Browse real student projects, abstracts, and awards.
ISEF · 2019
Translational Medical Science
When a cardiac injury occurs as a result of hemolysis, the heart suffers from an intramyocardial hemorrhage and left ventricular remodeling. Studies are showing that the result of this damag…
ISEF · 2019
Biomedical and Health Sciences Third Award
Acute kidney injury (AKI) is a common complication in hospitalized patients, with mortality rates as high as 50% in intensive care unit patients; therefore, early detection of this condition…
ISEF · 2019
Translational Medical Science
The SMART System is designed to improve radiotherapy cancer treatment. This is performed through the use of two novel devices, forming an integrated system. The Specialised Magnetic Array fo…
ISEF · 2019
Biomedical and Health Sciences
Regarding feminine hygiene products, the “FDA recommends that tampons be free of harmful chemicals and any pesticide and herbicide residues,” (2018) with no specific regulations that compani…
ISEF · 2019
Translational Medical Science Fourth Award
Glioblastoma multiforme (GBM), the most common type of primary brain tumor, is universally fatal with median survival ranging from 9–16 months. Although a significant effort has been focused…
ISEF · 2019
Biomedical and Health Sciences
According to a study published in 2016 by Pendse et al., while the number of newly infected individuals in the majority of countries in Southeast Asia has been decreasing, more and more indi…
ISEF · 2019
Translational Medical Science
Biomarkers are extremely important in medical diagnostics, as they can help monitor a patient's medical status. Heart disease and sepsis, for example, can be identified by a spike in the con…
ISEF · 2019
Translational Medical Science
A systematic review indicates dextrose injections beneficially treat knee osteoarthritis; one possible mechanism is cartilage regeneration. Scientists have conducted few in vitro studies and…
ISEF · 2019
Translational Medical Science Third Award
I identified physical features in a candidate cancer vaccine that lead to improved anti-tumor response. Though cancer vaccines present an attractive strategy to coax the immune system to tar…
ISEF · 2019
Translational Medical Science Fourth Award
Circulating tumor DNA in blood holds promise as a cancer-specific biomarker. However, detection of ultra-low mutation allelic frequency (MAF) of ctDNA at early stages of cancer is infeasible…
ISEF · 2019
Biomedical and Health Sciences Fourth Award
Sickle Cell Disease (SCD) is a hereditary blood disorder. People with SCD experience pain crises, hypercoagulation, and strokes, and suffer dramatically shortened lifespans. SCD causes indiv…
ISEF · 2019
Biomedical and Health Sciences
Aurora Kinase A, a serine-threonine protein kinase, is primarily responsible for regulation of cell proliferation. When overexpressed, it can cause an uncontrollable increase in cellular pro…
ISEF · 2019
Translational Medical Science
Neuroinflammation occurs when microglia become activated and release neurotoxic factors. This process plays a key role in a number of neurological disorders, including Alzheimer’s disease, P…
ISEF · 2018
Biomedical and Health Sciences Second Award
Galactosemia is a life-threatening genetic disease in which patients cannot metabolize galactose, a sugar found abundantly in milk, fruits, and vegetables. As a result, galactose builds up t…
ISEF · 2018
Biomedical and Health Sciences Second Award
This project targets Schistosomiasis, a parasitic disease second to Malaria in economic effect in developing countries. Doctors diagnose Schistosomiasis by using microscopes to count the num…
ISEF · 2018
Biomedical and Health Sciences
Periodontitis, also referred to as periodontal disease, affects 42.7% (64 million) of the population in the United States. Periodontitis is a gingival infection resulting in damage to the so…
ISEF · 2018
Translational Medical Science
Today, sport activities have become very important on human. The most significant measure of sport arising from competitive and rivalling instincts and motivations of human being is the perf…
ISEF · 2018
Biomedical and Health Sciences Third Award
Hyperpolarization-activated cyclic nucleotide–gated (HCN) channels are voltage-gated channels in cell membranes of the heart and brain. The Ih current, also called the pacemaker current, pla…
ISEF · 2018
Biomedical and Health Sciences
Cancer is a major public health problem and is the second most leading cause of death worldwide. Today, treatments available to us include chemotherapy and surgery which are both vastly expe…
ISEF · 2018
Translational Medical Science
Optical Coherence Tomography (OCT) is relatively new non-invasive imaging technique that can be used for a variety of medical diagnosis. OCT is cost-effective and requires fewer resources th…
ISEF · 2018
Translational Medical Science
Photodynamic therapy (PDT) is a form of cancer treatment that involves administering a photosensitizing drug and irradiating it with an external light source. Upon exposure, the photosensiti…
ISEF · 2018
Biomedical and Health Sciences
Hydrogen peroxide (H2O2) is crucial indicator of inflammatory diseases due to its extensive role in the inflammation process. However, despite its importance as a diagnostic indicator, there…
ISEF · 2018
Biomedical and Health Sciences Fourth Award
Neuroblastoma(NB) is a pediatric cancer present in children under the age of 16, responsible for a disproportionate 15% of all childhood cancer deaths worldwide. Traditionally cells differen…
ISEF · 2018
Translational Medical Science Fourth Award
Lipopolysaccharides (LPS) are harmful biomolecules found on the surface of gram-negative bacteria and are responsible for over 50% of cases of sepsis, the leading cause of death in US hospit…
ISEF · 2018
Translational Medical Science
Breast cancer is the most common diagnosed cancer in women worldwide. Despite the success of surgery to treat early stages of breast cancer, later stages often require systemic chemotherapy…
ISEF · 2018
Translational Medical Science Fourth Award
Purpose: Ebola virus (EBOV) can cause severe and fatal hemorrhagic fever in humans. Being capable of causing large-scale epidemics, EBOV also emerges as a global security threat. Therefore,…
ISEF · 2018
Translational Medical Science
Hypodiploid B-ALL is a high-risk form of acute leukemia with a dismal prognosis and an 8-year survival rate of only 37%. Because standard chemotherapy is largely ineffective, there is an urg…
ISEF · 2018
Translational Medical Science Third Award
Neurometabolic and vascular changes have been shown to pre-date amyloid deposition and cognitive impairment in Alzheimer’s disease by several decades. However, these changes are not well cha…
ISEF · 2018
Biomedical and Health Sciences
Diffuse Large B Cell Lymphoma (DLBCL) is the most common form of Non-Hodgkin’s Lymphoma. Current chemotherapy fails in approximately 50% of patients; consequently, understanding DLBCL pathog…
ISEF · 2018
Biomedical and Health Sciences
Mosquito borne diseases such as chikungunya, jaundice, malaria, and dengue are common in my country. Therefore, we have to be alert of its breeding grounds especially in our neighborhood. Th…