Browse real student projects, abstracts, and awards.
ISEF · 2025
Biomedical and Health Sciences
Age-related macular degeneration, or AMD, is a progressive degeneration of the retina that causes significant central visual impairment, impacting nearly 20 million elderly adults in the Uni…
ISEF · 2025
Biomedical and Health Sciences
Duchenne Muscular Dystrophy (DMD) is a severe genetic condition that causes progressive muscle weakness and degeneration. Despite current treatments focusing on symptom management, no cure e…
ISEF · 2025
Translational Medical Science
Despite the fact that studies have established a notable link between tourism-particularly cruise ship traffic-and increased respiratory illnesses, there is a lack of official research exami…
ISEF · 2025
Translational Medical Science
Thyroid cancer (TC) is one of the most common endocrine malignancies worldwide, with 821,214 newly diagnosed cases in 2022. It has the fastest growth rate across all cancers. Despite its pre…
ISEF · 2025
Biomedical and Health Sciences
Congenital heart defects (CHDs) refer to structural defects in the heart that are present at birth. Hypoplastic Left Heart Syndrome (HLHS) is the most complex CHD and occurs when the left si…
ISEF · 2025
Translational Medical Science
Rheumatoid Arthritis (RA) is an autoimmune arthropathy that affects over 18 million people globally, causing immense joint pain and swelling. Current treatments (e.g., methotrexate, adalimum…
ISEF · 2025
Biomedical and Health Sciences
Inflammation is the body's natural response to combat infections, allergies, or injuries. The most commonly available treatments—non-steroidal anti-inflammatory drugs (NSAIDs) and corticoste…
ISEF · 2025
Translational Medical Science
Commonly known as the yellow water lily root or kaandoosh in Ojibwe language, the rhizome of Nuphar advena is utilized by Indigenous communities for treating a wide variety of ailments, incl…
ISEF · 2025
Translational Medical Science
Stroke, the fifth leading cause of death and a major cause of disability in the US, is a time-critical emergency handled by EMS agencies—20% of which manage 80% of service calls (Krohmer & E…
ISEF · 2025
Translational Medical Science
Diabetic macular edema (DME) is a leading cause of vision impairment, affecting up to 30% of diabetics. It results from retinal fluid buildup due to vascular leakage and is commonly treated…
ISEF · 2025
Biomedical and Health Sciences
Duchenne Muscular Dystrophy (DMD) is an inherited X-linked disease with an incidence of 1:3,600. Patients become weak at 2-3 years old with progression to respiratory failure and death in th…
ISEF · 2025
Biomedical and Health Sciences
Colorectal cancer (CRC) is the third most common cancer globally, with over 1.9 million new cases and nearly 1 million deaths annually. The incidence of early-onset CRC, defined as cancer oc…
ISEF · 2025
Biomedical and Health Sciences
Immune checkpoint inhibitors (ICIs) have emerged as a promising therapy for late-stage lung cancer. However, the response rate to ICIs remains low. As a result, there is a need to better und…
ISEF · 2025
Translational Medical Science
Metabolic disorders and malnutrition remain critical health concerns, often undiagnosed due to invasive, costly, and inaccessible testing methods. VitalEdge is a novel non-invasive biosensor…
ISEF · 2025
Translational Medical Science
Wound care management is a major medical challenge, causing significant clinical, social, and economic burden. To address this, I developed WoundView, an AI-powered app for real-time wound a…
ISEF · 2024
Translational Medical Science
Alzheimer's disease is a neurodegenerative disorder that affects more than 50 million people worldwide. Current diagnostic methods include cerebrospinal fluid testing, which is invasive and…
ISEF · 2024
Biomedical and Health Sciences
Mammography, currently the primary method implemented for breast cancer screening/detection, often produces false negatives (1 in 8). Additionally, there exist prolonged delays during diagno…
ISEF · 2024
Biomedical and Health Sciences
Accurately identifying the relationship between regulators and disease has long been a challenge in the field of biomedical research due to its crucial roles in pathobiological conditions. M…
ISEF · 2024
Translational Medical Science Second Award
Elderly populations are at an increasing risk of dementia, and accessibility to status-quo diagnosis tools is a significant issue, as proposed by the substantial rates of undiagnosed cases.…
ISEF · 2024
Translational Medical Science
Diabetic retinopathy (DR), a primary cause of vision loss worldwide, is projected to affect 130 million individuals by 2030. Difficulties related to diagnosis have led to an estimated underd…
ISEF · 2024
Translational Medical Science First Award
Renal Cell Carcinoma (RCC) is the world's deadliest urological disease. Although detection before metastasis can raise a patient's 5-year survival rate by over 75%, current diagnostic method…
ISEF · 2024
Translational Medical Science Fourth Award
Wound care is an essential part of patient healthcare. However, infections worldwide are increasing at a record rate due to disease, microbes, and antibiotic resistance. Unfortunately, preve…
ISEF · 2024
Translational Medical Science
Diabetic retinopathy (DR), a prevalent complication of diabetes, poses a significant threat to vision health, particularly in resource-limited rural settings. In 2023, a regional study in Al…
ISEF · 2024
Translational Medical Science Fourth Award
Arsenic is toxic. The primary goal of this research is to scientifically detect and quantify arsenic levels in drinking water due to local residents’ concerns and assess the potential health…
ISEF · 2024
Translational Medical Science Third Award
Microglial cells have the ability to engulf HIV-1 infected glial cells by binding to neuronal blebs, effectively stopping the subsequent encephalopathy. However, two HIV-1 accessory proteins…
ISEF · 2024
Translational Medical Science Third Award
The precise and accurate leukemia detection in current clinical practice remains challenging due to limitations in cost, time, and medical experience. To address this issue, this research de…
ISEF · 2024
Translational Medical Science
Ocular melanoma is one of the rarer types of aggressive cancer. The only option for someone with this cancer is to undergo radiation or surgery. In both cases, there is a high likelihood of…
ISEF · 2024
Translational Medical Science
Alzheimer's Disease is one of the leading causes of death of adults in the USA. The primary hallmarks of Alzheimer's are Amyloid-Beta plaques and Tau-Aggregation, known for causing inflammat…
ISEF · 2024
Biomedical and Health Sciences
Polycystic Ovary Syndrome (PCOS) is an endocrine disorder characterized by hormonal imbalance due to excessive levels of androgens and affects approximately 10% of women. Caenorhabditis eleg…
ISEF · 2024
Translational Medical Science
The objective of this study was to investigate the effect of Metformin, the effect of Y15, and the combinational effect of Y15 and Metformin for the treatment of platinum-resistant ovarian c…