Browse real student projects, abstracts, and awards.
ISEF · 2023
Translational Medical Science
Glioblastoma (GBM), the most malignant brain tumor, remains nearly universally fatal despite aggressive cancer treatment involving surgery, radiation and temozolomide (TMZ) chemotherapy. TMZ…
ISEF · 2023
Biomedical and Health Sciences
The research and development of new medicine are expensive and time-consuming: the entire process from discovery to distribution takes up to 12 years, costing as much as $2.5 billion USD. Hu…
ISEF · 2023
Translational Medical Science
The development of therapeutic antibodies with high binding affinities is essential for various in vivo applications, including passive immunization, antigen-presence diagnostics, and cancer…
ISEF · 2023
Biomedical and Health Sciences
Autism spectrum disorder (ASD) is characterized by difficulties in processing sensorimotor information and general cortical excitability. Symptoms are likely attributable to impairments in c…
ISEF · 2023
Translational Medical Science
In multiple sclerosis (MS), existing diagnostic tools, including clinical magnetic resonance imaging (MRI) and neurological status scales, do not reliably represent disease severity or progr…
ISEF · 2023
Biomedical and Health Sciences
Recent research on the drug famotidine suggests it may be an affordable, accessible, safe, and effective treatment against COVID-19. Famotidine is a histamine 2 receptor (H2R) antagonist tha…
ISEF · 2023
Translational Medical Science
This study aimed to determine whether traumatic brain injury (TBI) causes learning and short-term memory (STM) deficits in Drosophila melanogaster, and if THIP, a GABA-A receptor agonist, wi…
ISEF · 2023
Translational Medical Science
Vinblastine is a cytotoxic drug that has been proven to stunt the growth of cancer cells by binding to the mitotic spindle during anaphase. Studies have shown that Alpha Tocopheryl, a type o…
ISEF · 2023
Biomedical and Health Sciences
Although stem cell transplants have made promising clinical progress as a treatment for leukemia and other blood cancers, their safety and the severe complications they pose have significant…
ISEF · 2023
Biomedical and Health Sciences
Myocardial infarction (MI), or heart attack, is the death of cardiac tissue to improper blood and oxygen flow. MI is a form of cardiovascular disease, the current leading cause of death, acc…
ISEF · 2023
Biomedical and Health Sciences Fourth Award
Type two Diabetes is an epidemic. Because there is no cure for diabetes and the current treatments can be expensive and inaccessible, exploration for more affordable management tools for the…
ISEF · 2023
Translational Medical Science Fourth Award
G-quadruplex structures (G4s) are one of many secondary structures that genomic DNA adopts, apart from its canonical B-form, and they are a vital part of cellular regulation. Sequences that…
ISEF · 2023
Translational Medical Science Third Award
Small cell lung cancer (SCLC) is an extremely aggressive form of lung cancer with a less than 5% five-year survival rate. The poor prognosis is mainly attributed to the lack of effective, lo…
ISEF · 2023
Translational Medical Science
Ginkgo biloba is an essential herbal agent that is effective on nerve cells and may have therapeutic or preventive effects with its water-soluble bioactive components. In our study, we worke…
ISEF · 2023
Translational Medical Science
I chose this project because the world around us is filled with information about products and substances. With the push of Vape sticks and alternatives like CBD, and the consequent sanction…
ISEF · 2023
Translational Medical Science
With just 5% survival rates, Liver cancer is one of the deadliest cancers in the world. Due to its low survival rates, early diagnosis of liver disease is extremely crucial. The aim of the p…
ISEF · 2023
Translational Medical Science
One of the most important metrics of cardiac health is ejection fraction. EF is the percentage of blood pumped out of the left ventricle each time the heart contracts and is most commonly an…
ISEF · 2023
Biomedical and Health Sciences
My research this year continued to investigate the anticancer effects of Lomatium dissectum, commonly known as fern leaf biscuit root (“doza" in our Native language), and Sambucus caerulea,…
ISEF · 2023
Biomedical and Health Sciences
The purpose of my research was to investigate the possible antibacterial properties of Artemisia tridentata (Big Sagebrush). I hypothesized that Artemisia tridentata would inhibit the growth…
ISEF · 2023
Translational Medical Science Third Award
This experiment was devoted to creating a mesenchymal stem cell therapy to repair the damage done by celiac disease, an autoimmune disease in which gluten produces an inflammatory response i…
ISEF · 2023
Biomedical and Health Sciences
Cancer is an extremely variant and personalized disease that is characterized by the disruption of regular cell functions. These disruptions can be analyzed by examining regulatory network c…
ISEF · 2023
Biomedical and Health Sciences
Alzheimer’s disease (AD) is the most common neurodegenerative disease and affects memory and learning. Recent data suggest mitochondrial fragmentation in AD likely underlies impaired mitocho…
ISEF · 2023
Translational Medical Science
Cancer accounts for nearly 10 million deaths annually, and treatment relies on identifying tissue origin. Traditional diagnostics are time-consuming, with wait times up to 120 days from symp…
ISEF · 2023
Biomedical and Health Sciences
Diabetes, characterized by hyperglycemia, affects human fertility. The animal model Caenorhabditis elegans is used to research human diseases due to its molecular-level similarities and ethi…
ISEF · 2023
Translational Medical Science First Award
Three million people in the U.S. suffer from gluten intolerance/celiac disease (CD). In these patients, the digestive system cannot digest gluten proteins. My project aims to solve this issu…
ISEF · 2023
Translational Medical Science
How has the intersection of nationalities and climate impacted the spread of Neglected Infectious Disease (NID) in Yunnan, China? By focusing on the prevalence of dengue viruses (DENV) and t…
ISEF · 2023
Translational Medical Science
Neuroendoscopy paired with external ventricular drainage consistently produces a higher positive patient prognosis in children with atypical teratoid rhabdoid tumor (T2N1M1) who developed an…
ISEF · 2023
Biomedical and Health Sciences Fourth Award
Alzheimer’s disease (AD) is the most common neurodegenerative disorder contributing to 60–80 % of cases of dementia worldwide, with no effective treatment so far. Alongside the amyloid-beta…
ISEF · 2023
Biomedical and Health Sciences
Neurodegenerative disorder is a wide range of conditions that results from progressive function loss or death of the nerve cells in the nervous system. Many studies confirmed that toluene, a…
ISEF · 2023
Translational Medical Science
Glioblastoma(GBM) is the most common malignancy of the central nervous system in adults. Despite medical advancements, the continued shortfall of many treatments such as Temozolomide, alongs…