20,037 real projects from ISEF, the Canada-Wide Science Fair, JSHS and the Calgary Youth Science Fair — searchable by meaning, and filterable by fair, year, category and award.
ISEF · 2023
Translational Medical Science Fourth Award
Liver cancer is the third leading cause of cancer deaths worldwide, resulting in over 800,000 deaths each year. About 90% of all primary liver cancers are characterized as hepatocellular car…
ISEF · 2023
Biomedical and Health Sciences
Osteoarthritis (OA) is the most common joint disease, with over 527 million patients worldwide reported in 2019. The diagnosis of OA is mainly based on clinical findings and imaging studies.…
ISEF · 2023
Translational Medical Science
Alzheimer’s Disease (AD) is a progressive, neurodegenerative disease that leads to brain atrophy and neuronal apoptosis and is the leading cause of dementia worldwide. Minimal insight has be…
ISEF · 2023
Biomedical and Health Sciences
A systematic review of the research literature addressing risk factors for ALS was completed for the years 2011 to 2022. The strongest research articles were then reviewed for the highest po…
ISEF · 2023
Translational Medical Science Third Award
Autism Spectrum Disorder is one of the leading neurodevelopmental disorders in our world, present in over 1% of the population and rapidly increasing in prevalence, yet the condition lacks a…
ISEF · 2023
Biomedical and Health Sciences Fourth Award
Lithium, the first-line treatment for bipolar disorder (BD), reportedly causes chronic kidney disease (CKD) in at least 20% of patients. To manage BD, physicians prescribe lithium carbonate…
ISEF · 2023
Translational Medical Science Fourth Award
Alzheimer’s disease (AD) is a progressive neurodegenerative disease that impacts memory by destroying the neurons of the brain cells. AD is characterized by the presence of two types of prot…
ISEF · 2023
Translational Medical Science
Melanoma is a rapidly metastasizing deadly cancer making it crucial to find the most effective treatment immediately. This year in the US, it is expected to be diagnosed in 97,610 patients a…
ISEF · 2023
Translational Medical Science Fourth Award
Neuroblastoma is one of the most severe tumors in young children with nearly 500 new cases reported each year. Currently, the only treatments available for this cancer are chemotherapy and r…
ISEF · 2023
Biomedical and Health Sciences
Endometrial cancer is the 4th commonest cancer in women. The current treatment options show inconsistent results. There is a newer treatment option called targeted therapy. One example uses…
ISEF · 2023
Biomedical and Health Sciences Third Award
The rising cases of children with autism spectrum disorders (ASD), having restrictive repetitive and impaired social behaviors, can be linked to maternal factors during fetal development. Ad…
ISEF · 2023
Translational Medical Science
Glioblastoma (GBM), the most malignant brain tumor, remains nearly universally fatal despite aggressive cancer treatment involving surgery, radiation and temozolomide (TMZ) chemotherapy. TMZ…
ISEF · 2023
Biomedical and Health Sciences
The research and development of new medicine are expensive and time-consuming: the entire process from discovery to distribution takes up to 12 years, costing as much as $2.5 billion USD. Hu…
ISEF · 2023
Translational Medical Science
The development of therapeutic antibodies with high binding affinities is essential for various in vivo applications, including passive immunization, antigen-presence diagnostics, and cancer…
ISEF · 2023
Biomedical and Health Sciences
Autism spectrum disorder (ASD) is characterized by difficulties in processing sensorimotor information and general cortical excitability. Symptoms are likely attributable to impairments in c…
ISEF · 2023
Translational Medical Science
In multiple sclerosis (MS), existing diagnostic tools, including clinical magnetic resonance imaging (MRI) and neurological status scales, do not reliably represent disease severity or progr…
ISEF · 2023
Biomedical and Health Sciences
Recent research on the drug famotidine suggests it may be an affordable, accessible, safe, and effective treatment against COVID-19. Famotidine is a histamine 2 receptor (H2R) antagonist tha…
ISEF · 2023
Translational Medical Science
This study aimed to determine whether traumatic brain injury (TBI) causes learning and short-term memory (STM) deficits in Drosophila melanogaster, and if THIP, a GABA-A receptor agonist, wi…
ISEF · 2023
Translational Medical Science
Vinblastine is a cytotoxic drug that has been proven to stunt the growth of cancer cells by binding to the mitotic spindle during anaphase. Studies have shown that Alpha Tocopheryl, a type o…
ISEF · 2023
Biomedical and Health Sciences
Although stem cell transplants have made promising clinical progress as a treatment for leukemia and other blood cancers, their safety and the severe complications they pose have significant…
ISEF · 2023
Biomedical and Health Sciences
Myocardial infarction (MI), or heart attack, is the death of cardiac tissue to improper blood and oxygen flow. MI is a form of cardiovascular disease, the current leading cause of death, acc…
ISEF · 2023
Biomedical and Health Sciences Fourth Award
Type two Diabetes is an epidemic. Because there is no cure for diabetes and the current treatments can be expensive and inaccessible, exploration for more affordable management tools for the…
ISEF · 2023
Translational Medical Science Fourth Award
G-quadruplex structures (G4s) are one of many secondary structures that genomic DNA adopts, apart from its canonical B-form, and they are a vital part of cellular regulation. Sequences that…
ISEF · 2023
Translational Medical Science Third Award
Small cell lung cancer (SCLC) is an extremely aggressive form of lung cancer with a less than 5% five-year survival rate. The poor prognosis is mainly attributed to the lack of effective, lo…
ISEF · 2023
Translational Medical Science
Ginkgo biloba is an essential herbal agent that is effective on nerve cells and may have therapeutic or preventive effects with its water-soluble bioactive components. In our study, we worke…
ISEF · 2023
Translational Medical Science
I chose this project because the world around us is filled with information about products and substances. With the push of Vape sticks and alternatives like CBD, and the consequent sanction…
ISEF · 2023
Translational Medical Science
With just 5% survival rates, Liver cancer is one of the deadliest cancers in the world. Due to its low survival rates, early diagnosis of liver disease is extremely crucial. The aim of the p…
ISEF · 2023
Translational Medical Science
One of the most important metrics of cardiac health is ejection fraction. EF is the percentage of blood pumped out of the left ventricle each time the heart contracts and is most commonly an…
ISEF · 2023
Biomedical and Health Sciences
My research this year continued to investigate the anticancer effects of Lomatium dissectum, commonly known as fern leaf biscuit root (“doza" in our Native language), and Sambucus caerulea,…
ISEF · 2023
Biomedical and Health Sciences
The purpose of my research was to investigate the possible antibacterial properties of Artemisia tridentata (Big Sagebrush). I hypothesized that Artemisia tridentata would inhibit the growth…