Browse real student projects, abstracts, and awards.
ISEF · 2026
Biomedical and Health Sciences
Food allergy (FA) affects 18% of the population and is driven by type-2 inflammation, epithelial barrier dysfunction, and tight junction (TJ) disruption. Recent studies identify Zonulin and…
ISEF · 2026
Translational Medical Science
Psoriasis silently torments 125 million people worldwide, yet current therapies such as corticosteroids and biologics thin the skin, suppress the immune system, and lose efficacy over time,…
ISEF · 2026
Translational Medical Science
Anxiety is an ever-growing issue plaguing modern society as it becomes more prevalent in young adults and adolescents, particularly Generalized Anxiety Disorder (GAD). Despite the existence…
ISEF · 2026
Translational Medical Science
Lung cancer remains the leading cause of cancer-related mortality worldwide, and early detection significantly improves survival outcomes. Subsolid pulmonary nodules, including ground-glass…
ISEF · 2026
Translational Medical Science
Headache disorders are among the top three most common neurological conditions, affecting 40% of the global population, yet 50–80% of migraine patients are misdiagnosed due to fragmented dia…
ISEF · 2026
Biomedical and Health Sciences
The gut and adipose tissue work in concert to modulate metabolic health and the immune system by producing short-chain fatty acids (SCFAs). FFAR2 signaling plays a vital role in regulating m…
ISEF · 2026
Translational Medical Science
Alzheimer's disease (AD) impacts approximately 55 million people globally and is predicted to affect 139 million individuals by 2050. As most diagnoses occur after substantial neurodegenerat…
ISEF · 2026
Translational Medical Science
Purpose: Laryngeal squamous cell carcinoma (LSCC) causes over 100,000 deaths annually worldwide. While adjuvant radiotherapy after surgical resection can reduce the risk of recurrence and im…
ISEF · 2026
Biomedical and Health Sciences
Microplastics have been a growing problem within the biomedical and health fields. However, mechanistic links between dietary exposure, molecular interaction, physiological impact, and mitig…
ISEF · 2026
Biomedical and Health Sciences
Music reduces stress and improves health by affecting the autonomic nervous system, and transcriptomic studies show it increases alpha-synuclein (SNCA), which regulates neuronal activity. Al…
ISEF · 2026
Biomedical and Health Sciences
Schizophrenia is a chronic neurodevelopmental disorder. In low-resource settings like Zimbabwe, stigma and limited psychiatric infrastructure delay diagnosis. This study investigated whether…
ISEF · 2026
Translational Medical Science
Alzheimer’s disease (AD) causes the gradual loss of neurons, which leads to memory and cognitive problems. Due to the inability to replace the lost neurons, current treatments cannot stop or…
ISEF · 2026
Translational Medical Science
Intracranial aneurysms (IAs) often rupture before detection, causing hemorrhagic stroke that is fatal in 50% of cases. Expensive ($800 - $8400) hospital-based diagnostic tests are conducted…
ISEF · 2026
Translational Medical Science
Schizophrenia is a chronic neurodevelopmental disorder affecting approximately 24 million people worldwide. Despite its severity, its biological mechanisms remain poorly understood, and curr…
ISEF · 2026
Translational Medical Science
Purpose: Neuroblastoma and glioblastoma are highly aggressive malignant neural tumors affecting pediatric and adult populations respectively. Both are associated with very poor prognoses des…
ISEF · 2026
Translational Medical Science
Alzheimer's disease (AD) is a progressive neurodegenerative disease that continues to be difficult to diagnose in early stages. Despite studies demonstrating that when caught early, cognitiv…
ISEF · 2026
Translational Medical Science
Stroke, the 2nd leading cause of death(>7M) and 3rd leading cause of disability (94M) worldwide, is a time-critical emergency. Rapid, accurate stroke detection and severity assessment during…
ISEF · 2026
Translational Medical Science
Parkinson's Disease (PD) is a neurodegenerative disorder that impairs motor function, making early detection crucial for slowing disease progression and managing symptoms. However, current d…
ISEF · 2026
Translational Medical Science
Microalgae are unicellural organisms that are found both in marine and freshwater ecosystems, ranging from tropical water habitats to subpolar areas. They have recently gained attention due…
ISEF · 2026
Biomedical and Health Sciences
Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness, characterized by progressive optic nerve damage often without symptoms until significant vision loss occurs.…
ISEF · 2026
Translational Medical Science
Embryo selection for Frozen Embryo Transfer (FET) is routinely based on subjective parameters. In most modern In-Vitro Fertilization (IVF) labs a quantitative approach for embryo selection i…
ISEF · 2026
Translational Medical Science
Cancer remains one of the leading causes of mortality due in part to the limitations of current diagnostic methods, which often rely on single biomarkers and fail to capture the systemic bio…
ISEF · 2026
Translational Medical Science
Breast cancer recurrence rates reach up to 50%, yet existing clinical tools rely on single modality data or repeated medical check-ups. My model, OncoTwin, is a novel recurrence-risk predict…
ISEF · 2026
Translational Medical Science
Alzheimer's is a neurodegenerative disease characterized by causes such as amyloid plaque accumulation, microglial dysfunction, and chronic neuroinflammation. Current treatments target the e…
ISEF · 2026
Biomedical and Health Sciences
Atherosclerosis is a condition characterized by a buildup of plaque in the arteries. Changes in blood flow cause endothelial cells to become atheroprone (susceptible to atherosclerosis patho…
ISEF · 2026
Translational Medical Science
In the spring of 2025, my aunt tragically passed away from a long and hard-fought battle with breast cancer. My grief inspired me to develop a way to help diagnose breast cancer more efficie…
ISEF · 2026
Translational Medical Science
Most healthcare efforts focus on diagnosis, followed by treatment, and subsequently the post-treatment phase. However, only a limited subset of individuals who prioritize their health pay at…
ISEF · 2026
Translational Medical Science
Alzheimer’s disease is a progressive and ultimately fatal neurodegenerative disorder affecting over 55 million people worldwide. Although early diagnosis is critical, up to 75% of dementia p…
ISEF · 2026
Biomedical and Health Sciences
Fibromyalgia is a chronic disorder characterized by widespread pain, fatigue, and cognitive impairments. Current treatments primarily target symptoms rather than underlying pathology. Growin…
ISEF · 2026
Biomedical and Health Sciences
Carotenoids are lipid-soluble dietary pigments and vitamin A precursors that regulate gene transcription via RARA and RXRA nuclear receptors. Retinoid signaling controls differentiation, pro…