Browse real student projects, abstracts, and awards.
ISEF · 2019
Translational Medical Science
We are outnumbered; trillions of non-human microbes live on and within our bodies. Combined they consist of 3.3 million genes while the human genome has only 23,000 genes. The human microbio…
ISEF · 2019
Biomedical and Health Sciences
Ih currents in Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels play a crucial role in neuronal activity and synaptic transmission in the central nervous system. Autism spe…
ISEF · 2019
Biomedical and Health Sciences
Glioblastoma Multiforme (GBM) is the most common and aggressive malignant brain tumor, accounting for 52% of all primary brain tumors. Studies show that earlier diagnosis can lead to a bette…
ISEF · 2019
Translational Medical Science
Textiles and human evolution are entwined with each other for protection from natural forces and personal hygiene/attraction. Consumers today desire more scientifically advanced clothes that…
ISEF · 2019
Biomedical and Health Sciences
The purpose of this experiment is to find potential mutagenic properties within the pairing of Iron Chloride and Ascorbic Acid in vitamin supplementation, and to create an application toward…
ISEF · 2019
Translational Medical Science
Early Onset Scoliosis (EOS) is defined as the lateral curvature of the spine, greater than 10 degrees, in children less than 10 years and is accompanied by vertebral rotation, creating a com…
ISEF · 2019
Biomedical and Health Sciences
Melanoma is the deadliest skin cancer with over 9,000 deaths per year, but melanoma detected early results in over 90% chance of cure. Currently, a biopsy is the most common method of melano…
ISEF · 2019
Translational Medical Science
Sickle cell anemia (SCA) is recessive autosomal inherited life-threatening hemoglobinopathy. Normally the average life of RBC is 100-120 days in a healthy human whereas, it is as low as 4-5…
ISEF · 2019
Biomedical and Health Sciences
Diesel Exhaust Particles (DEPs) are a form of air pollution which cause increased production of reactive oxygen species (ROS) in lung cancer cells, which leads to oxidative stress and eventu…
ISEF · 2019
Biomedical and Health Sciences Fourth Award
Major depressive disorder (MDD) is a psychiatric condition affecting 6.7% of the U.S. population and costing over $210B domestically each year. For decades, research of MDD has majorly conce…
ISEF · 2019
Translational Medical Science Fourth Award
Retinopathy of Prematurity (ROP), observed in infants born preterm with low birth weight, is a leading cause of blindness worldwide. ROP shows no external signs or symptoms. Currently, the g…
ISEF · 2019
Biomedical and Health Sciences
Americans ownership of smart phones increases rapidly by the year. Due to this rapid increase Checking your phone becomes constant habit throughout the day. The purpose is to identify how ou…
ISEF · 2019
Biomedical and Health Sciences Fourth Award
Precision and personalized medicine are emerging approaches for cancer therapeutics. By characterizing patients’ risk for adverse developments such as tumor progression, specialized treatmen…
ISEF · 2019
Translational Medical Science Fourth Award
Catheters are the most used devices in treating hospitalized patients and in hemodialysis procedures. However, its use represents a potential risk for blood infections (possibly sepsis or se…
ISEF · 2019
Biomedical and Health Sciences
The need for an alternative method of pain control has become critical in the United States due to the opioid epidemic. The CDC has created guidelines with patient risk categories related to…
ISEF · 2019
Biomedical and Health Sciences Third Award
Cancer has two halves: malignant cells that initiate oncogenesis, and cancer stromal cells that form the tumor microenvironment. Isocitrate dehydrogenases (IDHs) are enzymes in normal cellul…
ISEF · 2019
Translational Medical Science
Rapamycin is an immunosuppressant that inhibits mTOR (the mammalian target of rapamycin) and extends lifespan in organisms such as worms, flies, and mice. While it is known that rapamycin’s…
ISEF · 2019
Biomedical and Health Sciences
The purpose of this experiment was to test whether foods rich in High Density Lipoproteins (HDL’s) cholesterol would be successful in treating heart disease. Because heart disease is caused…
ISEF · 2019
Biomedical and Health Sciences
At what point do our psychological needs compel us to ignore possible health risks? Could we be turning a blind eye to the possibly harmful effects caused by a simple communication device? A…
ISEF · 2019
Translational Medical Science
Head and neck squamous cell carcinoma (HNSCC) comprises approximately 90% of all head and neck cancers and represents the sixth most common type of cancer worldwide. Surgery, radiotherapy an…
ISEF · 2019
Biomedical and Health Sciences
Purpose: There is in an estimated 7.9 million bone fractures annually in which 5-10% of these result in delayed healing and progression to chronic nonunions. One factor that has previously b…
ISEF · 2019
Translational Medical Science
Deregulation of the tumor suppressor p27kip1 results in the proliferation of common and aggressive cancers such as breast and prostate cancer. The purpose of this study is to investigate the…
ISEF · 2019
Biomedical and Health Sciences Fourth Award
Antibiotic resistance is a growing public health challenge which affects about two million people in the U.S. annually. The search for new antibacterial agents is focusing on small drug mole…
ISEF · 2019
Biomedical and Health Sciences
Ovarian germ cell tumors are tumors that arise from the egg cells of the ovaries. There are different types of ovarian germ cell tumors including mature and immature teratomas, metastatic tu…
ISEF · 2019
Translational Medical Science
Hepatocellular carcinoma (HCC) is the most common form of liver cancer and is the third leading cause of cancer-related death worldwide. Over 90 percent of these cancer-related deaths are du…
ISEF · 2019
Translational Medical Science
Pneumonia emerges as the leading cause of death in children under five years of age worldwide, accounting for more than 1.6 million deaths each year in this age demographic. A combined 18% o…
ISEF · 2019
Biomedical and Health Sciences
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) is an inheritable myocardial disease characterized by fibrofatty replacement of cardiomyocytes and is the leading cause of sudden cardi…
ISEF · 2019
Translational Medical Science
Piperlongumine (PLM) is a compound derived from the long pepper that can selectively kill cancer cells and cancer stem cells, which are often responsible for relapses. PLM has the potential…
ISEF · 2019
Translational Medical Science
Cardiovascular disease (CVD) is the leading cause of death worldwide, killing 17.9 million people annually and costing billions of dollars. The main cause of CVD is atherosclerosis, the buil…
ISEF · 2019
Biomedical and Health Sciences
Glioblastoma is a brain cancer that is resistant to treatment due to the migration of individual glioblastoma cells throughout the brain. This study measured the effect of NE-100, a sigma-1…