Browse real student projects, abstracts, and awards.
ISEF · 2026
Translational Medical Science
Alzheimer’s disease (AD) is projected to affect 150 million people by 2050 and is characterized by the accumulation of neurotoxic beta-amyloid (Aß) plaques in the brain, leading to severe me…
ISEF · 2026
Biomedical and Health Sciences
(This project was implemented in the city of Duhok, in the Kurdistan Region of Iraq, to solve the health problems caused by wastewater. It aims to treat the polluted water, recycle it, and m…
ISEF · 2026
Biomedical and Health Sciences
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by motor dysfunction and neuron loss, with limited current treatments, revealing a critical gap. Heat shock…
ISEF · 2026
Biomedical and Health Sciences
While racial smoking disparities are well-documented, traditional socioeconomic models often overlook the discordance between educational attainment and income. This study investigates ‘stat…
ISEF · 2026
Biomedical and Health Sciences
Purpose: Antibiotic resistance is growing. Bacteriophages (phages) are viruses that infect bacteria; using phages and antibiotics together has a synergistic effect. This study applied phages…
ISEF · 2026
Biomedical and Health Sciences
In the US, 1 in 3 individuals develops cancer in their lifetime. Yet, drug failure rates remain near 90%. Deciphering immune-cancer interactions within the tumor microenvironment (TME) is im…
ISEF · 2026
Translational Medical Science
Atypical Chemokine Receptor 1 (ACKR1/DARC) is a non-signaling chemokine receptor expressed on erythrocytes and endothelial cells. In tumors, ACKR1 modulates inflammation, chemokine gradients…
ISEF · 2026
Translational Medical Science
Retinal degenerative diseases (RDDs) affect 300 million patients worldwide. Current imaging techniques detect RDDs in late stages after significant vision loss. Approximately 40% of Retinal…
ISEF · 2026
Translational Medical Science
Melanoma is the most fatal type of skin cancer, taking over 50,000 lives annually. While advances in checkpoint immunotherapy have decreased mortality rates, it is difficult to determine whi…
ISEF · 2026
Translational Medical Science
Can neuron resilience be predicted as topological failure of cellular identity? Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease marked by TDP-43 aggregation and moto…
ISEF · 2026
Translational Medical Science
Dementia affects 55 million people globally, projected to reach 139 million by 2050. Although deep learning models achieve 90–98% accuracy for dementia classification, clinical adoption is h…
ISEF · 2025
Translational Medical Science
Neurodegenerative disorders like Alzheimer’s disease affect approximately 55 million people worldwide and are expected to double every 20 years. Standard detection methods, such as cerebrosp…
ISEF · 2025
Translational Medical Science
Sudden cardiac arrest (SCA) remains a significant health concern, accounting for over 436,000 deaths annually in the United States. An electrocardiogram (EKG) signal can help to identify ris…
ISEF · 2025
Translational Medical Science
In the last decade, the world has plunged into an opioid epidemic, with overdose deaths surging, amplified by the rise of synthetic drugs. In 2019, opioids accounted for 80% of global drug-r…
ISEF · 2025
Biomedical and Health Sciences
This project introduces a low-cost, portable diagnostic device for the rapid and accurate detection of pandemic-causing diseases. During the COVID-19 pandemic, millions of people lacked acce…
ISEF · 2025
Translational Medical Science
Coagulopathy defined as abnormal blood coagulation can cause thrombosis (hypercoagulation) or hemorrhage (hypocoagulation) leading to death. Current assays that provide a complete assessment…
ISEF · 2025
Biomedical and Health Sciences
In 2023, the Brazilian Amazon had the worst drought in history. People from the rural and indigenous areas suffered from many problems, especially hunger. In search of a food alternative fro…
ISEF · 2025
Translational Medical Science
Artificial Intelligence (AI) models like Convolutional Neural Networks (CNNs) are becoming powerful tools in medical imaging, but their “black box” nature limits clinical use. Doctors need t…
ISEF · 2025
Translational Medical Science
In recent years, research has demonstrated that the gut microbiome has an important role in normal brain function. This opens up possibilities for novel treatments of Alzheimer's, which affe…
ISEF · 2025
Translational Medical Science
Brain tumors affect thousands annually, with approximately 95,000 primary brain tumor cases diagnosed each year in the U.S. Diagnostic imaging errors affect an estimated 40 million patients…
ISEF · 2025
Translational Medical Science
The prevalence of diseases such as diabetic retinopathy (DR), glaucoma, and age-related macular degeneration (AMD) is rapidly increasing worldwide, with over 700 million people expected to f…
ISEF · 2025
Biomedical and Health Sciences
This project is a continuation of last year. The changes made include new testing and new cast designs. This year compression testing was done on the casts. To test this a force plate was us…
ISEF · 2025
Biomedical and Health Sciences
Posterior capsule opacification (PCO) is a major complication of cataract surgery, driven by the epithelial-to-mesenchymal transition (EMT). In this study, I investigated the mechanistic eff…
ISEF · 2025
Translational Medical Science
The Social Vulnerability Index (SVI) measures health vulnerability through a composite score from 0-1 based on four subcategories: socioeconomic status, household characteristics, housing ty…
ISEF · 2025
Translational Medical Science
Brain tumors represent a critical health challenge, affecting thousands of individuals annually and often leading to significant harm and mortality. Such challenges highlight the need for in…
ISEF · 2025
Biomedical and Health Sciences
Escherichia coli (E. coli) is one of the primary bacterial causes of urinary tract infections (UTIs), accounting for 75–95% of cases. Conventional antibiotics are commonly used for treatment…
ISEF · 2025
Translational Medical Science
Major Depressive Disorder negatively affects millions worldwide by decreasing productivity, degrading physical well-being, and increasing the risk of suicide by 60%. Moreover, miscalculating…
ISEF · 2025
Translational Medical Science
Cancer remains a leading cause of death worldwide, with approximately 10 million fatalities annually. Whole Slide Imaging (WSI) and Deep Learning can enhance histopathological analysis, enab…
ISEF · 2025
Translational Medical Science
Alzheimer's disease (AD) remains difficult to diagnose in its early stages. Current diagnostic approaches often miss subtle early symptoms, delaying intervention. In this research, a novel m…
ISEF · 2025
Biomedical and Health Sciences
Anthropogenic open burning is known to release hazardous chemicals and has been associated with an increased prevalence of cardiopulmonary issues. For example, studies show that veterans who…