACKGROUND: Hypertension is still considered a major global public health concern. Unlike previous classification, the new ACC/AHA (2017) categorized 130-139/80-89 mmHg as stage 1 hypertensi…
ISEF · 2019
Biomedical and Health Sciences
In recent years, the popularity of the Juul e-cigarette, and products similar to it, have increased dramatically, with Juul now leading the e-cigarette market. They are especially prevalent…
ISEF · 2019
Translational Medical Science
In Vietnam, many patients with chronic renal failure requires high cost for treatment. Aims: Finding the scientific basis for developing new drug from Vietnamese medicinal herbs to prevent a…
ISEF · 2019
Biomedical and Health Sciences
Sulforaphane (SFN) is a compound within the isothiocyanate group of organosulfur compounds and found in cruciferous vegetables, such as broccoli, Brussels sprouts, and cabbages. Many health…
ISEF · 2019
Translational Medical Science
The prescription opioid epidemic in the United States resulted in an astounding 49,068 deaths in 2017 alone (NIH), warranting URGENT attention. Besides the required policy changes, innovativ…
ISEF · 2019
Translational Medical Science
Tender Coconut Water (TCW), the liquid endosperm of young coconut fruit is not only rich in nutrients but also has bioactive phytohormones such as zeatin, kinetin and their derivatives. Prev…
ISEF · 2019
Biomedical and Health Sciences
Cancer is one of the main causes of morbidity and mortality in the world. Among the types of cancer, ovarian cancer has the lowest prospect of survival of all female cancers, with survival r…
ISEF · 2019
Biomedical and Health Sciences Fourth Award
Lactose intolerance is a common digestive system disorder caused by an inability to break down lactose, the common sugar in milk and dairy products. There is currently no long-term treatment…
ISEF · 2019
Biomedical and Health Sciences Fourth Award
Epilepsy is a neurological disorder affecting a significant percentage of the human population. It is characterized by seizures that occur when neurotransmitter inhibition fails. One well-id…
ISEF · 2019
Biomedical and Health Sciences
A one-month, randomized parallel clinical trial was used to determine the effect of a low-carbohydrate diet on cardiovascular disease risk factors: BMI, body weight, and triglycerides. Parti…