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ISEF · 2026
Cellular and Molecular Biology
Multiple myeloma (MM) is a hematologic malignancy characterized by the uncontrolled proliferation of malignant plasma cells in the bone marrow. This study explored the potential of Pristimer…
ISEF · 2026
Cellular and Molecular Biology
Azole antifungals have served as frontline therapies for Candida infections. However, increasing azole-resistant Candida species presents a real clinical challenge requiring alternative anti…
ISEF · 2026
Cellular and Molecular Biology
Epilepsy affects over 50 million people, and one in three cannot stop their seizures with medication. Neuromodulatory therapies are the leading alternative, but development has been bottlene…
ISEF · 2026
Cellular and Molecular Biology
Modern nucleic acid sequencing enables rapid and cost-effective genomic analysis, but for low-input samples, amplification via polymerase chain reaction (PCR) remains a critical bottleneck.…
ISEF · 2026
Cellular and Molecular Biology
Colorectal cancer (CRC) is a leading cause of cancer-related mortality in the United States, with metastasis responsible for the majority of CRC deaths. Emerging research suggests that micro…
ISEF · 2026
Cellular and Molecular Biology
Ovarian cancer is the deadliest gynecological cancer, with a five year survival rate that still barely exceeds 50%. Mesenchymal stem cells (MSCs) are a stromal cell population in the tumor m…
ISEF · 2026
Cellular and Molecular Biology
Translation initiation is a major control point in bacterial gene expression, yet how initiation factors affect population level growth remains poorly quantified, specifically under environm…
ISEF · 2026
Cellular and Molecular Biology
Insulin-like growth factor 2 (IGF-2) is a regulatory peptide involved in neuroplasticity, memory consolidation, and neuroprotection in the CNS. Despite the well-documented association betwee…
ISEF · 2026
Cellular and Molecular Biology
Isoflurane is an FDA-approved volatile anesthetic used to induce and maintain general anesthesia. Isoflurane hyperpolarizes membrane potential by selectively enhancing K+ channels and inhibi…
ISEF · 2026
Cellular and Molecular Biology
Drug combination therapy is a cornerstone of modern oncology, but identifying effective combinations for a patient's specific tumor remains difficult as possible combinations grow rapidly wi…
ISEF · 2026
Cellular and Molecular Biology
Glioblastoma is a highly aggressive and treatment-resistant brain tumor with a five-year survival rate of 6.9%, necessitating exploration of novel therapeutic strategies. Transient receptor…
ISEF · 2026
Cellular and Molecular Biology
Cardiovascular disease remains the leading global cause of mortality, with myocardial infarction resulting in permanent myocardial loss due to the limited regenerative capacity of adult card…
ISEF · 2026
Cellular and Molecular Biology
MicroRNAs (miRNAs), small noncoding RNA genes, play crucial roles in regulating gene expression in human development and cancer. The let-7 miRNA is involved in various cellular processes, in…