Browse real student projects, abstracts, and awards.
ISEF · 2022
Biomedical and Health Sciences
Mental health is a very prevalent issue in the world today. There are many studies on how physical and mental health affect each other. This study's goal was to discover the relationship bet…
ISEF · 2022
Biomedical and Health Sciences
Age-related macular degeneration (AMD) impacts the retina through an accumulation of unresolved oxidative stress. Diabetic Nephropathy and AMD have a strong association, with an odds ratio o…
ISEF · 2022
Translational Medical Science Second Award
Photosensitive epilepsy (PSE) is a neurological disorder, where seizures are triggered by aberrant flashes or specific spatial configurations of light. After COVID-19, billions of new intern…
ISEF · 2022
Translational Medical Science
Influenza virus causes an estimated 9.0-35.6 million severe illnesses and 850,000 deaths worldwide annually. Aided by its error-prone, open-ended RNA genome, the virus mutates rampantly to e…
ISEF · 2022
Biomedical and Health Sciences
CAR T-cell immunotherapy has proven to be effective in treating relapsed, refractory B-cell malignancies, such as non-Hodgkin’s lymphoma (NHL). Nevertheless, limitations have emerged from IL…
ISEF · 2022
Biomedical and Health Sciences
Purpose: Breast cancer has become one of the most common diseases among women worldwide. Using TS/A cells (established metastasizing adenocacinoma cell line from mouse), I studied the effect…
ISEF · 2022
Translational Medical Science Third Award
Aims: The purpose of this study was to use machine learning algorithms to build an effective, non-invasive and automated pipeline for grading and characterizing gliomas according to WHO 2016…
ISEF · 2022
Biomedical and Health Sciences
Parkinson’s Disease (PD) is the second most common neurodegenerative disease, and it plagues millions of people worldwide. PD is characterized by the loss of dopaminergic neurons, associated…
ISEF · 2022
Biomedical and Health Sciences Third Award
Mus musculus (mice) are often used to model the human immune system and to develop healthcare treatments because mouse immunology accurately recapitulates many aspects of the human immune sy…
ISEF · 2022
Biomedical and Health Sciences
West Nile virus (WNV) is the leading mosquito-borne disease in the United States but is not currently preventable through vaccination or treatable by any medications. It has caused over 2,50…
ISEF · 2022
Translational Medical Science Second Award
Alzheimer's disease (AD) is characterized by toxic aggregates formed by amyloid beta (AB) and tau, which kill memory and learning neurons. With only symptomatic treatments for mild-moderate…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Patients suffering from this condition exhibit a neuroinflammatory response mediated by microglial cells; this response h…
ISEF · 2022
Translational Medical Science
There is an unprecedented global mental health and substance abuse crisis including prescription drugs, affecting adults and youth. A recent FDA guidance requires abuse liability testing in…
ISEF · 2022
Translational Medical Science
The hearts of humans as well as Daphnia magna are striated and neurogenic. In humans, substances that induce sleep also lower blood pressure and heart rate. Research indicates that when D. m…
ISEF · 2022
Biomedical and Health Sciences Second Award
Cardiovascular diseases are the most common cause of death in the world. Because humans form few cardiomyocytes post-birth, engineering new myocardium could transform the treatment of heart…
ISEF · 2022
Translational Medical Science Second Award
This study evaluated the cytotoxicity of two Centella asiatica (CA) methanolic leaf extracts on the metastatic, triple negative breast cancer (TNBC) cell line MDA-MB-231. CA is a plant regio…
ISEF · 2022
Biomedical and Health Sciences
Extracellular vesicles (EVs) also known as Exosomes which are secreted by cells and play functional role in cell-cell communications. Recent advances in EV field have shown that they can be…
ISEF · 2022
Biomedical and Health Sciences
My research investigated the medicinal properties of Lomatium dissectum (called “doza” in our Native language) and Sambucus caerulea (elderberry, “hubui”) under laboratory conditions. Would…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Microplastics in the air cause respiratory diseases and worsen the health of the population, thus a nose filter with a biodegradable membrane may reduce their adverse effects on the respirat…
ISEF · 2022
Translational Medical Science
Paracetamol is a widely used drug due to its analgesic and antipyretic properties, however, intramolecular bonding that occurs between the drug’s chemical groups make it susceptible to a hea…
ISEF · 2022
Biomedical and Health Sciences
Multiple Sclerosis (MS) is a debilitating neurological disease affecting the central nervous system and significantly impacting patients’ quality of life. The disease involves inflammation,…
ISEF · 2022
Translational Medical Science
Neurodegenerative diseases are among the top five causes of death worldwide, with one major cause of these diseases being high levels of oxidative stress. Nano-antioxidants are emerging nano…
ISEF · 2022
Biomedical and Health Sciences
Aortic aneurysms have increased in the past two decades because of the aging population and the rise in the number of smokers. Aortic aneurysms affect about 2.9 million people and is the 13t…
ISEF · 2022
Biomedical and Health Sciences
One may be surprised to learn that the same ingredient, luteolin, is in a huge scope of supplements. Luteolin is the primary ingredient in therapeutic, neuroprotective, anti-inflammatory, an…
ISEF · 2022
Translational Medical Science
Dementia-related Cognitive Impairment (CI) is a neurodegenerative disorder, affecting over 55 million people worldwide and growing rapidly at the rate of one new case every three seconds. Th…
ISEF · 2022
Translational Medical Science Fourth Award
Colorectal cancer (CRC) is responsible for 864,989 deaths annually, making it the second leading cause of cancer death worldwide. The leading upstream cause of cancer deaths is a lack of cli…
ISEF · 2022
Translational Medical Science Second Award
The current practice of treating cancer with radiation, chemotherapy, and immunotherapy is a one-size-fits-all approach, in which patients with the same type and stage of cancer receive the…
ISEF · 2022
Translational Medical Science
Multiple myeloma (MM), an incurable cancer of the plasma cells in the bone marrow, is the 2nd most common hematological malignancy. Melphalan is an alkylator chemotherapy and an effective tr…
ISEF · 2022
Translational Medical Science Third Award
PANDwriting is a novel screening system for neurodegenerative diseases (NDs), particularly targeted to increase Alzheimer's Disease (AD) and Parkinson's Disease (PD) diagnostic access in low…
ISEF · 2022
Biomedical and Health Sciences Second Award
Exosomes secreted by pediatric bone marrow mesenchymal stem cells (pBMSC-Exos) demonstrate optimal characteristics for bone tissue engineering. MSC-Exos of alternate origin have expedited bo…