Browse real student projects, abstracts, and awards.
ISEF · 2022
Biomedical and Health Sciences First Award
There is currently no cure for chronic obstructive pulmonary disease (COPD), the third leading cause of death worldwide with over 70 million cases and 3.5 million deaths per year. Treatment…
ISEF · 2022
Translational Medical Science
Skin cancer is the most common cancer worldwide, with 2 people dying of skin cancer every hour in the United States alone (Skin Cancer Foundation, 2022). However, if detected early (before t…
ISEF · 2022
Translational Medical Science Fourth Award
Breast cancer is the most diagnosed cancer among women and the 5th leading cause of cancer-related mortality. Women in developing countries, especially sub-Saharan Africa, suffer from the hi…
ISEF · 2022
Biomedical and Health Sciences First Award
Stroke is the second leading cause of death worldwide, with 15 million people suffering from its debilitating effects each year. 87% of strokes are ischemic, where an artery narrows or becom…
ISEF · 2022
Translational Medical Science
Acute lymphoblastic leukemia (ALL) is one of the most common types of cancer in children. This study investigates a natural product that can be used as a possible agent for the treatment of…
ISEF · 2022
Translational Medical Science
More than 70 countries approve the consumption of artificial sweeteners (Ogungbemi et al., 2019). People, including pregnant women, regularly consume artificial sweeteners to substitute suga…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Alzheimers, a degenerative brain disorder, affected 6.1 million Americans in 2021. This debilitating disease is affecting more individuals each year. It disrupts an individual's cognitive ab…
ISEF · 2022
Biomedical and Health Sciences
Purpose: Acute myeloid leukemia (AML) is aggressive cancer with a poor prognosis. Most patients with AML ultimately relapse and succumb to cancer progression after receiving standard treatme…
ISEF · 2022
Translational Medical Science Fourth Award
Congestive heart failure (CHF) affects millions of patients and is associated with a high mortality rate. Early detection and treatment can improve outcomes and avoid hospitalization, but it…
ISEF · 2022
Translational Medical Science
Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus that has been declared a global pandemic since March 2020. Reverse transcription polymerase chain react…
ISEF · 2022
Translational Medical Science Fourth Award
1.5 million Americans suffer a traumatic brain injury every year. Without proper rest after even a mild concussion, repeated injuries to the brain build up and can lead to complications such…
ISEF · 2022
Translational Medical Science
Development of Novel, Selective, Orally Available Small Molecule CDK9 Inhibitors for Prostate Cancer Therapy - Mechanistic studies Abstract: Amplification of N-MYC causes its overexpression…
ISEF · 2022
Biomedical and Health Sciences
Alzheimer's disease (AD) is the most common neurodegenerative disease affecting more than 33 million people globally. Although several protein hallmarks associated with AD have been identifi…
ISEF · 2022
Translational Medical Science
Acute Myeloid Leukemia, or AML, is a malignant disorder of the bone marrow in which myeloid blasts engulf the bone marrow. To diagnose AML, physicians observe blast cell counts in the marrow…
ISEF · 2022
Biomedical and Health Sciences
As evidenced by the COVID-19 pandemic, infectious diseases have a dire impact on society. There is an urgent demand for developing strategies against infections. Dietary supplements, such as…
ISEF · 2022
Biomedical and Health Sciences
Limbic-predominant Age-related TDP-43 Encephalopathy (LATE) is an emerging dementia phenotype that mimics Alzheimer’s Disease (AD)-type amnestic dementia syndrome. However, LATE neuropatholo…
ISEF · 2022
Biomedical and Health Sciences
Increasing pharmaceutical options will help develop diverse individualized healthcare plans (GLIFWC Commission, 1993). Ethnopharmaceutical studies can provide pathways for diversification. Y…
ISEF · 2022
Biomedical and Health Sciences
As our country grows to the top obesity rates, the foods we deem healthy for us could potentially be harmful due to genetic modifications (GM) and chemicals used to create larger tastier foo…
ISEF · 2022
Biomedical and Health Sciences
Purpose: Retinopathy of prematurity (ROP), caused by abnormal retinal vessel growth, is a leading cause of worldwide blindness in children today. A treatment of ROP is to prevent pathologica…
ISEF · 2022
Translational Medical Science Third Award
Peripheral Arterial Disease (PAD) is caused by the blockage or narrowing of arteries supplying the lower extremities regions which affects approximately 10% of the U.S population and is one…
ISEF · 2022
Translational Medical Science
Cancer has a major impact on people around the world and is a large burden on society. Ultraviolet (UV) rays damage DNA, which significantly increases the risk of skin cancer, or melanoma. W…
ISEF · 2022
Biomedical and Health Sciences
Neurons, the cells composing the nervous system, are responsible for sending and receiving signals that result in everything from thoughts to movement. Macrophages, a type of cell in the imm…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Glioblastoma Multiforme (GBM) is one of the most lethal and aggressive brain cancers in humans. This project investigated the efficacy of a potential therapy for GBM-The Gliatrap. The Gliatr…
ISEF · 2022
Translational Medical Science
Fecal microbiota transplantation (FMT) is a new approach used for the treatment of inflammatory bowel disease (IBD) since this condition has been linked to an alteration of the gut microbiot…
ISEF · 2022
Biomedical and Health Sciences
In Vietnam, Ardisia gigantifolia is used as the best medicine to treat and prevent some gastric diseases. Ardisia gigantifolia contains saponin that can inhibit the growth of multiple cancer…
ISEF · 2022
Biomedical and Health Sciences Fourth Award
Glioblastoma is a malignant tumor of the central nervous system distinguished by its intra-tumoral heterogeneity and inevitable recurrence. A longitudinal axis of genomic evolution has been…
ISEF · 2022
Biomedical and Health Sciences
Alcohol addiction is a significant societal problem negatively impacting millions of people. Understanding the underlying mechanisms of addiction will aid efforts to provide care and a cure…
ISEF · 2022
Biomedical and Health Sciences
Though masks have now become an essential item the application of the now-widespread use of masks is greater than just in the context of protection from COVID-19. Throughout the day, mask-we…
ISEF · 2022
Translational Medical Science
An estimated 93 million adults in the United States are at high risk for serious vision loss, but only half visited an eye doctor in the past year. Prices for eye examinations are drasticall…
ISEF · 2022
Translational Medical Science
Early detection is the key to preventing arrhythmia-related complications. However, developing countries do not have the infrastructure, educated personnel, or devices to screen for arrhythm…