Translational Medical Science
The hypothesis of the project was that machine learning can be used to identify disease patterns in medical imaging. Machine learning functions were used to identify patterns in chest X-rays…
Translational Medical Science
Thousands of people are affected by ovarian cancer each year. Usually, ovarian cancer is not detected in the early stages. Typically, the cancer is detected when a tumor is already formed. T…
Biomedical and Health Sciences
Colon cancer is a leading cause of death worldwide. Sea cucumbers are a potential source of medicinal compounds and have been consumed in traditional Chinese medicine. Thus, it was hypothesi…
Translational Medical Science
The purpose of this experiment is to identify the effects of different 2 Deoxy-D-glucose (2DG) concentrations on the proliferation of cancer cells. It was hypothesized that if a 2DG concentr…
Biomedical and Health Sciences
Planarian, more specifically Brown planarian have an extremely high concentration of neoblast stem cells and causes the planarian to have some of the most reliable regeneration powers. This…
Biomedical and Health Sciences
Obesity has reached epidemic proportions, becoming a preventable leading cause of death worldwide. A multitude of approaches and animal models have been employed to investigate the pathophys…
Biomedical and Health Sciences
Surgical fires pose a major threat in the operating room (OR) to patients, personal, and to facility. Surgical Drapes served fuel for 85% of fires and 81% of fires involve electrocautery, wi…
Biomedical and Health Sciences (inferred)
Glioblastomas (GBM) are the most common primary malignant brain tumor in adults and are recognized as one of the deadliest forms of cancer. Despite aggressive therapy consisting of maximal s…
Translational Medical Science
A significant number of cases of Salmonellosis have been linked to the handling of the more than 50 million day old chicks sold annually from mail order hatcheries, suggesting the need for i…
Biomedical and Health Sciences
Lupus Nephritis (LN) is an autoimmune disease that leads to chronic inflammation of the kidney and excessive proteinuria. Current methods of treatment involve management of symptoms and slow…
Biomedical and Health Sciences (inferred)
Tumor mediated immunosuppression allows tumors to hide from the immune system and avoid recognition. One way of reversing this suppressive microenvironment is to activate antigen-presenting…
Biomedical and Health Sciences
Traumatic brain injury (TBI) affects about 1.7 million individuals annually. It is one of the leading causes of death and disability in the U.S. The Klotho gene, which plays an important rol…
Translational Medical Science
Breast cancer is the second leading cause of cancer mortality in women, contributing to roughly 40,000 deaths annually. While breast cancer can pose a threat to any woman, those with dense b…
Translational Medical Science
Antibiotics are powerful medicines that fight certain infections and can save lives when used properly. However, with bacteria becoming more resistant to antibiotics, new methods to treat ba…
Translational Medical Science
Experimentation was conducted to determine the presence of metabolic deviations as a result of nucleosome-remodeling factor (NURF) knockdown in combination with chemotherapies. Due to large…
Biomedical and Health Sciences
Anxiety is the most common mental disorder in the United States, affecting some 40 million adults each year. During anxiety attacks, neurons release excessive amounts of adrenaline, causing…
Translational Medical Science
Cancer has remained as one of the world's leading causes of death and although medical treatments exist, many of the current methods have cytotoxic effects to not only the cancer cells, but…
Biomedical and Health Sciences
The survival rate for patients diagnosed with gliomas (the most common type of brain tumor) is 5.6%. Gliomas are primarily driven by pathways like NF-kB signaling, which plays a key role in…
Biomedical and Health Sciences
Rheumatoid Arthritis is a debilitating autoimmune disease in which the body— a person’s immune system— attacks its own synovium. Rheumatoid arthritis results in heightened inflammatory respo…
Translational Medical Science
Ivermectin, awarded the Nobel Peace Prize for Physiology or Medicine in 2015, was originally used as an anthelmintic. Ivermectin was invented by William Campbell and Satoshi Omura to treat p…
Translational Medical Science
Research shows that mammograms can be 80-90 percent accurate in detecting breast cancer in women without dense tissue, however the accuracy of this metric drops drastically down to nearly 50…
Translational Medical Science
Millions of people worldwide suffer from chronic pain with few treatments other than opioids available. Photobiomodulation (PBM) and electroacupuncture (EA) are two treatments for chronic pa…
Biomedical and Health Sciences
Introduction: Children with mutations in mannose phosphate isomerase (MPI) develop early liver fibrosis that can progress to require liver transplantation. We have previously shown that MPI…
Biomedical and Health Sciences
The K27M mutation in histone H3.3 drives incurable glioblastomas in children called Diffuse Intrinsic Pontine Gliomas (DIPG). Research in human cells shows that a deficiency in H3.3 protein…
Biomedical and Health Sciences
Coronary Artery Disease (CAD) is one of the leading causes of death worldwide, accounting for 31% of all deaths globally in 2016. This work will investigate the possibility of detecting CAD…
Biomedical and Health Sciences (inferred)
Major depressive disorder (MDD) is a common mental disorder that affects adolescents and adults, causing staggering economic burdens, disabilities in the workforce, and suicidal thoughts, if…
Translational Medical Science
Hepatoblastoma is the most common liver tumor in children. Those with relapsed or metastatic disease continue to have a poor prognosis and require novel therapies to improve outcomes. PIM ki…
Biomedical and Health Sciences
Right ventricular (RV) dysfunction is the main determinant of mortality in patients with pulmonary arterial hypertension (PAH); yet, there is limited information on the role of RV inflammati…
Translational Medical Science
The aim of our work was to create an affordable and easy-to-use device for the early diagnosis of transparency disorders in the optical media of the human eye. As a result of the analysis of…
Translational Medical Science
Pancreatic cancer (PC) is the fourth leading cause of cancer death in the United States because it’s five-year survival rate is 8.9%. This occurs because of late diagnosis which is affiliate…