Browse real student projects, abstracts, and awards.
ISEF · 2018
Biomedical and Health Sciences
TMEV, a murine single-stranded positive sense RNA virus, is a model for both multiple sclerosis (MS) and epilepsy, as it results in a demyelinating encephalomyelitis in the CNS, resembling M…
ISEF · 2018
Biomedical and Health Sciences
According to the National Cancer Institute, breast cancer is the most common malignancy in United States women, accounting for more than 40,000 deaths each year. The main cause of death in b…
ISEF · 2018
Biomedical and Health Sciences Third Award
Alzheimer’s Disease affects an estimated 5.4 million people, making it the sixth leading cause of death in the United States. Seeking to increase therapeutic gains, near infrared light (NIR)…
ISEF · 2018
Translational Medical Science
Cardiovascular system diseases are leading causes of mortality worldwide and in all age groups. Moreover, specialists believe that in 90% of cases, cardiovascular diseases can be cured if di…
ISEF · 2018
Translational Medical Science
Purpose: The experiment identified Stearoyl-CoA desaturase 1 (SCD1) as a novel molecular target in Serous Ovarian Carcinoma determined the potential of SSI-4, an SCD1 inhibitor, as a novel m…
ISEF · 2018
Biomedical and Health Sciences
Next-generation intracellular delivery solutions are necessary and will provide essential roles in drug therapeutic applications as well as being critical components of genome editing approa…
ISEF · 2018
Translational Medical Science
The presence of circulating tumor cells (CTCs) in a patient's blood may indicate the aggressiveness of metastatic cancer, and the detection of CTCs can assist physicians in decision making a…
ISEF · 2018
Biomedical and Health Sciences Fourth Award
Diabetes is a multi-factorial disorder, characterized by chronic elevation of glucose in the blood. Chronic exposure to high glucose (HG) is a leading cause of cell damage, which is responsi…
ISEF · 2018
Translational Medical Science Fourth Award
A rapid, inexpensive, and non-invasive warning mechanism for imminent stroke and epileptic seizures was developed using gold nanoparticle-hydrogel composites. Stroke is the third leading cau…
ISEF · 2018
Biomedical and Health Sciences Second Award
Cancer immunotherapy is an important alternative to traditional treatments such as chemotherapy and radiation, reducing the toxicity and negative side effects. By eliciting an immune respons…
ISEF · 2018
Biomedical and Health Sciences
The goal of this study was to analyze the expression of SLUG in ovarian cancer. The null hypothesis was that expression of SLUG would be the same between the two tissue types. This study use…
ISEF · 2018
Translational Medical Science
Bisphenol A (BPA), a widely used plastic monomer, is a known estrogen disruptor, which has massive potential implications for public health. Estrogen can cause R-loops, a three-stranded nucl…
ISEF · 2018
Biomedical and Health Sciences Fourth Award
Alzheimer’s disease (AD) is one of the most common forms of dementia. The progression of AD occurs in the brain as well as in the eye. The retinal pigment epithelial (RPE) cells were recentl…
ISEF · 2018
Biomedical and Health Sciences
Pneumonia affects 450 million people worldwide. It is believed that elderly individuals, 65 years or older, are more susceptible to acquiring the disease, due to changes in the aging immune…
ISEF · 2018
Translational Medical Science
Coronary artery bypass grafting (CABG) is the most common type of open heart surgery performed in the United States, and the surgery most commonly involves harvesting the saphenous vein and…
ISEF · 2018
Translational Medical Science
Parkinson’s disease (PD), the second most common neurodegenerative ailment is characterized by muscular contractions and involuntary movement (dyskinesia). Its hallmarks include loss of move…
ISEF · 2018
Translational Medical Science
Antibiotic resistance has been named as one of the greatest threats the modern public health system faces. One method of tackling growing antibiotic resistance is to explore substances overl…
ISEF · 2018
Biomedical and Health Sciences
Hereditary hemorrhagic telangiectasia (HHT, Rendu-Osler-Weber syndrome) is a genetic vascular disorder arising from endothelial cell proliferation and hypervascularization. Patients with HHT…
ISEF · 2018
Biomedical and Health Sciences
Osteoarthritis (OA) is a musculoskeletal disease often caused by overuse or injury but recent literature has suspected G protein coupled receptor (GPCR) signaling of cell surface receptors a…
ISEF · 2018
Biomedical and Health Sciences First Award
Coronary Artery Disease (CAD), an aging related detriment, is the most common cause of mortality in the world. In addition, chemotherapy jeopardizes cardiovascular integrity and was shown to…
ISEF · 2018
Translational Medical Science
The leaves of Clinacanthus nutans (Sabah Snake Grass) have long been used traditionally in Asia for treatment of skin rashes and snake bites. This project investigates the effect of Clinacan…
ISEF · 2018
Translational Medical Science
In the United States, 23,830 new primary malignant tumors of the brain and central nervous system (CNS) are expected to be diagnosed in 2018, according to the Central Brain Tumor Registry of…
ISEF · 2018
Biomedical and Health Sciences
Around the world, sleep deprivation causes employees to be less efficient, accident prone, and costs companies profit. This occurs because when people are sleepy they don't communicate well…
ISEF · 2018
Biomedical and Health Sciences
Effective epithelialization is essential to the restoration of tissue after a chronic injury to ensure wound healing. Examination of Fidgetin Like-2 (FL2), a novel microtubule depolymerase,…
ISEF · 2018
Biomedical and Health Sciences
Heart disease is the leading cause of death in women worldwide. However, the molecular pathway that causes different effects in men and women during a myocardial infarction (MI) is unknown.…
ISEF · 2018
Translational Medical Science
Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype associated with a poor prognosis and reduced hormone therapy efficacy. Although the current standard treatment for…
ISEF · 2018
Translational Medical Science
Hodgkin Lymphoma (HL) is a blood cancer that develops in the lymphatic system when a lymphocyte undergoes a malignant transformation and develops a DNA mutation. HL makes up about 1% of all…
ISEF · 2018
Biomedical and Health Sciences
Colorectal cancer is the third most common type of cancer in the US. Additionally, early-onset colorectal cancer has been increasing in incidence, unlike most other types of cancer, by about…
ISEF · 2018
Biomedical and Health Sciences
Peanut allergy is common. Avoidance of peanut is the mainstay of treatment, although accidental exposure frequently occurs. Public schools and commercial airliners have initiated “peanut-fre…
ISEF · 2018
Translational Medical Science
Strep throat infects millions of people every year. Due to the similarity of symptoms between bacterial and viral infections, a rapid diagnosis test to identify Group A Streptococcus (GAS) f…