38,465 real projects from ISEF, the Canada-Wide Science Fair, JSHS, AJAS, the Calgary Youth Science Fair and the California Science & Engineering Fair — searchable by meaning, and filterable by fair, year, category and award.
CSEF · 2026
Medicine & Physiology (Junior Division)
Millions of people have incorrect standing postures and gait and a majority of these people are unaware they even have this issue. Many people also have undiagnosed differences in leg length…
CSEF · 2026
Medicine & Physiology (Senior Division)
Sleep deprivation is a widespread public health issue that is known to impair many areas of cognitive function mainly due to its normalization in today's modern society. Yet, its effects und…
CSEF · 2026
Medicine & Physiology (Senior Division)
Epilepsy is a neurological disorder affecting approximately 50 million people worldwide and involves repeated seizures from abnormal neuron firing. Around 60% of patients have non-convulsive…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
With 1 in 10 Americans having a food allergy and half of them experiencing potentially fatal reactions, food allergies are a major problem. Allergies are the result of a person’s immune syst…
CSEF · 2026
Medicine & Physiology (Senior Division)
ASD is a neurodevelopmental condition that affects up to 3% of children. Though behavioral tests exist, there are no definitive genetic tests that measure the onset of ASD, leaving 25% of in…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Traditional cancer research has largely focused on well-characterized proteins, leaving approximately 40–50% of the human proteome—the "dark proteome"—poorly understood and potentially rich…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Parkinson’s disease progression is exacerbated by chronic neuroinflammation and excessive microglial activation, making inflammatory pathways promising therapeutic targets. Among these strat…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Visual information is detected and encoded in the retina through dozens of parallel pathways, with each pathway encoding a specific aspect of what we see. Each pathway is associated with a s…
CSEF · 2026
Medicine & Physiology (Senior Division)
Knee injuries and osteoarthritis affect an estimated 50 million individuals worldwide every year. Many patients undergo unnecessary and invasive procedures even after diagnostic imaging, wit…
CSEF · 2026
Medicine & Physiology (Junior Division)
Type 2 Diabetes (T2D) is rapidly increasing among youth (2M), and projected to surge by 700% in 2060. Current medical strategies are reactive, focusing on post diagnosis treatment. Motivated…
CSEF · 2026
Medicine & Physiology (Senior Division)
Seizures impact 10% of the global population, with epilepsy developing in 1-2%. Seizure duration is an important marker of severity, with longer duration leading to increased morbidity and m…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Triple negative breast cancer (TNBC) is a highly-aggressive cancer that is difficult to treat because it lacks estrogen receptors, progesterone receptors, and HER2 protein that drive the maj…
CSEF · 2026
Medicine & Physiology (Senior Division)
Liver shunts can be a life-threatening disease in dogs and cats; these are abnormal blood vessels that bring blood returning from the intestines into systemic circulation, bypassing the live…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Rehabilitation following knee injury is commonly guided by intermittent clinical observation and subjective self-assessment, leaving a critical gap in objective, continuous feedback during e…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) affects 33.7% of American adults, yet early detection remains challenging because diagnostic methods like FibroScan® are expe…
CSEF · 2026
Medicine & Physiology (Senior Division)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by mitochondrial dysfunction, impaired protein clearance, and accumulation of pathological aggregates. Anal…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Background/Objectives: Individuals with arrhythmia who survived COVID-19 could be susceptible to long-term cardiovascular complications and clinical outcomes. Methods: We performed a retrosp…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Annually, 20 million people are diagnosed with cancer, contributing to over 9.7 million deaths. Nearly 25% of these cases are linked to mutations in the KRAS gene, which normally functions a…
CSEF · 2026
Medicine & Physiology (Senior Division)
The nucleus tractus solitarius (NTS) and the spinal cord are important sensory hubs that project interoceptive and somatosensory information to similar brain regions, respectively; however,…
CSEF · 2026
Medicine & Physiology (Junior Division)
Pregnancy complications drive approximately 13.4 million preterm births globally each year and contribute to roughly 900,000 preventable neonatal deaths from conditions such as preeclampsia,…
CSEF · 2026
Medicine & Physiology (Senior Division)
This project investigated how dietary macronutrients affect the rate of glucose diffusion across a semi-permeable membrane. The hypothesis was that fiber and protein would reduce glucose dif…
CSEF · 2026
Medicine & Physiology (Senior Division)
The glial scar that forms after ischemic injury creates a structurally and functionally complex barrier, yet how it regulates neural stem cell (NSC) fate remains unclear. Single-cell RNA seq…
CSEF · 2026
Medicine & Physiology (Junior Division)
Antibiotic-resistant Pseudomonas aeruginosa is responsible for an estimated 559,000 deaths annually worldwide, and for immunocompromised patients like myself, it is a leading cause of mortal…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Alzheimer’s disease (AD) affects 1 in 9 Americans over age 65, yet 98% of clinical trials fail, reflecting a mismatch between cellular heterogeneity and coarse-grained patient-level single-t…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Stroke and migraine with aura, which affect over 300 million people globally, present with similar visual symptoms requiring differentiation through costly neuroimaging that may not be avail…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Multiple Sclerosis (MS) is a chronic autoimmune neurological disorder affecting 2.9 million people worldwide. For MS, an incurable disease, the prevention of progression (from RRMS to PPMS)…
CSEF · 2026
Medicine & Physiology (Senior Division)
The California wildfires of 2025 (Palisades and Eaton) were the second-worst recorded weather disasters, with potential severe health consequences. It is becoming clear that cardiac abnormal…
CSEF · 2026
Medicine & Physiology (Senior Division)
In the field of microvascular diagnostics, the most significant diseases are those that silently compromise systemic health by attacking the smallest vessels in the human body. Nailfold capi…
CSEF · 2026
Medicine & Physiology (Senior Division)
Breast cancer recurrence rates reach up to 50%, yet existing clinical tools rely on single modality data or repeated medical check-ups. The proposed model, OncoTwin, is a novel recurrence-ri…
CSEF · 2026
Medicine & Physiology (Track 2) (Senior Division)
Alzheimer’s disease (AD) affects nearly 55 million people worldwide and is characterized by progressive cognitive decline associated with tau neurofibrillary tangles and β-amyloid plaques. A…