Browse real student projects, abstracts, and awards.
ISEF · 2020
Translational Medical Science
Cancer has remained as one of the world's leading causes of death and although medical treatments exist, many of the current methods have cytotoxic effects to not only the cancer cells, but…
ISEF · 2020
Biomedical and Health Sciences
The survival rate for patients diagnosed with gliomas (the most common type of brain tumor) is 5.6%. Gliomas are primarily driven by pathways like NF-kB signaling, which plays a key role in…
ISEF · 2020
Biomedical and Health Sciences
Rheumatoid Arthritis is a debilitating autoimmune disease in which the body— a person’s immune system— attacks its own synovium. Rheumatoid arthritis results in heightened inflammatory respo…
ISEF · 2020
Translational Medical Science
Ivermectin, awarded the Nobel Peace Prize for Physiology or Medicine in 2015, was originally used as an anthelmintic. Ivermectin was invented by William Campbell and Satoshi Omura to treat p…
ISEF · 2020
Translational Medical Science
Research shows that mammograms can be 80-90 percent accurate in detecting breast cancer in women without dense tissue, however the accuracy of this metric drops drastically down to nearly 50…
ISEF · 2020
Translational Medical Science
Millions of people worldwide suffer from chronic pain with few treatments other than opioids available. Photobiomodulation (PBM) and electroacupuncture (EA) are two treatments for chronic pa…
ISEF · 2020
Biomedical and Health Sciences
Introduction: Children with mutations in mannose phosphate isomerase (MPI) develop early liver fibrosis that can progress to require liver transplantation. We have previously shown that MPI…
ISEF · 2020
Biomedical and Health Sciences
The K27M mutation in histone H3.3 drives incurable glioblastomas in children called Diffuse Intrinsic Pontine Gliomas (DIPG). Research in human cells shows that a deficiency in H3.3 protein…
ISEF · 2020
Biomedical and Health Sciences
Coronary Artery Disease (CAD) is one of the leading causes of death worldwide, accounting for 31% of all deaths globally in 2016. This work will investigate the possibility of detecting CAD…
ISEF · 2020
Translational Medical Science
Hepatoblastoma is the most common liver tumor in children. Those with relapsed or metastatic disease continue to have a poor prognosis and require novel therapies to improve outcomes. PIM ki…
ISEF · 2020
Biomedical and Health Sciences
Right ventricular (RV) dysfunction is the main determinant of mortality in patients with pulmonary arterial hypertension (PAH); yet, there is limited information on the role of RV inflammati…
ISEF · 2020
Translational Medical Science
The aim of our work was to create an affordable and easy-to-use device for the early diagnosis of transparency disorders in the optical media of the human eye. As a result of the analysis of…
ISEF · 2020
Translational Medical Science
Pancreatic cancer (PC) is the fourth leading cause of cancer death in the United States because it’s five-year survival rate is 8.9%. This occurs because of late diagnosis which is affiliate…
ISEF · 2020
Translational Medical Science
Retinal diseases such as glaucoma and diabetic retinopathy (DR) currently devastate the developing world, causing permanent visual impairment when left undiagnosed and untreated. Glaucoma is…
ISEF · 2020
Translational Medical Science
I was fascinated by my community’s use of local plants for medicinal purposes. Elders in my community have used (and are still using) bush medicine whenever any of our people get sick. I wan…
ISEF · 2020
Biomedical and Health Sciences
Non-small cell lung cancer (NSCLC) remains one of the most prominent causes of cancer-related deaths across populations despite advancing treatment options. NSCLC is typically treated with a…
ISEF · 2020
Translational Medical Science
Photodynamic therapy (PDT) is successfully used in clinical oncology. This treatment uses photosensitizers and light of a specific wavelength. On the light, photosensitizers generate reactiv…
ISEF · 2020
Biomedical and Health Sciences
Stabilizers such as gelatin is usually added to yogurt to improve the texture of the yogurt by increasing its viscosity and preventing syneresis. However, gelatins used in yogurt are derived…
ISEF · 2020
Translational Medical Science
Radiology is the field of medicine concerned with the interpretation of imaging of the human body for disease diagnosis. Most major forms of medical imaging scans occur within one hour or le…
ISEF · 2020
Translational Medical Science
Diabetic retinopathy (DR) is a complication of diabetes that can lead to blindness and is the leading cause of blindness in working-age adults. DR will affect most type-1 diabetic (T1D) pati…
ISEF · 2020
Translational Medical Science
The drawback of chemotherapy for treating cancer is that the cancerous cells acquire drug resistance after constant exposure to the drug, making them impervious to further dose escalation. M…
ISEF · 2020
Biomedical and Health Sciences
Modern diagnosis of glioma tumors requires several MRI sequences of the brain, which can be costly, burdensome to the patient, and provide toxic risks due to the presence of metallic, often…
ISEF · 2020
Biomedical and Health Sciences
Sodium benzoate is one of the most commonly used preservatives in the food industry. Although the compound is recognized as safe by the FDA, the effects of sodium benzoate on human health ha…
ISEF · 2020
Biomedical and Health Sciences
Aspirin is an important drug in the medical field. It is used to relieve pain, reduce fever but also to prevent blood clots, lowering the risk of heart attack or stroke in people who had sur…
ISEF · 2020
Biomedical and Health Sciences
Cancer’s evasion of traditional therapies due to the constantly changing phenotype of cancer cells is becoming a major clinical problem and is responsible for 90% of cancer deaths worldwide.…
ISEF · 2020
Translational Medical Science
Planaria are well known for their phenomenal regeneration abilities. Because of the presence of totipotent stem cells (also known as neoblasts) throughout their body, they are commonly used…
ISEF · 2020
Translational Medical Science
Small-cell lung cancer (SCLC) is a highly aggressive form of lung cancer. Despite available chemotherapeutics, resistance develops rapidly, accounting for a 6%, 5-year survival rate. Strateg…
ISEF · 2020
Translational Medical Science
This study developed and characterized a novel proteolysis targeting chimera (PROTAC) incorporating a beta hairpin sequence motif. PROTACs facilitate the proteasomal degradation of ‘undrugga…
ISEF · 2020
Biomedical and Health Sciences
Immunotherapy is a treatment in which the body’s immune cells, are stimulated to fight diseases such as cancer. Several immunotherapies have been developed with the aim of helping T Cells ta…
ISEF · 2020
Biomedical and Health Sciences
Nanoparticles (NPs) are attractive cancer drugs but cannot target cancer cells, causing side effects in cancer therapy. To tackle this challenge, I developed NPs that could kill breast cance…