Browse real student projects, abstracts, and awards.
ISEF · 2025
Biomedical and Health Sciences
Energy drinks are very popular; however, excessive consumption has been linked to various health risks, including anxiety, dehydration, and cardiovascular complications. This study aimed to…
ISEF · 2025
Biomedical and Health Sciences
Liposarcoma (LPS) is a form of cancer derived from fat tissue. Despite the fact that the 5 year survival rate for LPS patients with metastasis is only 15%, treatment for LPS hasn’t been adva…
ISEF · 2025
Biomedical and Health Sciences
Preliminary data shows that cigarette smoke is associated with gene expression changes in whole blood and skin. However, little is known about the epigenetic and genetic response to smoking…
ISEF · 2025
Biomedical and Health Sciences
The Body Mass Index carries gender and ethnic bias that will endanger the future of AI diagnosis. The BMI overlooks that people can have the same BMI yet have vastly different body compositi…
ISEF · 2025
Biomedical and Health Sciences
Intracranial aneurysms (IAs) are a vascular disorder characterized by the bulging of weakened cerebral blood vessel walls. Affecting 166 million people globally, IAs pose a serious risk due…
ISEF · 2025
Biomedical and Health Sciences
As global energy needs have skyrocketed in the past decade, energy byproduct has increased in tandem. Places like Mooresville, North Carolina; Pineville, Indiana; and southeastern Puerto Ric…
ISEF · 2025
Biomedical and Health Sciences
Parkinson’s disease (PD) is a common neurodegenerative disease (NDD) that is characterized by the gradual loss of dopaminergic neurons and progressive motor impairment. Recent studies sugges…
ISEF · 2025
Translational Medical Science
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor prognosis, signifying a pressing need for novel therapeutic strategies. This study investigated the effect of…
ISEF · 2025
Biomedical and Health Sciences
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the progressive degeneration of motor neurons, leading to muscle weakness, paralysis, and ultimatel…
ISEF · 2025
Translational Medical Science
Lung cancer remains the as the leading cause of cancer-related deaths worldwide, with an estimated 124,730 deaths in the United States alone in 2025. The situation in Hawai?i is especially c…
ISEF · 2025
Biomedical and Health Sciences
Diabetes is one of the most actual issues in today's world. 90% of 800 million diabetics have type 2 diabetes. In our experiment, we studied the Galega Officinnalis plant, which is used in t…
ISEF · 2025
Biomedical and Health Sciences
Early diagnosis of neurodevelopmental disorders (NDDs) such as Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) enables early intervention and is crucial fo…
ISEF · 2025
Translational Medical Science
The use of therapeutic siRNA to silence genes in a sequence-specific manner has been limited by its need for delivery to target cells. However, while antibody-mediated siRNA delivery shows p…
ISEF · 2025
Biomedical and Health Sciences
Late-stage keratoconus is a progressive corneal disease causing severe visual loss. Conventional treatments, like corneal rings, often fail in advanced cases due to insufficient tensile stre…
ISEF · 2025
Translational Medical Science
95% of chronic kidney disease (CKD) patients miss early detection, mostly diagnosed at late stages, contributing to an annual mortality of 11 million globally. Current screening methods, suc…
ISEF · 2025
Translational Medical Science
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world, affecting 20 million in the US alone. Retinal Pigment Epithelial (RPE) cells between the reti…
ISEF · 2025
Biomedical and Health Sciences
Pancreatic cancer is the second leading cause of death, with 90% of occurrences as Pancreatic ductal adenocarcinoma (PDAC). Currently, Doxorubicin (DOX) is the leading treatment for cancers.…
ISEF · 2025
Translational Medical Science
Purpose: Patients with breast cancer (BC) who undergo neoadjuvant therapy (NAT) before surgery and achieve a pathologic complete response (pCR) after NAT have a low rate of recurrence. Howev…
ISEF · 2025
Translational Medical Science
Each year, 1.9 million people worldwide are diagnosed with colorectal cancer, and early detection of cancerous polyps is crucial for treatment. Endoscopic imaging is a critical part of ident…
ISEF · 2025
Translational Medical Science
In 2024 the American Cancer Society (ACS) reported a 78% death rate for pancreatic cancer. The 5-year survival rate for pancreatic cancer is 13%. ACS states the only effective method known t…
ISEF · 2025
Biomedical and Health Sciences
Leigh Syndrome (LS) is a rare mitochondrial disorder caused by mutations in the SURF1 gene, leading to reduced Complex IV enzymatic activity, impaired oxidative phosphorylation, and severe m…
ISEF · 2025
Biomedical and Health Sciences
Glioblastoma (GBM) is the most predominant malignant brain cancer in adults without prognosis improvement in decades. Nevertheless, 83% of GBM cases have Telomerase Reverse Transcriptase pro…
ISEF · 2025
Translational Medical Science
Recent advancements in extended reality (XR), encompassing augmented reality (AR), virtual reality (VR), and mixed reality (MR), have demonstrated significant potential in transforming the m…
ISEF · 2025
Biomedical and Health Sciences
Breast cancer is the most common cancer worldwide and a complex disease characterized by genetic heterogeneity. Despite advancements in cancer management, the risk of recurrence and death re…
ISEF · 2025
Biomedical and Health Sciences
STAC3, known as Native American Myopathy, was first identified within the Lumbee tribe of North Carolina and is known to be an inherited mutation that causes congenital myopathy and musculos…
ISEF · 2025
Biomedical and Health Sciences
Helicobacter pylori is a bacterial strain that attaches to gastric mucosal cells through its BabA adhesin, which begins growth of colonies that increase risk of peptic ulcers and gastric or…
ISEF · 2025
Translational Medical Science
CTE, a progressive neurodegenerative condition from repetitive head impacts in sports, lacks preventive interventions. This research examines curcumin and CoQ10's neuroprotective effects in…
ISEF · 2025
Biomedical and Health Sciences
The therapeutic value of traditional plants in the Philippines remains underexplored. Thus, this study investigates the neuroprotective potential of Premna odorata leaf extract for Alzheimer…
ISEF · 2025
Translational Medical Science
The widespread use of drugs, together with their limited specificity and poor biodistribution, poses significant challenges. Antibiotic resistance, aggravated by decades of uncontrolled cons…
ISEF · 2025
Biomedical and Health Sciences
Cardiovascular disease (CVD) causes 20.5 million deaths annually and imposes significant economic burdens due to rising healthcare costs. While pharmacological treatments and surgeries are t…